A one-pot synthesis of tetrahydroisoquinoline alkaloids in a phosphate buffer has been achieved, and a reaction mechanism proposed. The utilisation of mild reaction conditions readily afforded a range of isoquinolines, including norcoclaurine. © 2011 Royal Society of Chemistry.
CITATION STYLE
Pesnot, T., Gershater, M. C., Ward, J. M., & Hailes, H. C. (2011). Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids. Chemical Communications, 47(11), 3242–3244. https://doi.org/10.1039/c0cc05282e
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