Biomarker Commons

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Papers in this group

1. A novel multiplex method for the simultaneous detection and relative quantification of pollen allergens

   Sonia Morales, Antonio J Castro, Jose C Jimenez-Lopez, Jose F Florido, Maria I Rodriguez-Garcia, Juan D Alche in ELECTROPHORESIS (2012)

   Added 2012-03-22 1 reader
2. Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay.

   Andrei P Drabovich, Keith Jarvi, Eleftherios P Diamandis in Molecular & cellular proteomics : MCP (2011)

   Seminal plasma is a promising biological fluid to use for non-invasive clinical diagnostics of male reproductive system disorders. To verify a list of prospective male infertility biomarkers, we developed a multiplex selected reaction monitoring…

   Added 2012-03-20 6 readers
3. Verification of a biomarker discovery approach for detection of Down syndrome in amniotic fluid via multiplex selected reaction monitoring (SRM) assay.

   Chan-Kyung J Cho, Andrei P Drabovich, Ihor Batruch, Eleftherios P Diamandis in Journal of proteomics (2011)

   Prenatal screening test for Down syndrome (DS) can be improved by discovery of novel biomarkers. A multiplex selected reaction monitoring (SRM) assay was developed to test previously identified thirteen candidate proteins in amniotic fluid (AF). One…

   Added 2012-03-20 6 readers
4. Biomarkers and surrogate end points — the challenge of statistical validation

   Marc Buyse, Daniel J Sargent, Axel Grothey, Alastair Matheson, Aimery De Gramont in Nature Publishing Group (2010)

   Added 2011-11-20 24 readers
5. Pathway-based Diagnostic Biomarker Identification for Post-Traumatic Stress Disorder

   Ruoting Yang, Bernie J Daigle Jr, Linda R Petzold, Francis J Doyle Iii in Blood

   Added 2011-07-20 3 readers
6. A novel functional brain imaging endophenotype of autism: the neural response to facial expression of emotion

   M D Spencer, R J Holt, L R Chura, J Suckling, a J Calder, E T Bullmore, in Translational Psychiatry (2011)

   Added 2011-07-13 29 readers
7. What is a biomarker? Research investments and lack of clinical integration necessitate a review of biomarker terminology and validation schema.

   Adam S Ptolemy, Nader Rifai in Scandinavian journal of clinical and laboratory investigation. Supplementum (2010)

   A continual trend of annual growth can be seen within research devoted to the discovery and validation of disease biomarkers within both the natural and clinical sciences. This expansion of intellectual endeavours was quantified through database…

   Added 2011-06-19 7 readers
8. Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses.

   John P A Ioannidis, Orestis A Panagiotou in JAMA : the journal of the American Medical Association (2011)

   Many biomarkers are proposed in highly cited studies as determinants of disease risk, prognosis, or response to treatment, but few eventually transform clinical practice.

   Added 2011-06-01 69 readers
9. The thin line between hope and hype in biomarker research.

   Patrick M M Bossuyt in JAMA : the journal of the American Medical Association (2011)

   Added 2011-06-01 22 readers
10. Computational biology for cardiovascular biomarker discovery.

    Francisco Azuaje, Yvan Devaux, Daniel Wagner in Briefings in bioinformatics (2009)

    Computational biology is essential in the process of translating biological knowledge into clinical practice, as well as in the understanding of biological phenomena based on the resources and technologies originating from the clinical environment.…

    Added 2011-05-23 16 readers
11. Cancer Biomarkers : Can We Turn Recent Failures into Success ?

    Eleftherios P Diamandis in Journal of the National Cancer Institute (2010)

    Disease biomarkers are used widely in medicine. But very few biomarkers are useful for cancer diagnosis and monitoring. Over the past 15 years, major investments have been made to discover and validate cancer biomarkers. Despite such investments, no…

    Added 2011-05-23 51 readers
12. Bring on the biomarkers.

    George Poste in Nature (2011)

    Added 2011-05-13 48 readers
13. A Bioinformatics Approach to Identify Biomarkers in Oncology Drug Development

    Shujian Wu in Pharmaceutical Research (2007)

    Added 2011-05-12 3 readers
14. A filter-based feature selection approach for identifying potential biomarkers for lung cancer.

    In-Hee Lee, Gerald H Lushington, Mahesh Visvanathan in Journal of clinical bioinformatics (2011)

    ABSTRACT:

    Added 2011-05-11 8 readers
15. Biomarkers and surrogate end points--the challenge of statistical validation.

    Marc Buyse, Daniel J Sargent, Axel Grothey, Alastair Matheson, Aimery de Gramont in Nature reviews. Clinical oncology (2010)

    Biomarkers and surrogate end points have great potential for use in clinical oncology, but their statistical validation presents major challenges, and few biomarkers have been robustly confirmed. Provisional supportive data for prognostic…

    Added 2010-10-19 24 readers
16. Shift in Modern Drug Discovery and Development : The Role ofBiomarkers

    Mark Day, J Lynn Rutkowski, Giora Z Feuerstein in Biomarkers

    Added 2010-10-19 2 readers