Abstract
Background: Rare mutations of the low-density lipoprotein receptor gene (LDLR) cause familial hypercholesterolemia, which increases the risk for coronary artery disease (CAD). Less is known about the implications of common genetic variation in the LDLR gene regarding the variability of cholesterol levels and risk of CAD.
Cite
CITATION STYLE
Linsel-Nitschke, P., Gö Tz, A., Erdmann, J., Braenne, I., Braund, P., Hengstenberg, C., … Schunkert, H. (n.d.). Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study for the Wellcome Trust Case Control Consortium (WTCCC) and the Cardiogenics Consortium.
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