Approach to the immunocompromised patient with pulmonary nodules

Abstract

In immunocompromised hosts, the lung is a frequent site of opportunistic infection and pulmonary nodules are a common finding. Clinicians caring for these patients have an expanded selection of options available for empiric treatment and new diagnostic tools. Increased use of prophylaxis with broad-spectrum antifungals (eg, posaconazole and voriconazole) has complicated the approach to empiric therapy. This review discusses new developments in epidemiology, diagnosis, and therapy that inform the approach to the immunocompromised patient with pulmonary nodules. Copyright © 2009 by Current Medicine Group LLC.