Papers in this group
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Background: The gene expression is usually described in the literature as a transcription factor X that regulates the target gene Y. Previously, some studies discovered gene regulations by using information from the biomedical literature and most of…
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Advances in microarray technology have resulted in an exponential rise in gene expression data. Partially as a result of this, full genome sequences have been reported for many organisms. In addition several methods have been developed (a) for…
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In Arabidopsis thaliana, four major regulators (ABSCISIC ACID INSENSITIVE3 ABI3, FUSCA3 FUS3, LEAFY COTYLEDON1 LEC1, and LEC2) control most aspects of seed maturation, such as accumulation of storage compounds, cotyledon identity, acquisition of…
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A famous joke story that exhibits the traditionally awkward alliance between theory and experiment and showing the differences between experimental biologists and theoretical modelers is when a University sends a biologist, a mathematician, a…
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MOTIVATION: To meet the demands of large-scale sequencing, thousands of clones must be fingerprinted and assembled into contigs. To determine the order of clones, a typical experiment is to digest the clones with one or more restriction enzymes and…
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ABSTRACT: Modern life sciences research increasingly relies on computational solutions, from large scale data analyses to theoretical modeling. Within the theoretical models Boolean networks occupy an increasing role as they are eminently suited at…
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The interactions between proteins, DNA, and RNA in living cells constitute molecular networks that govern various cellular functions. To investigate the global dynamical properties and stabilities of such networks, we studied the cell-cycle…