Papers that report drug trials

  • Greenhalgh T
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Abstract

Summary points Pharmaceutical “reps” are now much more informative than they used to be, but they may show ignorance of basic epidemiology and clinical trial design The value of a drug should be expressed in terms of safety, tolerability, efficacy, and price The efficacy of a drug should ideally be measured in terms of clinical end points that are relevant to patients; if surrogate end points are used they should be valid Promotional literature of low scientific validity (such as uncontrolled before and after trials) should not be allowed to influence practice

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APA

Greenhalgh, T. (1997). Papers that report drug trials. British Journal of Medicine, 315(August), 480–483.

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