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Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman Here's a very clever paper that combines bibliolmetrics with second-gen sequencing to define the brain's ignorome--the set of genes which are highly and selectively expressed in the CNS yet poorly studied in the neuroscience literaturwe.   Out of 650 genes with CNS-specific expression, about 38 have one or fewer neuroscience papers.   In contrast t...
7th March
Robert Calin-Jageman
Robert Calin-Jageman Also, three cool new technique papers well worth reading. CRISPR-Cas uses a restriction enzyme targeted by a 20 nucleotide motif to allow genomic editing in basically any cell type in any organism. Revolutionary. Also, a cool strategy for selective targeting of proteins for lysosomal degredation--seems arduous to design for your target, but I im...
7th March
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Anna Babii likes this.
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman I added a trio of articles on animal models of psychiatric disorders. The article "Crazy like a fox" is a bit over the top in places, but it makes some interesting points about the logical mindfield of modelling specifically psychological disorders in animals. As a counterpoint, I've also included Koob's recent review of animal models (an update,...
27th February
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman Well, it finally looks like the funders are weighing in on the sorry state of scientific rigor in neuroscience. Good to see, but a bit of a yawn in its call for reforms, which seems to mainly just be a more training in statistics. I don't think the problem is poor statistical training--it's that most researchers know enough about statistics to ma...
27th February
Robert Calin-Jageman
Added an interesting summary of a failed clinical trial for DBS.
Natalya Krupenina likes this.
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman added a document to this group
Renee Presley likes this.
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
Robert Calin-Jageman
Robert Calin-Jageman added documents to this group
636,120 Ways to Have Posttraumatic Stress Disorder
Many Labs 1 Investigating variation in replicability : A “ Many Labs ” Replication Project Authors ’ note : We thank Eugene Caruso , Melissa Ferguson , Daniel Oppenheimer , and Norbert Schwarz for their feedback on the design of the materials . This project was supported by grants to the second and fifty-first authors from Project Implicit . Ratliff and Nosek are consultants of Project Implicit , Inc ., a non-profit organization that includes in its mission “ to develop and deliver methods for investigating and applying phenomena of implicit social cognition , including especially phenomena of implicit bias based on age , race , gender or other factors .” Correspondence concerning this paper should be addressed to Richard A . Klein , University of Florida , raklein@ufl.edu . Materials , data , and original proposal are available at the project page : Many Labs 2 Abstract Although replication is a central tenet of science , direct replications are rare in psychology . This research tested variation in the replicability of thirteen classic and contemporary effects across 36 independent samples totaling 6 , 344 participants . In the aggregate , ten effects replicated consistently . One effect – imagined contact reducing prejudice – showed weak support for replicability . And two effects – flag priming influencing conservatism and currency priming influencing system justification – did not replicate . We compared whether the conditions such as lab versus online or U . S . versus international sample predicted effect magnitudes . By and large they did not . The results of this small sample of effects suggest that replicability is more dependent on the effect itself than on the sample and setting used to investigate the effect . Word Count = 121 words
Spurious group differences due to head motion in a diffusion MRI study
Changes in Brain Function Occur Years before the Onset of Cognitive Impairment
Memorable Trends

About this group

This is my selection of recent papers in neuroscience that reflect big/important findings. I try to add articles monthly, and focus on articles that change the way I think about things or that provide good summaries of areas that I'm interested in. I hope you'll find it useful to follow this group and/or subscribe to the rss feed. If you come across an article I should include, send me a message via Mendeley.

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