Control over when and where nanostructures arise is essential for the self-assembly of dynamic or multicomponent devices. We design and construct a DNA origami seed for the control of DAE-E tile DNA nanotube assembly. Seeds greatly accelerate nanotube nucleation and growth because they serve as nanotube nucleation templates. Seeds also control nanotube circumference. Simulations predict nanotube growth rates and suggest a small nucleation barrier remains when nanotubes grow from seeds. © 2013 American Chemical Society.
CITATION STYLE
Mohammed, A. M., & Schulman, R. (2013). Directing self-assembly of DNA nanotubes using programmable seeds. Nano Letters, 13(9), 4006–4013. https://doi.org/10.1021/nl400881w
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