Toxicology

Papers in this group tagged with "experimental design"

1. Incorporating biomarkers into clinical trial designs: points to consider.

   Edward Bradley in Nature biotechnology (2012)

   Commentary in a Focus on Cancer Technologies. In an environment where the regulatory and reimbursement authorities continue to raise the bar for new oncology therapies, how are sponsors adapting clinical trial designs?

   Added 2012-07-20 28 readers
2. Environmental standardization: cure or cause of poor reproducibility in animal experiments?

   S Helene Richter, Joseph P Garner, Hanno Würbel in Nature methods (2009)

   It is widely believed that environmental standardization is the best way to guarantee reproducible results in animal experiments. However, mounting evidence indicates that even subtle differences in laboratory or test conditions can lead to…

   Added 2010-12-01 59 readers
3. Systematic variation improves reproducibility of animal experiments.

   S Helene Richter, Joseph P Garner, Corinna Auer, Joachim Kunert, Hanno Würbel in Nature methods (2010)

   Added 2010-08-02 39 readers
4. Environmental standardization: cure or cause of poor reproducibility in animal experiments?

   S Helene Richter, Joseph P Garner, Hanno Würbel in Nature methods (2009)

   It is widely believed that environmental standardization is the best way to guarantee reproducible results in animal experiments. However, mounting evidence indicates that even subtle differences in laboratory or test conditions can lead to…

   Added 2010-08-02 59 readers