Sign up & Download
Sign in

Repopulation of cancer cells during therapy: an important cause of treatment failure.

by John J Kim, Ian F Tannock
Nature reviews. Cancer ()

Abstract

Radiotherapy and chemotherapy are given in multiple doses, which are spaced out to allow the recovery of normal tissues between treatments. However, surviving cancer cells also proliferate during the intervals between treatments and this process of repopulation is an important cause of treatment failure. Strategies developed to overcome repopulation have improved clinical outcomes, and now new strategies to inhibit repopulation are emerging in parallel with advances in the understanding of underlying biological mechanisms.

Cite this document (BETA)

Readership Statistics

80 Readers on Mendeley
by Discipline
 
 
 
by Academic Status
 
19% Researcher (at a non-Academic Institution)
 
19% Ph.D. Student
 
18% Post Doc
by Country
 
5% United States
 
3% United Kingdom
 
3% Netherlands

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in