New theoretical and practical concepts are presented for considerably enhancing the performance of magnetic resonance imaging (MRI) by means of arrays of multiple receiver coils. Sensitivity encoding (SENSE) is based on the fact that receiver…
Biomedical Physics
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In this study, a novel partially parallel acquisition (PPA) method is presented which can be used to accelerate image acquisition using an RF coil array for spatial encoding. This technique, GeneRalized Autocalibrating Partially Parallel…
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We have developed a high-resolution fluorescence microscopy method based on high-accuracy localization of photoswitchable fluorophores. In each imaging cycle, only a fraction of the fluorophores were turned on, allowing their positions to be…
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Intense radiofrequency power in the form of pulses is applied to an ensemble of spins in a liquid placed in a large static magnetic field H0. The frequency of the pulsed r-f power satisfies the condition for nuclear magnetic resonance, and the…
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A new method has been developed for fast image-based measurements of the transmitted radiofrequency (RF) field. The method employs an actual flip-angle imaging (AFI) pulse sequence that consists of two identical RF pulses followed by two delays of…
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The relative antioxidant functions of thiol-dependent mechanisms and of direct catalytic inactivation of H2O2 were examined using a collection of yeast mutants containing disruptions in single or multiple genes encoding two major enzymatic sources…
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We describe methods for simultaneously acquiring and subsequently combining data from a multitude of closely positioned NMR receiving coils. The approach is conceptually similar to phased array radar and ultrasound and hence we call our techniques…
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Calculation of the centroid of the images of individual fluorescent particles and molecules allows localization and tracking in light microscopes to a precision about an order of magnitude greater than the microscope resolution. The factors that…
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Recent advances in far-field optical nanoscopy have enabled fluorescence imaging with a spatial resolution of 20 to 50 nanometers. Multicolor super-resolution imaging, however, remains a challenging task. Here, we introduce a family of…
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This tutorial is designed to give the reader an understanding of Principal Components Analysis (PCA). PCA is a useful statistical technique that has found application in fields such as face recognition and image compression, and is a common…
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This article is intended to provide an overview of PA imaging, including both OAT and TAT. We will start by providing a description of photoacoustics in soft tissues. After that, we will discuss depth profiling, but only briefly, since good coverage…
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T1, T2, and magnetization transfer (MT) measurements were performed in vitro at 3 T and 37 degrees C on a variety of tissues: mouse liver, muscle, and heart; rat spinal cord and kidney; bovine optic nerve, cartilage, and white and gray matter; and…
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Single particle tracking has seen numerous applications in biophysics, ranging from the diffusion of proteins in cell membranes to the movement of molecular motors. A plethora of computer algorithms have been developed to monitor the sub-pixel…
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Radiobiological studies using heavy charged particles followed closely the development of accelerators to produce beams of ever-increasing energy, driven primarily by the aspirations of physicists and chemists interested in the structure of matter.…
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Single-molecule force spectroscopy has emerged as a powerful tool to investigate the forces and motions associated with biological molecules and enzymatic activity. The most common force spectroscopy techniques are optical tweezers, magnetic…
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Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic cells by defining cellular shape and serving as tracks for intracellular motor proteins. We report the first accurate measurements of the flexural…
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A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers. Dynamic data allocation is used for MCML, hence the number of tissue…
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Magnetic resonance imaging in biochemical and clinical research requires rapid imaging sequences. Time-resolved imaging of heart movement and the acquisition of a three-dimensional image block within the circulation time of a contrast agent bolus…
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The mechanical properties of soft biological tissues are essential to their physiological function and cannot easily be duplicated by synthetic materials. Unlike simple polymer gels, many biological materials-including blood vessels, mesentery…
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The sparsity which is implicit in MR images is exploited to significantly undersample k-space. Some MR images such as angiograms are already sparse in the pixel representation; other, more complicated images have a sparse representation in some…
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Student (Bachelor)Krasnoyarsk, Russia -
Ph.D. StudentThe Hebrew University of Jerusalem -
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