Sign up & Download
Sign in

Cell-derived microparticles in haemostasis and vascular medicine

by Laurent Burnier, Pierre Fontana, Brenda R. Kwak, Angelillo Scherrer Anne
Thrombosis and Haemostasis ()

Abstract

Considerable interest for cell-derived microparticles has emerged, pointing out their essential role in haemostatic response and their potential as disease markers, but also their implication in a wide range of physiological and pathological processes. They derive from different cell types including platelets - the main source of microparticles - but also from red blood cells, leukocytes and endothelial cells, and they circulate in blood. Despite difficulties encountered in analyzing them and disparities of results obtained with a wide range of methods, microparticle generation processes are now better understood. However, a generally admitted definition of microparticles is currently lacking. For all these reasons we decided to review the literature regarding microparticles in their widest definition, including ectosomes and exosomes, and to focus mainly on their role in haemostasis and vascular medicine.

Cite this document (BETA)

Readership Statistics

72 Readers on Mendeley
by Discipline
 
 
 
by Academic Status
 
26% Ph.D. Student
 
14% Student (Master)
 
13% Student (Bachelor)
by Country
 
3% Netherlands
 
3% Ireland
 
3% United Kingdom

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in