Emotionally significant experiences tend to be well remembered, and the amygdala has a pivotal role in this process. But the efficient encoding of emotional memories can become maladaptive severe stress often turns them into a source of chronic anxiety. Here, we review studies that have identified neural correlates of stress-induced modulation of amygdala structure and function from cellular mechanisms to their behavioural consequences. The unique features of stress-induced plasticity in the amygdala, in association with changes in other brain regions, could have long-term consequences for cognitive performance and pathological anxiety exhibited in people with affective disorders. © 2009 Macmillan Publishers Limited. All rights reserved.
CITATION STYLE
Roozendaal, B., McEwen, B. S., & Chattarji, S. (2009, June). Stress, memory and the amygdala. Nature Reviews Neuroscience. https://doi.org/10.1038/nrn2651
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