Abstract
Different thymidine derivatives bearing either an iodoaryl moiety at the 5′ position or a dialkylsilyl group at the 3′ position have been efficiently synthesized as precursors for carbon-11 or fluorine-18 labeling, respectively. Furthermore, iodoarylated thymidine derivatives have been incorporated into oligonucleotides giving an original way to label them with carbon-11. © 2009 Elsevier Ltd. All rights reserved.
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CITATION STYLE
James, D., Escudier, J. M., Amigues, E., Schulz, J., Vitry, C., Bordenave, T., … Fouquet, E. (2010). A “click chemistry” approach to the efficient synthesis of modified nucleosides and oligonucleotides for PET imaging. Tetrahedron Letters, 51(8), 1230–1232. https://doi.org/10.1016/j.tetlet.2009.12.120
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