The enantioselective cyclization of N-acyliminium ions generated in situ from tryptamine is promoted with high enantioselectivity by a new chiral thiourea catalyst. This represents the first successful system for asymmetric catalysis of the Pictet-Spengler reaction. Copyright © 2004 American Chemical Society.
CITATION STYLE
Taylor, M. S., & Jacobsen, E. N. (2004). Highly enantioselective catalytic acyl-Pictet-Spengler reactions. Journal of the American Chemical Society, 126(34), 10558–10559. https://doi.org/10.1021/ja046259p
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