Development of monocytes, macrophages, and dendritic cells

2.3kCitations
Citations of this article
3.5kReaders
Mendeley users who have this article in their library.
Get full text

Abstract

Monocytes and macrophages are critical effectors and regulators of inflammation and the innate immune response, the immediate arm of the immune system. Dendritic cells initiate and regulate the highly pathogen-specific adaptive immune responses and are central to the development of immunologic memory and tolerance. Recent in vivo experimental approaches in the mouse have unveiled new aspects of the developmental and lineage relationships among these cell populations. Despite this, the origin and differentiation cues for many tissue macrophages, monocytes, and dendritic cell subsets in mice, and the corresponding cell populations in humans, remain to be elucidated.

Cite

CITATION STYLE

APA

Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010, February 5). Development of monocytes, macrophages, and dendritic cells. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1178331

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free