Selective publication of antidepressant trials and its influence on apparent efficacy.

doi:10.1056/NEJMsa065779

Selective publication of antidepressant trials and its influence on apparent efficacy.

by Erick H Turner, Annette M Matthews, Eftihia Linardatos, Robert A Tell, Robert Rosenthal

View in Mendeley Desktop In your library Save reference to library

The New England Journal of Medicine (2008)

Volume: 358, Issue: 3, Publisher: Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA. turnere@ohsu.edu, Pages: 252-60

ISSN: 15334406
ISBN: ISSN~~3583252p
DOI: 10.1056/NEJMsa065779
PubMed: 18199864

Available from The New England Journal of Medicine

or

Abstract

Evidence-based medicine is valuable to the extent that the evidence base is complete and unbiased. Selective publication of clinical trials-and the outcomes within those trials-can lead to unrealistic estimates of drug effectiveness and alter the apparent risk-benefit ratio.

Author-supplied keywords

antidepressive agents antidepressive agents therapeutic use clinical trials topic evidence based medicine government regulation humans nonparametric outcome assessment (health care)outcome assessment (health care) methods publication bias publication bias statistics & numerical data publishing publishing statistics & numerical data review literature topic statistics treatment outcome united states united states food drug administration

Cite this document ^(BETA)

Readership Statistics

173 Readers on Mendeley

by Discipline

49% Medicine

27% Psychology

11% Biological Sciences

by Academic Status

18% Ph.D. Student

10% Other Professional

10% Student (Master)

by Country

29% United States

12% Canada

9% United Kingdom

Selective publication of antidepressant trials and its influence on apparent efficacy.

Abstract

Author-supplied keywords

Related

Cite this document (BETA)

Related Full-Text Papers for Free

Readership Statistics

Tags

Sign up today - FREE

Start using Mendeley in seconds!

Cite this document ^(BETA)