Sign up & Download
Sign in

Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products

by Jana Pardeike, Aiman Hommoss, Rainer H. Müller
International Journal of Pharmaceutics ()

Abstract

Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC) by the composition of the solid particle matrix. Both are an alternative carrier system to liposomes and emulsions. This review paper focuses on lipid nanoparticles for dermal application. Production of lipid nanoparticles and final products containing lipid nanoparticles is feasible by well-established production methods. SLN and NLC exhibit many features for dermal application of cosmetics and pharmaceutics, i.e. controlled release of actives, drug targeting, occlusion and associated with it penetration enhancement and increase of skin hydration. Due to the production of lipid nanoparticles from physiological and/or biodegradable lipids, this carrier system exhibits an excellent tolerability. The lipid nanoparticles are a "nanosafe" carrier. Furthermore, an overview of the cosmetic products currently on the market is given and the improvement of the benefit/risk ratio of the topical therapy is shown. © 2008 Elsevier B.V. All rights reserved.

Cite this document (BETA)

Page 1
hidden
Page 2
hidden

Readership Statistics

179 Readers on Mendeley
by Discipline
 
 
 
by Academic Status
 
30% Ph.D. Student
 
25% Student (Master)
 
7% Doctoral Student
by Country
 
3% Brazil
 
2% Portugal
 
2% India

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in