AntibodyEngineering

AntibodyEngineering

In this group: 29 papers · 4 members

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Mahboob Imtiyaz

Mahboob Imtiyaz is now following this group

1st February

Riki Stevenson added a document to this group

Stability engineering of scFvs for the development of bispecific and multivalent antibodies.

12th August, 2010

Riki Stevenson added documents to this group

VH/VL interface engineering to promote selective expression and inhibit conformational isomerization of thrombopoietin receptor agonist single-chain diabody.

Structure-based engineering of a monoclonal antibody for improved solubility.

AUTO-MUTE: web-based tools for predicting stability changes in proteins due to single amino acid replacements.

Improvement of tumor targeting and antitumor activity by a disulphide bond stabilized diabody expressed in Escherichia coli.

Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion.

7th July, 2010

Riki Stevenson added a document to this group

Transcytosis and catabolism of antibody.

22nd June, 2010

Riki Stevenson added a document to this group

Reduced elimination of IgG antibodies by engineering the variable region.

4th June, 2010

Riki Stevenson added documents to this group

The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies.

Molecular recognition by a binary code.

The importance of being tyrosine: Lessons in molecular recognition from minimalist synthetic binding proteins

Use of amino acid composition to predict epitope residues of individual antibodies.

13th May, 2010

Riki Stevenson added a document to this group

Molecular immunology of experimental primary tularemia in mice infected by respiratory or intradermal routes with type A Francisella tularensis.

8th May, 2010

Riki Stevenson added a document to this group

Single chain Fab (scFab) fragment.

7th May, 2010

Riki Stevenson added documents to this group

Effect of domain order on the activity of bacterially produced bispecific single-chain Fv antibodies.

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR.

18th April, 2010

Riki Stevenson added documents to this group

Improving solubility and refolding efficiency of human V(H)s by a novel mutational approach.

Engineering antibodies for stability and efficient folding.

Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework.

Knobs-into-holes’ engineering of antibody C H 3 domains for heavy chain heterodimerization

Functional aspects of co-variant surface charges in an antibody fragment

10th March, 2010

Created by Riki Stevenson

10th March, 2010

Owned by Riki Stevenson

Researcher (at a non-Academic Institution)

Biological Sciences

4 members

Gregor Gatomski

Mahboob Imtiyaz

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