Asthma: defining of the persistent adult phenotypes

835Citations
Citations of this article
519Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The common disease asthma is probably not a single disease, but rather a complex of multiple, separate syndromes that overlap. Although clinicians have recognised these different phenotypes for many years, they have remained poorly characterised, with little known about the underlying pathobiology contributing to them. Development of targeted therapies for asthma, and phenotype-specific clinical trials have raised interest in these phenotypes. Improved understanding of these phenotypes in complex diseases such as asthma will also improve our ability to link specific genotypes to their associated disease, which should help development of biomarkers. However, there is no standardised method to define asthma phenotypes. This Review analyses some of the methods that have been used to define asthma phenotypes and proposes an integrated method of classification to improve our understanding of these phenotypes. © 2006 Elsevier Ltd. All rights reserved.

Cite

CITATION STYLE

APA

Wenzel, S. E. (2006, August 26). Asthma: defining of the persistent adult phenotypes. Lancet. Elsevier B.V. https://doi.org/10.1016/S0140-6736(06)69290-8

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free