Gastroparesis is a condition of abnormal gastric motility characterized by delayed gastric emptying without evidence of mechanical outlet obstruction. The authors describe complete remission of recurrent postprandial discomfort, nausea, and vomiting within 1 week of starting mirtazapine in a gastroparetic patient who had failed to respond, in 7 months, to conventional prokinetics (erythromycin, metoclopramide, domperidone, perphenazine, itopride, bethanechol, and/or tegaserod) and pyloric injection of botulinum toxin. This is the first report to show that mirtazapine may be an effective alternative when gastroparesis is refractory to conventional measures. Copyright © 2006 The Academy of Psychosomatic Medicine.
CITATION STYLE
Kim, S. W., Shin, I. S., Kim, J. M., Kang, H. C., Mun, J. U., Yang, S. J., & Yoon, J. S. (2006). Mirtazapine for severe gastroparesis unresponsive to conventional prokinetic treatment. Psychosomatics. American Psychiatric Publishing Inc. https://doi.org/10.1176/appi.psy.47.5.440
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