Sign up & Download
Sign in

Introduction to the hepatic encephalopathy scoring algorithm (HESA)

by Tarek I. Hassanein, Robin C. Hilsabeck, William Perry
Digestive Diseases and Sciences ()

Abstract

A primary obstacle to early diagnosis and treatment of hepatic encephalopathy (HE) is the lack of a well-validated, standardized assessment method. The purpose of this study was to present preliminary validity data on a new method of grading HE, the Hepatic Encephalopathy Scoring Algorithm (HESA), which combines clinical impressions with neuropsychological performances to characterize HE. Participants were 49 inpatients admitted for complications of end stage liver disease. Each participant's level of HE was graded using HESA and the West Haven Criteria (WHC) by independent raters blinded to each other's rating. A moderately strong association was found between the two grading methods (r = 0.60), and individual HESA clinical and neuropsychological indicators were good discriminators among grades. The results also suggest HESA may be more sensitive to mental status impairment in the middle grades of HE than WHC. These findings suggest HESA holds promise as a multi-method approach to grading all levels of HE.

Cite this document (BETA)

Readership Statistics

8 Readers on Mendeley
by Discipline
 
 
 
by Academic Status
 
25% Assistant Professor
 
13% Senior Lecturer
 
13% Student (Bachelor)
by Country
 
13% Germany
 
13% Spain
 
13% United States

Tags

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in