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Papers in this group

1 - 20 of 2,575
  1. MOTIVATION: The interaction between drugs and their targets, often proteins, and between antibodies and their targets is important for planning and analyzing investigational and therapeutic interventions in many biological systems. Although…
  2. MOTIVATION: Somatic homozygous deletions of chromosomal regions in cancer, while not necessarily oncogenic, may lead to therapeutic vulnerabilities specific to cancer cells compared with normal cells. A recently reported example is the loss of one…
  3. Virtually since the discovery of nitrogen-fixing Rhizobium-legume symbioses, researchers have dreamed of transferring this capability into nonlegume crop species (for example, corn). In general, nonlegumes were assumed to lack the ability to respond…
  4. Glucose confers acid resistance on exponentially growing bacteria by repressing formation of the cyclic AMP (cAMP)-cAMP receptor protein (CRP) complex and consequently activating acid resistance genes. Therefore, in a glucose-rich growth…
  5. Dissolved inorganic nitrogen (DIN) uptake by marine heterotrophic bacteria has important implications for the global nitrogen (N) and carbon (C) cycles. Bacterial nitrate utilization is more prevalent in the marine environment than traditionally…