Background: Multicentre clinical trials are challenged by high administrative burden, data management pitfalls and costs. This leads to a reduced enthusiasm and commitment of the physicians involved and thus to a reluctance in conducting multicentre clinical trials. Objective: The purpose of this study was to develop a web-based open source platform to support a multi-centre clinical trial. Methods: We developed on Drupal, an open source software distributed under the terms of the General Public License, a web-based, multi-centre clinical trial management system with the design science research approach. Results: This system was evaluated by user-testing and well supported several completed and on-going clinical trials and is available for free download. Conclusion: Open source clinical trial management systems are capable in supporting multi-centre clinical trials by enhancing efficiency, quality of data management and collaboration. © 2014 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.
CITATION STYLE
Raptis, D. A., Mettler, T., Fischer, M. A., Patak, M., Lesurtel, M., Eshmuminov, D., … Breitenstein, S. (2014). Managing multicentre clinical trials with open source. Informatics for Health and Social Care, 39(2), 67–80. https://doi.org/10.3109/17538157.2013.812647
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