Living related liver transplantation in children

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Abstract

Background: Living related liver transplantation (LRLT) has become established for treating children with end-stage liver disease. The aim of this study was to review a single-centre experience of left lateral segment liver transplants from living donors in children. Methods: Fifty left lateral segment LRLT procedures have been performed since 1993. There were 17 girls and 33 boys, of median age 1.5 years (range 0.5 to 13 years), with a median weight of 10 (range 0.7-44) kg. Donors included 23 mothers, 26 fathers and one uncle, with a median age of 33 (range 19-46) years. Results: At a median follow-up of 86 months, there was no donor mortality and low morbidity. Patient and graft survival rates were 98, 96 and 96 per cent, and 98, 96 and 93 per cent at 1, 3 and 5 years respectively. Three children had a second transplant at a median of 9 years after the first. The incidence of hepatic artery thrombosis, portal vein thrombosis and biliary complications was 6, 4 and 14 per cent respectively. Conclusion: Living related liver transplantation has good long-term results in children. Copyright © 2008 British Journal of Surgery Society Ltd.

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APA

Heaton, N., Faraj, W., Vilca Melendez, H., Jassem, W., Muiesan, P., Mieli-Vergani, G., … Rela, M. (2008). Living related liver transplantation in children. British Journal of Surgery, 95(7), 919–924. https://doi.org/10.1002/bjs.6060

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