António Domingues's journal articles (663)

Melissa Nassif, Juliana Hoppe, Katiane Santin, Rudimar Frozza, Lauren L Zamin, Ana P Horn, Christianne Salbego (2007) B-Amyloid peptide toxicity in organotypic hippocampal slice culture involves Akt/PKB, GSK-3b, and PTEN, 229-235. In Neurochemistry International.

Download PDF (481.5 KB)

The Journal, Physiology Online, The Physiological Society, Blackwell Publishing (2007) Downloaded from jp.physoc.org by on December 5, 2007. In The Journal of Physiology.

Download PDF (2.45 MB)

Alessia Maracchioni, Antonio Totaro, Daniela F Angelini, Alessandra Di Penta, Tilmann Achsel, Giorgio Bernardi, Maria Teresa Carr (2007) Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration, 142-153. In Journal of Neurochemistry.

Download PDF (678.28 KB)

N-methyl-D-aspartate Receptor Subtypes, Multiple Roles, Neurological Disease (2007) The Neuroscientist. In The Neuroscientist.

Download PDF (193.81 KB)

Brent L Kelly, Adriana Ferreira (2006) -Amyloid-induced Dynamin 1 Degradation Is Mediated by, 28079 -28089. In Journal of Biological Chemistry 281 (38).

Download PDF (649.71 KB)

Ivona Brasnjevic, Harry W M Steinbusch, Christoph Schmitz (2006) Altered gene expression and neuropathology in Alzheimer’s disease, 1081-1083. In Prog Brain Res.

Download PDF (80.21 KB)

Yasuaki Goto, Tetsuhiro Niidome, Akinori Akaike, Takeshi Kihara, Hachiro Sugimoto (2006) Amyloid b-peptide preconditioning reduces glutamate-induced neurotoxicity by promoting endocytosis of NMDA receptor, 259-265. In Biochemical and Biophysical Research Communications.

Download PDF (789.67 KB)

Frank M LaFerla (2006) An array of genes implicated in Alzheimer’s disease, 1078-1080. In Neurobiology of Aging.

Download PDF (66.71 KB)

This Provisional PDF, B M C Genomics, ISSN Article, Article URL, PubMed Central, BioMed Central (2006) BMC Genomics. In BMC Genomics.

Download PDF (2.37 MB)

Yi Na Dong, Hai-Yan Wu, Fu-Chun Hsu, Douglas A Coulter, David R Lynch (2006) Developmental and cell-selective variations in N-methyl-, 206-217. In Journal of Neurochemistry.

Download PDF (851.67 KB)

Jeanne F Loring (2006) Evolution of microarray analysis, 1084-1086. In DNA and Cell Biology.

Download PDF (130.79 KB)

Simona Francisconi, Mara Codenotti, Giulia Ferrari Toninelli, Daniela Uberti, Maurizio Memo (2006) Mitochondrial dysfunction and increased sensitivity to excitotoxicity in mice de cient in DNA mismatch repair, 223-233. In Quality.

Download PDF (315.66 KB)

Pierre Paoletti, Jacques Neyton (2006) NMDA receptor subunits: function and pharmacology, 1-9. In Current Opinion in Pharmacology.

Download PDF (399.9 KB)

Karel Svoboda, Ryohei Yasuda, HHMI Cold Spring Harbor Laboratory Cold Spring Harbor, New York, North Carolina (2006) Principles of Two-Photon Excitation Microscopy and Its Applications to Neuroscience, 823-839. In Microscopy.

Download PDF (696.51 KB)

Carsten Schmidt, Markus Werner, Michael Hollmann (2006) Revisiting the Postulated “Unitary Glutamate Receptor”: Electrophysiological and Pharmacological Analysis in Two Heterologous Expression Systems Fails to Detect Evidence for Its Existence, 119-129. In Mol Pharmacol 69 (1).

Download PDF (449.69 KB)

Wei-Yi Ong, Leonid G Motin, Mitchell A Hansen, Leonora S Dias, Chantal Ayrout, Maxwell R Bennett, Vladimir J Balcar, Both NMDA, G Increasing, J Neurosci, INTRODUCTION The N-methyl-D-aspartate, The NMDA (2006) Subclass of P 2 receptors are ligand-gated Ca 2؉ -selective channels and, since the increased in ux of Ca 2؉ into neurons has been linked to neurotoxicity, simultaneous inhibition of P, 627-638. In In Vivo 638 (November 1996).

Download PDF (302.25 KB)

Emmanuel Brouillet, Carine Jacquard, Nicolas Bizat, David Blum (2005) 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington’s disease, 1521-1540. In Journal of Neurochemistry.

Download PDF (264.63 KB)

N Brustovetsky, R LaFrance, K J Purl, T Brustovetsky, C D Keene, W C Low, J M Dubinsky (2005) Age-Dependent Changes in the Calcium Sensitivity of Striatal Mitochondria in Mouse Models of Huntington’s Disease, 1-10. In Journal of Neurochemistry.

Download PDF (283.81 KB)

Gregory J Brewer, Nicole G Capps, John R Torricelli (2005) Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in hippocampal neurons in response to glutamate and beta-amyloid, 426-437. In Technology.

Download PDF (326.79 KB)

Alexandra Du, Alexis Brice, Patrick Aebischer, Nicole De Emilie Colin, Etienne Re, Saudou Sandrine Humbert (2005) Akt is altered in an animal model of Huntington’s disease and in patients ´, 1478-1488. In European Journal of Neuroscience 21 (January).

Download PDF (735.41 KB)

Frank M LaFerla, Salvatore Oddo (2005) Alzheimer’s disease: Ab, tau and synaptic dysfunction. In Trends in Molecular Medicine 11 (4).

Download PDF (2.62 MB)

Journal Club, Sylvain Lesne, Linda Kotilinek (2005) Amyloid Plaques and Amyloid- ␤ Oligomers: An Ongoing Debate, 9319 -9320. In Journal of Neuroscience 25 (41).

Download PDF (72.29 KB)

Douglas R Green, Science Center Drive San Diego (2005) Apoptotic Pathways: Ten Minutes to Dead, 671-674. In Cell.

Download PDF (109.9 KB)

Hemachandra Reddy, Flint Beal (2005) Are mitochondria critical in the pathogenesis of Alzheimer’s disease?, 618 - 632. In Brain Research Reviews.

Download PDF (231.03 KB)

Cordian Beyer, Malgorzata Kajta, Andreas Trotter, Wladyslaw Lason (2005) Article in press. In Developmental Brain Research.

Download PDF (918.12 KB)

Daniel R Binder, William H Dunn Jr, Russell H Swerdlow (2005) Article in press, 1-11. In Review Literature And Arts Of The Americas.

Download PDF (187.22 KB)

Jacqueline Shehadeh, Herman B Fernandes, Melinda M Zeron Mullins, Rona K Graham, Blair R Leavitt, Michael R Hayden, Lynn A Raymond (2005) Article in press. In Neurobiology of Disease.

Download PDF (575.93 KB)

Debra Boyd-Kimball, Alessandra Castegna, Rukhsana Sultana, Fai Poon, Robin Petroze, Bert C Lynn, Jon B Klein, Allan Butterfield (2005) Article in press, 14 -16. In Brain Research.

Download PDF (698.57 KB)

Eileen McGowan, Fiona Pickford, Jungsu Kim, Luisa Onstead, Jason Eriksen, Cindy Yu, Lisa Skipper, Paul Murphy, Jenny Beard, Pritam Das, Karen Jansen, Michael DeLucia, Wen-Lang Lin, Georgia Dolios, Rong Wang, Christopher B Eckman, Dennis W Dickson, Mike Hutton, John Hardy, Todd Golde, Medicine Jacksonville, Medicine New York, New York, Aging National Institutes, Health Bethesda, Moreover APP, Familial British, Danish Dementia, The BRI-A (2005) A␤42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice, 191-199. In Neuron.

Download PDF (558.88 KB)

K E Y Words (2005) BDNF Enhancement of Postsynaptic NMDA Receptors Is Blocked by Ethanol, 52-57. In Neuroreport 57 (September 2004).

Download PDF (149.61 KB)

Susan A Green (2005) Biotechnology, the brain and the future. In Trends in biotechnology 23 (1).

Download PDF (1.25 MB)

(2005) Blocking a path to cell death, 2005-2005. In Neuroscience 6 (August).

Download PDF (159.51 KB)

Evan Elliott, Roee Atlas, Aya Lange, Irith Ginzburg (2005) Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3Kinase signalling mechanism, 1081-1089. In European Journal of Neuroscience.

Download PDF (460.27 KB)

J B C Papers, Angelo Demuro, Erene Mina, Rakez Kayed, Saskia C Milton, Ian Parker, Charles G Glabe, Molecular Biology, California Irvine, Charles Glabe, McGaugh Hall (2005) Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers, 1-16. In Signals.

Download PDF (629.75 KB)

Mayana Zatz, Alessandra Starling (2005) Calpains and Disease, 2413-2423. In MEDICINA.

Download PDF (535.71 KB)

William G M Janssen, Prabakhar Vissavajjhala, Ginelle Andrews, Thomas Moran, Patrick R Hof, John H Morrison (2005) Cellular and synaptic distribution of NR2A and NR2B in macaque monkey and rat hippocampus as visualized with subunit-specific monoclonal antibodies, 28-44. In Experimental Neurology.

Download PDF (919.05 KB)

B FOGAL, J TRETTEL, T F ULIASZ, E S Levine, S J Hewett (2005) Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death, 929 -942. In Readings.

Download PDF (367.08 KB)

E RIBE, A Rubio, F Lim, M A MOR, M E Z RAMOS, I Ferrer, M T G ISLA, J Avila (2005) Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation, 339 -347. In Neuroscience.

Download PDF (616.77 KB)

Fan-Yan Wei, Kazuhito Tomizawa, Toshio Ohshima, Akiko Asada, Taro Saito, Chan Nguyen, James A Bibb, Koichi Ishiguro, Ashok B Kulkarni, Harish C Pant, Katsuhiko Mikoshiba, Hideki Matsui, Shin-ichi Hisanaga (2005) Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability, 1-11. In Journal of Neurochemistry.

Download PDF (408.44 KB)

K Sonkusare, L Kaul, P Ramarao (2005) Dementia of Alzheimer’s disease and other neurodegenerative disorders—memantine, a new hope, 1-17. In Pharmacological Research.

Download PDF (371.66 KB)

P Ferrera, C Arias (2005) Differential effects of COX inhibitors against b-amyloid-induced neurotoxicity in human neuroblastoma cells, 589-596. In Neurochemistry International.

Download PDF (289.15 KB)

Myung Jong Kim, ANTHONE W DUNAH, Yu Tian Wang, Morgan Sheng, The Picower Center, Technology Cambridge, Brain Research Centre, Medicine Vancouver Hospital, British Columbia Vancouver, A-containing NMDARs, B-containing NMDARs, A- NMDARs, The ERK, NMDAR-dependent ERK, GTPase Ras, The RasGEF RasGRF, Altered AMPAR, NMDAR-dependent LTP (2005) Differential Roles of NR2A- and NR2B-Containing NMDA Receptors in Ras-ERK Signaling and AMPA Receptor Trafficking, 745-760. In Neuron.

Download PDF (6.92 MB)

Neena Kushwaha, Yi Zhang, Hossein Aleyasin, Steven M Callaghan, Ruth S Slack, Paul R Albert, Inez Vincent, David S Park (2005) Differential Roles of Nuclear and Cytoplasmic Cyclin-Dependent Kinase 5 in Apoptotic and Excitotoxic Neuronal Death, 8954 - 8966. In Neurobiology of Disease 25 (39).

Download PDF (967.11 KB)

Viktor Szegedi, BOTOND PENKE (2005) Divergent effects of Ah1–42 on ionotropic glutamate receptor-mediated responses in CA1 neurons in vivo, 120 - 126. In Brain Research.

Download PDF (339.06 KB)

Jerry E Chipuk, Douglas R Green (2005) Do inducers of apoptosis trigger caspase-independent cell death?, 268-275. In Cell 6 (March).

Download PDF (270.74 KB)

Christina Unger, Monika M Hedberg, Tamanna Mustafiz, Marie M Svedberg, Agneta Nordberg (2005) Early changes in AB levels in the brain of APPswe transgenic mice—Implication on synaptic density, A7 neuronal nicotinic acetylcholine- and N-methyl-, 218 - 227. In Mol Cell Neurosci.

Download PDF (768.27 KB)

Rodney A Velliquette, Robert Vassar (2005) Energy Inhibition Elevates ␤ -Secretase Levels and Activity and Is Potentially Amyloidogenic in APP Transgenic Mice: Possible Early Events in Alzheimer’s Disease Pathogenesis, 10874 -10883. In In Vivo 25 (47).

Download PDF (522.79 KB)

(2005) Exercise Your Amyloid, 2002-2004. In Dev Cell.

Download PDF (44.33 KB)

Francesco Misiti, Beatrice Sampaolese, Michela Pezzotti, Stefano Marini, Massimo Coletta, Lia Ceccarelli, Bruno Giardina, Maria Elisabetta Clementi (2005) Francesco Misiti, 575-583. In Neurochemistry International.

Download PDF (307.83 KB)

Laszlo Kiss, Gong Cheng, Bohumil Bednar, Rodney A Bednar, Paul B Bennett, Stefanie A Kane, Charles J McIntyre, John A McCauley, Kenneth S Koblan (2005) In vitro characterization of novel NR2B selective NMDA receptor antagonists, 453-464. In Molecular Biology.

Download PDF (477.72 KB)

Patrizia De Sarno, Gautam N Bijur, Anna A Zmijewska, Xiaohua Li, Richard S Jope (2005) In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors. In Neurobiology of Aging.

Download PDF (663.88 KB)

Dalma Kurko, Zsolt Szombathelyi La (2005) Inducible expression and pharmacological characterization of recombinant rat NR1a/NR2A NMDA receptors ´ *,, 369-379. In Neurochemistry International.

Download PDF (309.46 KB)

Paula I Moreira, Maria S Santos, Cristina Sena, Raquel Seic, Catarina R Oliveira (2005) Insulin protects against amyloid B-peptide toxicity in brain mitochondria of diabetic rats, 628 - 637. In Control.

Download PDF (284.85 KB)

Brief Communication, Sven Berberich, Pradeep Punnakkal, Vidar Jensen, Verena Pawlak, Peter H Seeburg, Georg Ko (2005) Lack of NMDA Receptor Subtype Selectivity for Hippocampal Long-Term Potentiation, 6907- 6910. In Nat Rev Neurosci 25 (29).

Download PDF (243.88 KB)

M T JENSEN, M D MOTTIN, J R CRACCHIOLO, R E LEIGHTY, G W Arendash (2005) Lifelong immunization with human, 667- 684. In Neuroscience.

Download PDF (716.85 KB)

Izumi Nomura, Nobuo Kato, Toru Kita, Hajime Takechi (2005) Mechanism of impairment of long-term potentiation by amyloid ␤ is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons, 1-6. In Neuroscience Letters.

Download PDF (240.6 KB)

A Yu, E Kushnareva, A A Starkov (2005) Mitochondrial Metabolism of Reactive Oxygen Species, 200-214. In Text 70 (2).

Download PDF (349.41 KB)

A Yu, E Kushnareva, A A Starkov (2005) Mitochondrial Metabolism of Reactive Oxygen Species, 200-214. In Text 70 (2).

Download PDF (349.41 KB)

Kate M Webber, Mark A Smith, Hyoung-gon Lee, Peggy L Harris, Paula Moreira, George Perry, Xiongwei Zhu (2005) Mitogen- and Stress-Activated Protein Kinase 1: Convergence of the ERK and p38 Pathways in Alzheimer’s Disease, 554 -560..

Download PDF (226.24 KB)

David M Thomas, Donald M Kuhn (2005) MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity, 190 - 198. In Laboratory Animals.

Download PDF (346.51 KB)

Christopher J Hatton, Pierre Paoletti, Neurobiologie CNRS UMR, Ecole Normale Sup, Paris France (2005) Modulation of Triheteromeric NMDA Receptors by N-Terminal Domain Ligands, 261-274. In Neuron.

Download PDF (434.42 KB)

Slavica Krantic, Naguib Mechawar (2005) Molecular basis of programmed cell death involved in neurodegeneration ´. In Trends in Neurosciences 28 (12).

Download PDF (862.02 KB)

Edwin H Jacobs, George Wardeh, August B Smit, Anton N M Schoffelmeer (2005) Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core, 27 - 30. In European Journal of Pharmacology.

Download PDF (112.14 KB)

Nature Publishing Group, Whether LTP (2005) Natural oligomers of the amyloid-β protein specifically disrupt cognitive function, 79-84. In NATURE NEUROSCIENCE 8 (1).

Download PDF (251.78 KB)

Kohtaro Kato, Sei-itsu Murota (2005) NMDA receptor stimulation in the absence of extracellular Ca 2+ potentiates Ca 2+ influx-dependent cell death system, 177 - 187..

Download PDF (328.18 KB)

Andres Barria, Roberto Malinow Cold Spring Harbor Laboratory Cold Spring Harbor, New York (2005) NMDA Receptor Subunit Composition Controls Synaptic Plasticity by Regulating Binding to CaMKII, 289-301. In October.

Download PDF (746.18 KB)

Byoung-Il Bae, Hong Xu, Shuichi Igarashi, Masahiro Fujimuro, Nishant Agrawal, Yoichi Taya, Diane Hayward, Timothy H Moran, Craig Montell, Christopher A Ross, Solomon H Snyder, Akira Sawa, Biological Chemistry, Behavioral Sciences, North Wolfe Street Baltimore, Mutant Htt (2005) P53 Mediates Cellular Dysfunction and Behavioral Abnormalities in Huntington’s Disease, 29-41. In Neuron.

Download PDF (712.16 KB)

Marta Artal-Sanz, Nektarios Tavernarakis (2005) Proteolytic mechanisms in necrotic cell death and neurodegeneration, 3287-3296. In FEBS Letters.

Download PDF (230.52 KB)

Yasunobu Murata, Tomoko Doi, Hisaaki Taniguchi, Yoshinori Fujiyoshi (2005) Proteomic analysis revealed a novel synaptic proline-rich membrane protein (PRR7) associated with PSD-95 and NMDA receptor, 183-191. In Biochemical and Biophysical Research Communications.

Download PDF (993.35 KB)

Yi Nong, Surojit Paul, Timothy Moran, Eun Young Choi, Paul Greengard (2005) Regulation of NMDA receptor traf cking by amyloid-b, 1051-1058. In Nature Neuroscience 8 (8).

Download PDF (358.25 KB)

RESEARCH ARTICLE Andrew P Mallon, Yves P Auberson, Trevor W Stone (2005) Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-, 374-383. In Exp Brain Res.

Download PDF (278.74 KB)

Masahiro Fukaya, Yasunori Hayashi, Masahiko Watanabe (2005) SHORT COMMUNICATION NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons, 1432-1436. In European Journal of Neuroscience.

Download PDF (267.12 KB)

F Roselli, M Tirard, J Lu, P Hutzler, P Lamberti, P Livrea, M Morabito, O F X Almeida (2005) Soluble ␤ -Amyloid 1– 40 Induces NMDA-Dependent Degradation of Postsynaptic Density-95 at Glutamatergic Synapses, 11061-11070. In Neurobiology of Disease 25 (48).

Download PDF (468.49 KB)

Zhenyue Hao, Gordon S Duncan, Chia-Che Chang, Andrew Elia, Min Fang, Andrew Wakeham, Hitoshi Okada, Thomas Calzascia, YingJu Jang, Annick You-Ten, Wen-Chen Yeh, Pamela Ohashi, Xiaodong Wang, Tak W Mak, Breast Cancer Research, Toronto Toronto, Texas Southwestern Medical Center, Dallas Dallas, Antiapoptotic Bcl- (2005) Specific Ablation of the Apoptotic Functions of Cytochrome c Reveals a Differential Requirement for Cytochrome c and Apaf-1 in Apoptosis, 579-591. In Cell.

Download PDF (1010.49 KB)

Kevin Erreger, Shashank M Dravid, Tue G Banke, David J A Wyllie, Stephen F Traynelis (2005) Subunit-speci c gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling pro les, 345-358. In Society.

Download PDF (546.23 KB)

Yong Liu, Guang-Yi Zhang, Jing-Zhi Yan, Tian-Le Xu (2005) Suppression of Pyk2 attenuated the increased tyrosine phosphorylation of NMDA receptor subunit 2A after brain ischemia in rat hippocampus, 55-58. In Neuroscience Letters.

Download PDF (184.94 KB)

Yong Liu, Guang-Yi Zhang, Jing-Zhi Yan, Tian-Le Xu (2005) Suppression of Pyk2 attenuated the increased tyrosine phosphorylation of NMDA receptor subunit 2A after brain ischemia in rat hippocampus, 4-7. In Neuroscience Letters.

Download PDF (189.32 KB)

Rudolph E Tanzi, Alois Alzheimer (2005) Tangles and Neurodegenerative Disease — A Surprising Twist, 1853-1855. In MEDICINA.

Download PDF (438.75 KB)

Multifaceted Protein, Part II (2005) The Aβ Hypothesis: Leading Us to Rationally-Designed Therapeutic Strategies for the Treatment or Prevention of Alzheimer Disease, 84-87. In Eur J Biochem.

Download PDF (76.88 KB)

The Bad Seed (2005) The Bad Seed in Alzheimer’s Disease, 167-168. In Neuron.

Download PDF (40.17 KB)

The Power, Dark Side, Disease Protein, Deadly Alliance (2005) The Power of the Dark Side: Huntington’s Disease Protein and p53 Form a Deadly Alliance, 8-10. In Neuron.

Download PDF (74.4 KB)

Sandra M Cardoso, Catarina R Oliveira (2005) The role of calcineurin in amyloid-h-peptides-mediated cell death, 1 - 7. In Cell.

Download PDF (431.83 KB)

NEWSVIEWS (2005) The synaptic Aβ hypothesis of Alzheimer disease, 2004-2006. In NATURE NEUROSCIENCE 8 (8).

Download PDF (221.72 KB)

Bai Lu, Petti T Pang, Newton H Woo (2005) The yin and yang of neurotrophin action, 603-614. In Neuroscience 6 (August).

Download PDF (840.14 KB)

Thomas D Corso, German Torres, Christopher Goulah, Indrajit Roy, Angelo S Gambino, John Nayda, Timothy Buckley, Ewa K Stachowiak, Earl J Bergey, Haridas Pudavar, Purnendu Dutta, David C Bloom, William J Bowers, Michal K Stachowiak (2005) Transfection of tyrosine kinase deleted FGF receptor-1 into rat brain substantia nigra reduces the number of tyrosine hydroxylase expressing neurons and decreases concentration levels of striatal dopamine, 361 - 366. In Growth.

Download PDF (333.68 KB)

Rudolph E Tanzi, Lars Bertram Genetics, From Alois Alzheimer, George Glenner, Introduction Perhaps, Alois Alzheimer, Emil Kraepelin, D Studies, S Taken, From A D Pathology, Genetics The (2005) Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective, 545-555. In Cell.

Download PDF (257.45 KB)

Susan M Goebel, Rachel M Alvestad, Steven J Coultrap, Michael D Browning (2005) Tyrosine phosphorylation of the N-methyl-d-aspartate receptor is enhanced in synaptic membrane fractions of the adult rat hippocampus, 65 - 79. In Molecular Brain Research.

Download PDF (550.78 KB)

Liqi Tong, Robert Balazs, Phillip L Thornton, Carl W Cotman (2004) -Amyloid Peptide at Sublethal Concentrations Downregulates Brain-Derived Neurotrophic Factor Functions in Cultured Cortical Neurons, 6799 - 6809. In Brain Res 24 (30).

Download PDF (380.23 KB)

Qinwen Wang, Michael J Rowan, Roger Anwyl (2004) -Amyloid-Mediated Inhibition of NMDA Receptor- Dependent Long-Term Potentiation Induction Involves Activation of Microglia and Stimulation of Inducible Nitric Oxide Synthase and Superoxide, 6049 - 6056. In Neuroscience 24 (27).

Download PDF (359.7 KB)

Sandra Isabel Vieira, Sandra Rebelo (2004) A Model System to Study Intracellular Trafficking and Processing of the Alzheimer’s Amyloid Precursor Protein, 196-204.

Download PDF (411.84 KB)

Oliver Wirths, Gerd Multhaup, Thomas A Bayer (2004) A modi ed b-amyloid hypothesis: intraneuronal accumulation of the b-amyloid peptide – the rst step of a fatal cascade, 513-520. In Journal of Neurochemistry.

Download PDF (151.48 KB)

Lu Yang, Limin Mao, Qingsong Tang, Shazia Samdani, Zhenguo Liu, John Q Wang (2004) A Novel Ca, 10846 -10857. In Regulation 24 (48).

Download PDF (595.34 KB)

Dirk Lochmann, Andreas Zimmer (2004) A practical note on the use of cytotoxicity assays. In International Journal of Pharmaceutics.

Download PDF (273.2 KB)

Huangui Xiong, Laura McCabe, Joseph Costello, Eric Anderson, Gregory Weber, Tsuneya Ikezu (2004) Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyte-derived macrophages: implications for the pathogenesis of Alzheimer’s disease, 905-911. In In Vitro.

Download PDF (171.15 KB)

Brian Dalby, Sharon Cates, Adam Harris, Elise C Ohki, Mary L Tilkins, Paul J Price, Valentina C Ciccarone (2004) Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications, 95-103. In Methods.

Download PDF (533.65 KB)

Philip Scheltens (2004) Advances in the early detection of Alzheimer’s disease, 34-41. In NEURODEGENERATION.

Download PDF (1.32 MB)

Alex Verkhratsky, Mark P Mattson, Emil C Toescu (2004) Aging in the mind, 10-11. In Trends in Neurosciences 27 (10).

Download PDF (62.88 KB)

Finkbeiner Now (2004) Allies in the fight against neurodegeneration, 805-810. In Neuroscience 5 (December).

Download PDF (1.01 MB)

Mohammad Tabish, Maharaj K Ticku (2004) Alternate splice variants of mouse NR2B gene, 339-343. In Neurochemistry International.

MARGARIDA FARDILHA, WENJUAN WU, SARA FIDALGO, CRISTINA SOUSA, CATARINA MOTA, Signal Transduction Laboratory, Cell Biology, Neuroscience Laboratory, INTRODUCTION Recently (2004) Alternatively Spliced Protein Variants as Potential Therapeutic Targets for Male Infertility and Contraception, 468-478. In DNA sequence.

Download PDF (195.98 KB)

MARGARIDA FARDILHA, WENJUAN WU, SARA FIDALGO, CRISTINA SOUSA, CATARINA MOTA, Signal Transduction Laboratory, Cell Biology, Neuroscience Laboratory, INTRODUCTION Recently (2004) Alternatively Spliced Protein Variants as Potential Therapeutic Targets for Male Infertility and Contraception, 468-478. In DNA sequence.

Download PDF (250.8 KB)

N E U OBIOLOGI, EXPE IMENT LIS, Alexei R Koudinov, Temirbolat T Berezov (2004) Alzheimer’s amyloid-beta (Ab) is an essential synaptic protein, not neurotoxic junk, 71-79.

Download PDF (122.53 KB)

Greta Ann Herin, Elias Aizenman (2004) Amino terminal domain regulation of NMDA receptor function, 101 - 111. In European Journal of Pharmacology.

Download PDF (237.74 KB)

Uta Keil, Astrid Bonert, Celio A Marques, Isabel Scherping, Joanna B Strosznajder, Franz Mu, Christian Haass, Christian Czech, Laurent Pradier, Walter E Mu, Anne Eckert (2004) Amyloid ␤ -induced Changes in Nitric Oxide Production and Mitochondrial Activity Lead to Apoptosis*, 50310 -50320. In Molecular Biology 279 (48).

Download PDF (700.78 KB)

Chianping Ye, Dominic M Walsh, Dennis J Selkoe, Dean M Hartley (2004) Amyloid ␤-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-d-aspartate (NMDA) versus non-NMDA receptor/channel activation, 320-325. In Neuroscience Letters.

Download PDF (258.67 KB)

Tianbing Liu, George Perry, Hsien W Chan, Giuseppe Verdile, Ralph N Martins, Mark A Smith, Craig S Atwood (2004) Amyloid-b-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression, 1-10. In Journal of Neurochemistry.

Download PDF (174.47 KB)

Bart De Strooper Vale (2004) Amyloid-beta precursor protein processing in neurodegeneration ´, 582-588. In Current Opinion in Neurobiology.

Download PDF (188.25 KB)

(2004) Apoptosis pathways and drug targets, 1104-1104. In Int J Obes Relat Metab Disord.

Download PDF (321.01 KB)

Hongmin Wang, Seong-Woon Yu, David W Koh, Jasmine Lew, Carmen Coombs, William Bowers, Howard J Federoff, Guy G Poirier, Ted M Dawson, Valina L Dawson (2004) Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death, 10963-10973. In Brain 24 (48).

Download PDF (649.96 KB)

Barbara Tru, Matthew Wood (2004) Applications of nucleic acid technology in the CNS, 257-265. In Journal of Neurochemistry.

Download PDF (153.8 KB)

GENE DELIVERY (2004) Article in press. In Journal of Controlled Release.

Download PDF (620.69 KB)

Martin Citron (2004) B-Secretase inhibition for the treatment of Alzheimer’s disease – promise and challenge. In Trends in Pharmacological Sciences 25 (2).

Download PDF (372.67 KB)

Masuo Ohno, Evgeny A Sametsky, Linda H Younkin, Holly Oakley, Steven G Younkin, Martin Citron, Robert Vassar, John F Disterhoft, Medicine Chicago, Mayo Clinic Jacksonville Jacksonville, Neuroscience Amgen Inc, Thousand Oaks (2004) BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer’s Disease, 27-33. In Neuron.

Download PDF (226.08 KB)

Shih-Chu Kao, Anna M Krichevsky, Kenneth S Kosik, Li-Huei Tsai (2004) BACE1 Suppression by RNA Interference in Primary Cortical Neurons*, 1942-1949. In Molecular Biology 279 (3).

Download PDF (624.21 KB)

Jr Lansbury (2004) Back to the future: the ‘old-fashioned’ way to new medications for neurodegeneration, 51-57. In NEURODEGENERATION.

Download PDF (775.1 KB)

Thomas Ladewig, Stefan Fellner, Eberhart Zrenner, Konrad Kohler, Elke Guenther (2004) BDNF regulates NMDA receptor activity in developing retinal ganglion cells, 5-9. In Time 15 (16).

Download PDF (229.23 KB)

Amanda J Mishizen-Eberz, Robert A Rissman, Troy L Carter, Milos D Ikonomovic, Barry B Wolfe, David M Armstrong (2004) Biochemical and molecular studies of NMDA receptor subunits NR1/ 2A/2B in hippocampal subregions throughout progression of Alzheimer’s disease pathology, 80 - 92. In Neurobiology of Disease.

Download PDF (978.95 KB)

Egbert K O Kruithof (2004) BMC Molecular Biology, 1-15. In BMC Molecular Biology.

Download PDF (1.03 MB)

Petri Kerokoski, Tiina Suuronen, Antero Salminen, Hilkka Soininen, Tuula Pirttil (2004) Both N-methyl-d-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons, 181-185. In Neuroscience Letters.

Download PDF (163 KB)

Kuo Wu, Guo-wei Len, Geoff McAuliffe, Jessica P Tai, Fei Xu, Ira B Black (2004) Brain-derived neurotrophic factor acutely enhances tyrosine phosphorylation of the AMPA receptor subunit GluR1 via NMDA receptor-dependent mechanisms, 178 - 186. In Molecular Brain Research.

Download PDF (701.98 KB)

Yigong Shi, New Jersey, The Induced Proximity, Death-Inducing Signaling Complex (2004) Caspase Activation: Revisiting the Induced Proximity Model, 855-858. In Cell.

Download PDF (170.91 KB)

HIGHLIGHT ADVISORS ERIK D E CLERCQ KATHOLIEKE UNIVERSITEIT LEUVEN, U K YOSHIJI FUJITA CLINICAL PROTEOME CENTER, U S A FRANZ HEFTI RINAT NEUROSCIENCE CORPORATION, Palo Alto, U S A MADS KROGSGAARD THOMSEN NOVO NORDISK, U S A CHRISTOPHER LIPINSKI PFIZER GLOBAL RESEARCHDEVELOPMENT, U S A TOMI SAWYER ARIAD PHARMACEUTICALS, U S A JANET WOODCOCK FOOD (2004) Chemical engineering, 7-10. In Discovery 3 (October).

Download PDF (312.66 KB)

Shifang Zhang, Martin Chalfie, New York (2004) Combinatorial Marking of Cells and Organelles with Reconstituted Fluorescent Proteins, 137-144. In October.

Download PDF (1.34 MB)

Synaptic Strength (2004) Controlling the Ups and Downs of Synaptic Strength, 973-974. In Science.

Download PDF (143.71 KB)

Download PDF (474.25 KB)

Ella Bossy-Wetzel, MARIA V TALANTOVA, Wilson D Lee, Marion N Scho, Anne Harrop, Emily Mathews, Thomas Go, Jiahuai Han, Mark H Ellisman, Guy A Perkins, Stuart A Lipton, National Center, San Diego La Jolla, K Kikuchi (2004) Crosstalk between Nitric Oxide and Zinc Pathways to Neuronal Cell Death Involving Mitochondrial Dysfunction and p38-Activated K ؉ Channels, 351-365. In Neuron.

Download PDF (916.83 KB)

Valina L Dawson, Ted M Dawson (2004) Deadly Conversations: Nuclear-Mitochondrial Cross-Talk. In Journal of Bioenergetics and Biomembranes 36 (4).

Download PDF (409.91 KB)

Dominic M Walsh, Dennis J Selkoe, Neurology Brigham (2004) Deciphering the Molecular Basis of Memory Failure in Alzheimer’s Disease, 181-193. In Neuron.

Download PDF (289.51 KB)

Matthew R Hynd, Heather L Scott, Peter R Dodd (2004) Differential expression of N-methyl-, 913-919. In Journal of Neurochemistry.

Download PDF (250.28 KB)

Takashi Iwamoto, Yasue Yamada, Kei Hori, Yoshifumi Watanabe, Kenji Sobue, Makoto Inui (2004) Differential modulation of NR1-NR2A and NR1-NR2B subtypes of NMDA receptor by PDZ domain-containing proteins, 100-108. In Journal of Neurochemistry.

Download PDF (709.5 KB)

Peter V Massey, Benjamin E Johnson, Peter R Moult, Yves P Auberson, Malcolm W Brown, Elek Molnar, Graham L Collingridge, Zafar I Bashir (2004) Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression, 7821-7828. In Neuroscience 24 (36).

Download PDF (423.27 KB)

Peter V Massey, Benjamin E Johnson, Peter R Moult, Yves P Auberson, Malcolm W Brown, Elek Molnar, Graham L Collingridge, Zafar I Bashir (2004) Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression, 7821-7828. In Neuroscience 24 (36).

Download PDF (423.27 KB)

Ke Ning, Lin Pei, Mingxia Liao, Baosong Liu, Yunzhou Zhang, Wen Jiang, John G Mielke, Lei LI, Yonghong Chen, Youssef H El-Hayek, Michael G Fehlings, Xia Zhang, Fang Liu, James Eubanks, Qi Wan (2004) Dual Neuroprotective Signaling Mediated by Downregulating Two Distinct Phosphatase Activities of PTEN, 4052- 4060. In Nat Neurosci 24 (16).

Download PDF (587.05 KB)

Grace E Stutzmann, Antonella Caccamo, Frank M LaFerla, Ian Parker (2004) Dysregulated IP 3 Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer’s-Linked Mutation in, 508 -513. In Neurobiology of Disease 24 (2).

Download PDF (309.76 KB)

NMDA Receptor Subtypes, Hippocampal Synaptic Plasticity (2004) Echnical omment, 6-7. In Science 305 (September).

Download PDF (77.22 KB)

(2004) Echnical omment, 2004-2004. In Science 305 (August).

Download PDF (54.22 KB)

Piotr Lewczuk, Hermann Esselmann, Mirko Bibl, Sabine Paul, Jana Svitek, Johannes Miertschischk, Robert Meyrer, Alexandr Smirnov, Juan Manuel Maler, Christian Klein, Markus Otto, Stefan Bleich, Wolfgang Sperling, Johannes Kornhuber, Jens Wiltfang (2004) Electrophoretic separation of amyloid, 3336-3343. In Molecular Neurobiology.

Download PDF (162.82 KB)

Elisabete Ferreiro, Catarina R Oliveira (2004) Elisabete Ferreiro, Catarina R. Oliveira, and Cla ´ udia Pereira *, 872- 880. 880 (May).

Download PDF (133.28 KB)

M Wittmann, P Bengtson, H Bading (2004) Extrasynaptic NMDA receptors: mediators of excitotoxic cell death.

Download PDF (1.06 MB)

Stuart A Lipton (2004) Failures and Successes of NMDA Receptor Antagonists: Molecular Basis for the Use of Open-Channel Blockers like Memantine in the Treatment of Acute and Chronic Neurologic Insults, 101-110. In Neurotherapeutics 1 (January).

Download PDF (675.54 KB)

Sandra Almeida, Catarina R Oliveira, Cristina Rego (2004) FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures, 435 - 444. In Neurobiology of Disease.

Download PDF (626.33 KB)

Gustavo Barja (2004) Free radicals and aging. In Trends in Neurosciences 27 (10).

Download PDF (161.23 KB)

Functional Inhibition, Aspartate Receptors Expressed, Xenopus Oocytes, Subunit Effects (2004) Functional Inhibition by Methadone of N-Methyl-. In Life Sciences.

Download PDF (194.56 KB)

Gonzalo Bustos, Jorge Abarca, Jorge Campusano, Victor Bustos, Viviana Noriega, Esteban Aliaga (2004) Functional interactions between somatodendritic dopamine release, glutamate receptors and brain-derived neurotrophic factor expression in mesencephalic structures of the brain, 126 - 144. In Cell.

Download PDF (388.77 KB)

Anna Kowalska, Danuta Pruchnik-Woli, Jolanta Florczak, Renata Modestowicz, Wojciech Kozubski, Grzegorz Rossa (2004) Genetic study of familial cases of Alzheimer’s disease. 51 (1).

Download PDF (528.74 KB)

This Provisional PDF, Genetic Vaccines, Frank Schakowski, Peter Buttgereit, Martin Mazur, Angela Marten, Bjorn Schottker, Marcus Gorschluter, Ingo G H Schmidt-Wolf, Research Submission, Article URL, PubMed Central, BioMed Central (2004) Genetic Vaccines and Therapy. In Genetic Vaccines and Therapy.

Download PDF (759.2 KB)

Matthew R Hynd, Heather L Scott, Peter R Dodd (2004) Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease, 583-595. In Neurochemistry International.

Download PDF (278.61 KB)

Stephen Kelly, Heng Zhao, Guo Hua Sun, Danye Cheng, Yanli Qiao, Jian Luo, Kathleen Martin, Gary K Steinberg, Stephen D Harrison, Midori A Yenari (2004) Glycogen synthase kinase 3h inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia, 378 - 386. In Experimental Neurology.

Download PDF (351.58 KB)

Yi Na Dong, Elisa A Waxman, David R Lynch (2004) Interactions of Postsynaptic Density-95 and the NMDA Receptor 2 Subunit Control Calpain-Mediated Cleavage of the NMDA Receptor, 11035-11045. 24 (49).

Download PDF (421.27 KB)

M Ullian, B Barkis, S Chen, S Diamond, A Barres (2004) Invulnerability of retinal ganglion cells to NMDA excitotoxicity, 544 - 557. In Mol Cell Neurosci.

Download PDF (577.52 KB)

Paula I Moreira, Quan Liu, Kazuhiro Honda, Mark A Smith, Maria S Santos, Catarina R Oliveira (2004) Is intraneuronal amyloid, 433-434. In J Biol Chem.

Download PDF (24.52 KB)

This Provisional PDF, Translational Medicine, Jyoti Choudhuri, Manjit Gill-Sharma, Research Submission, Article URL, PubMed Central, BioMed Central (2004) Journal of Translational Medicine. In Journal of Translational Medicine.

Download PDF (241.9 KB)

Bohumil Bednar, Michael E Cunningham, Laszlo Kiss, Gong Cheng, John A McCauley, Nigel J Liverton, Kenneth S Koblan (2004) Kinetic characterization of novel NR2B antagonists using uorescence detection of calcium ux, 247-255. In Journal of Neuroscience Methods.

Download PDF (217.22 KB)

MARGARIDA FARDILHA, WENJUAN WU, CATARINA MOTA, SARA FIDALGO (2004) Laboratório de Transdução de Sinais e 2 Laboratório de Neurociências, 17-25. In Yeast.

Download PDF (174.42 KB)

Nilou Arden, Michael J Betenbaugh (2004) Life and death in mammalian cell culture: strategies for apoptosis inhibition. In Trends in biotechnology 22 (4).

Download PDF (253.22 KB)

Carlos A Saura, Se-Young Choi, Vassilios Beglopoulos, Seema Malkani, Dawei Zhang, Shankaranarayana Rao, Sumantra Chattarji, Raymond J Kelleher III, Eric R Kandel, Karen Duff, Alfredo Kirkwood, Jie Shen, Neurologic Diseases Brigham, Hospital Program, National Centre, Biological Sciences Bangalore, The Picower Center, Technology Cambridge, New York, De Strooper, FAD-linked PS, FAD-linked However, D Synapse (2004) Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration, 23-36. In Neuron.

Download PDF (718.9 KB)

Kamondanai Hemstapat, Maree T Smith, Gregory R Monteith (2004) Measurement of intracellular Ca 2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: potential application to biomolecular screening, 81 - 87. In Methods.

Download PDF (538.68 KB)

FRESH FROM T H E PIPELINE (2004) Memantine hydrochloride, 3-4. In Discovery 3 (February).

Download PDF (104.53 KB)

Randy L Buckner, Psychology One Brookings Drive Campus Box (2004) Memory and Executive Function Review in Aging and AD: Multiple Factors that Cause Decline and Reserve Factors that Compensate, 195-208. In Neuron.

Download PDF (447.02 KB)

Simon Melov (2004) Modeling mitochondrial function in aging neurons. In Trends in Neurosciences 27 (10).

Download PDF (323.64 KB)

Michelle M Aarts, Michael Tymianski (2004) Molecular Mechanisms Underlying Specificity of Excitotoxic Signaling in Neurons, 133-143. In Current Molecular Medicine.

Download PDF (211.19 KB)

Ella Bossy-Wetzel, Robert Schwarzenbacher (2004) Molecular pathways to neurodegeneration, 2-9. In NEURODEGENERATION.

Download PDF (1.06 MB)

(2004) N-Methyl-D-Aspartate (NMDA) receptor antagonists as potential therapeutic agents in neurodegenerative diseases, 50-51. 36 (1).

Download PDF (93.83 KB)

NEURODEGENERATIVE DISEASESOXIDATIVE STRESS (2004) Neurodegenerative diseases and oxidative stress. In Discovery 3 (March).

Download PDF (243 KB)

Akihiko Nunomura, Shigeru Chiba, Carol F Lippa, Patrick Cras, Rajesh N Kalaria, Atsushi Takeda, Kazuhiro Honda, Mark A Smith, George Perry (2004) Neuronal RNA oxidation is a prominent feature of familial Alzheimer’s disease, 108 - 113. In Neurobiology of Disease.

Download PDF (1.15 MB)

Frank M Longo, Stephen M Massa (2004) Neuroprotective Strategies in Alzheimer’s Disease, 117-127. In Neurotherapeutics 1 (January).

Download PDF (116.86 KB)

Sandra I Kim, Hans Voshol, Terri G Hastings, Michael Cascio, Marc J Glucksman (2004) Neuroproteomics: Expression Pro ling of the Brain’s Proteomes in Health and Disease*, 1317-1331. In Neurochemical Research 29 (6).

Download PDF (214.32 KB)

F Ashcroft, D Benos, F Bezanilla, K Chien, S Choe, D Clapham, D Dougherty, M Lazdunski, I Levitan, R Lewis, B Liss, S Lummis, C Miller, A North, J Peters, M Sanguinetti, T Smart, W St (2004) No title.. In Discovery 3 (March).

Download PDF (1.37 MB)

Laura Gasparini, Ennio Ongini, Gary Wenk (2004) Non-steroidal anti-in ammatory drugs (NSAIDs) in Alzheimer’s disease: old and new mechanisms of action, 521-536. In Journal of Neurochemistry.

Download PDF (217.64 KB)

So-Young Choi, Jung Jin Hwang, Jae-Young Koh (2004) NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture, 1-9. In Drugs.

Download PDF (402.5 KB)

Suk Jin Hong, Ted M Dawson, Valina L Dawson (2004) Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling, 1-6. In Trends in Pharmacological Sciences 25 (5).

Download PDF (1.17 MB)

Nature Publishing Group, S. (2004) Oxidative stress in neurodegeneration: cause or consequence?, 18-25. In NEURODEGENERATION.

Download PDF (591.51 KB)

Yanpeng Lin, Angele Desbois, Susan Jiang, Sheng T Hou (2004) P2 receptor antagonist PPADS confers neuroprotection against glutamate/NMDA toxicity, 22-25. In Neuroscience Letters.

Download PDF (143.28 KB)

Neurological Disorders, Pervasive Problem (2004) Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine, 18-20. In Drugs.

Download PDF (81.12 KB)

Mark P Mattson (2004) Pathways towards and away from Alzheimer’s disease, 631-639. In Nature.

Download PDF (4.65 MB)

Raphael Kopan (2004) Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration, 26-33. In NEURODEGENERATION.

Download PDF (1.47 MB)

Els Marjaux, Dieter Hartmann, Bart De Strooper, Neuronal Cell Biology, Gene Transfer Center, Human Genetics, U Z Gasthuisberg Herestraat, Leuven Belgium (2004) Presenilins in Memory, Alzheimer’s Disease, and Therapy, 189-192. In Neuron.

Download PDF (78.99 KB)

Nature Publishing Group (2004) Protein aggregation and neurodegenerative disease, 10-17. In Aging.

Download PDF (675.38 KB)

Allan Butterfield (2004) Proteomics: a new approach to investigate oxidative stress in Alzheimer’s disease brain, 1 - 7. In Brain.

Download PDF (215.43 KB)

YANN VERDIER, ARTA Z A R ANDI, BOTOND PENKE (2004) Received 9 February 2004 Accepted 11 February 2004, 229-248. In Journal of Peptide Science.

Download PDF (309.12 KB)

Lin Pei, Frank J S Lee, Anna Moszczynska, Brian Vukusic, Fang Liu (2004) Regulation of Dopamine D1 Receptor Function by Physical Interaction with the NMDA Receptors, 1149 -1158. 24 (5).

Download PDF (680.77 KB)

BRYAN R JARABEK, ROBERT P YASUDA, Barry B Wolfe (2004) Regulation of proteins affecting NMDA receptor- induced excitotoxicity in a Huntington's mouse model. In Brain 127 (3).

Download PDF (375.73 KB)

Pierluigi Nicotera, Gerry Melino (2004) Regulation of the apoptosis–necrosis switch, 2757-2765. In Oncogene.

Download PDF (280.91 KB)

Sermin Genc, Tolga F Koroglu, Kursad Genc (2004) RNA interference in neuroscience, 260 - 270. In Molecular Brain Research.

Download PDF (276.75 KB)

S E E Last Page (2004) Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity, 1021-1025. In Science 304 (May).

Download PDF (441.23 KB)

Section III, Cell Function (2004) Section III: Mitochondria, ␤ -Cell Function, and Type 2 Diabetes. In Diabetes 53 (February).

Download PDF (80.36 KB)

Matthew R Hynd, Heather L Scott, Peter R Dodd (2004) Selective loss of NMDA receptor NR1 subunit isoforms in Alzheimer’s disease, 240-247. In Journal of Neurochemistry.

Download PDF (170.34 KB)

S Diego (2004) SFN, 2004 (S. Diego, USA)..

Download PDF (46.31 KB)

Rodrigo A Fuentealba, Ginny Farias, Jessica Scheu, Miguel Bronfman, Paz Marzolo, Nibaldo C Inestrosa (2004) Signal transduction during amyloid-h-peptide neurotoxicity: role in Alzheimer disease, 275 - 289. In Brain Research Reviews.

Download PDF (536.32 KB)

Although RNAi (2004) Silencing the sceptics, 1-4. In Discovery 3 (December).

Download PDF (311.78 KB)

Michael W Salter, Lorraine V Kalia (2004) Src kinases: a hub for nmda receptor regulation. In Group 5 (April).

Download PDF (597.41 KB)

Olle Lindvall, Zaal Kokaia, Alberto Martinez-Serrano (2004) Stem cell therapy for human neurodegenerative disorders–how to make it work, 42-50. In Molecular Biology.

Download PDF (6.05 MB)

STRATEGIES F O R DISEASE MODIFICATIONALZHEIMER (2004) Strategies for disease modification in alzheimer’s disease. In Neuroscience 5 (September).

Download PDF (775.9 KB)

Nibaldo C Inestrosa, Carlos Morgan, Marcela Colombres, Marco Tulio Nun (2004) Structure and function of amyloid in Alzheimer’s disease ˜, 323-349. In Water.

Download PDF (776.92 KB)

Lonnie P Wollmuth, Alexander I Sobolevsky (2004) Structure and gating of the glutamate receptor ion channel. In Trends in Neurosciences 27 (6).

Download PDF (569.06 KB)

Koichi Suzuki, Shoji Hata, Yukiko Kawabata, Hiroyuki Sorimachi (2004) Structure, Activation, and Biology of Calpain. In Diabetes 53 (February).

Download PDF (455.6 KB)

ANTHONE W DUNAH, David G Standaert (2004) Subcellular segregation of distinct heteromeric NMDA glutamate receptors in the striatum, 935-943. In Journal of Neurochemistry.

Download PDF (195.83 KB)

Xiao-Bo Liu, Karl D Murray, Edward G Jones (2004) Switching of NMDA Receptor 2A and 2B Subunits at Thalamic and Cortical Synapses during Early Postnatal Development, 8885- 8895. In Journal of Neuroscience 24 (40).

Download PDF (740.47 KB)

Barbara Nawrot (2004) Targeting BACE with small inhibitory nucleic acids — a future for Alzheimer’s disease therapy? *., 431-444. In Small 51 (2).

Download PDF (998.79 KB)

Stefan Grimm (2004) The art and design of genetic screens: mammalian culture cells. In Genetics 5 (March).

Download PDF (350.19 KB)

Giancarlo Zatti, Roberta Ghidoni, Laura Barbiero, Giuliano Binetti, Tullio Pozzan, Cristina Fasolato, Paola Pizzo (2004) The presenilin 2 M239I mutation associated with familial Alzheimer’s disease reduces Ca 2+ release from intracellular stores, 269 - 278. In Neurobiology of Disease.

Download PDF (495.98 KB)

Giancarlo Zatti, Roberta Ghidoni, Laura Barbiero, Giuliano Binetti, Tullio Pozzan, Cristina Fasolato, Paola Pizzo (2004) The presenilin 2 M239I mutation associated with familial Alzheimer’s disease reduces Ca 2+ release from intracellular stores, 269 - 278. In Neurobiology of Disease.

Download PDF (495.98 KB)

N E U OBIOLOGI, EXPE IMENT LIS, Hyoung-gon Lee, Xiongwei Zhu, Kate Webber, Gemma Casadesus, Michael Marlatt, Arun K Raina, George Perry, Mark A Smith (2004) The role of metabotropic glutamate receptors in Alzheimer’s disease, 89-98. In Acta Neurobiol Exp.

Download PDF (92.48 KB)

Mouldy Sioud (2004) Therapeutic siRNAs, 22-28. In Trends in Pharmacological Sciences 25 (1).

Download PDF (348.52 KB)

Amyloid Peptide Channels (2004) Topical Review, 1-10. In J Membrane Biol.

Download PDF (126.37 KB)

Laura Canevari, Andrey Abramov, Michael R Duchen (2004) Toxicity of Amyloid ␤ Peptide: Tales of Calcium, Mitochondria, and Oxidative Stress*, 637-650. In Neurochemical Research 29 (3).

Download PDF (295.67 KB)

Laura Canevari, Andrey Abramov, Michael R Duchen (2004) Toxicity of Amyloid ␤ Peptide: Tales of Calcium, Mitochondria, and Oxidative Stress*, 637-650. In Neurochemical Research 29 (3).

Download PDF (294.86 KB)

Karl Zilles, Nicola Palomero-Gallagher, AXEL SCHLEICHER (2004) Transmitter receptors and functional anatomy of the cerebral cortex, 417-432. In J Anat.

Download PDF (503.13 KB)

Neurology Massachusetts General Hospital Charlestown, Inc La Jolla, George Glenner (2004) Which cleave APP to liberate A␤. The rationale for this approach is that a reduction in A␤, 605-608. In Neuron.

Download PDF (98.08 KB)

Craig S Atwood, Mark E Obrenovich, Tianbing Liu, Hsien Chan, George Perry, Mark A Smith, Ralph N Martins (2003) A myloid-b: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-b, 1-16. In Psychiatry and Clinical Neurosciences.

Download PDF (466.27 KB)

Jianmin Zhang, Xiaobing Wu, Chuan Qin, Jin Qi, Huiyuan Zhang, Qingli Kong, Dongqing Chen, Denian Ba, Wei He (2003) A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and ␤ -amyloid plaques in a mouse model of Alzheimer’s disease, 365-379. In Neurobiology of Disease.

Download PDF (619.63 KB)

Debby Van Dam, Matthias Staufenbiel, Chris Van Ginneken, Frans Van Meir, De Deyn (2003) Age-dependent cognitive decline in the APP23 model precedes amyloid deposition, 388-396. In European Journal of Neuroscience 17 (August 2002).

Download PDF (316.61 KB)

Dennis J Selkoe (2003) Aging, Amyloid, and Alzheimer’s Disease: A Perspective in Honor of Carl Cotman*, 1705-1713. In Neurochemical Research 28 (11).

Download PDF (78.33 KB)

Todd E Golde (2003) Alzheimer disease therapy: Can the amyloid cascade be halted?, 11-18. In Journal of Clinical Investigation 111 (1).

Download PDF (547 KB)

Robert L Nussbaum, Christopher E Ellis (2003) Alzheimer’s Disease and Parkinson’s Disease. In Society.

Download PDF (278.8 KB)

Kun Zou, Daesung Kim, Atsuko Kakio, Kyunghee Byun, Jian-sheng Gong, Jaewoo Kim, Myeungju Kim, Naoya Sawamura, Sei-ichi Nishimoto, Katsumi Matsuzaki, Bonghee Lee, Katsuhiko Yanagisawa, Makoto Michikawa (2003) Amyloid b-protein (Ab)1–40 protects neurons from damage induced by Ab1–42 in culture and in rat brain, 609-619. In Journal of Neurochemistry.

Download PDF (365.89 KB)

Salvatore Oddo, Antonella Caccamo, Masashi Kitazawa, Bertrand P Tseng, Frank M LaFerla (2003) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease, 1063-1070. In Neurobiology of Aging.

Download PDF (560.89 KB)

Pierre A Mattar, Kevin D Holmes, Gregory A Dekaban (2003) An Antisense Construct Reduces, 782-793. In Journal of Neuroscience Research.

Download PDF (601.92 KB)

Neurodegenerative Diseases (2003) Apoptosis and Caspases in Neurodegenerative Diseases, 1365-1375. In Society.

Download PDF (335.89 KB)

Alfons Lawen (2003) Apoptosis—an introduction, 888-896. In Molecular Biology.

Download PDF (343.71 KB)

Flavio Kamenetz, Taisuke Tomita, Helen Hsieh, Guy Seabrook, David Borchelt, Takeshi Iwatsubo, Sangram Sisodia, Roberto Malinow, Cold Spring Harbor Laboratory Cold Spring Harbor, New York, Stony Brook Stonybrook, Tokyo Tokyo Japan, Merck Research Laboratories Merck, Incorporated WP, Sumneytown Pike West Point, Medicine Baltimore, Chicago Chicago (2003) APP Processing and Synaptic Function, 925-937. In Neuron.

Download PDF (612 KB)

Neville Marks, Martin J Berg (2003) APP Processing Enzymes (Secretases) as Therapeutic Targets: Insights from the Use of Transgenics (Tgs) and Transfected Cells*, 1049-1062. In Neurochemical Research 28 (7).

Download PDF (299.96 KB)

The Journal, Cell Biology (2003) APP processing is regulated by cytoplasmic phosphorylation, 83-95. In The Journal of Cell Biology.

Download PDF (720.31 KB)

Stefanie Ortinau, Bodo Laube, Herbert Zimmermann (2003) ATP Inhibits NMDA Receptors after Heterologous Expression and in Cultured Hippocampal Neurons and Attenuates NMDA-Mediated Neurotoxicity, 4996 -5003. In Control 23 (12).

Download PDF (346 KB)

Ellen S Mitchell, Abigail Snyder-Keller (2003) C-fos and cleaved caspase-3 expression after perinatal exposure to ethanol, cocaine, or the combination of both drugs, 107 - 117. In Developmental Brain Research.

Download PDF (659.85 KB)

Experimental Neurology Copyright, Neuropathologists Vol (2003) Calpain Facilitates the Neuron Death Induced by 3-Nitropropionic Acid and Contributes to the Necrotic Morphology, 633-643. In Experimental Neurology 62 (6).

Download PDF (818.31 KB)

Nicolas Bizat, Jean-Michel Hermel, Carine Jacquard, Christophe Cre, Carole Escartin, Philippe Hantraye, Stan Krajewski, Emmanuel Brouillet (2003) Calpain Is a Major Cell Death Effector in Selective Striatal Degeneration Induced, 5020 -5030. In Journal of Neuroscience 23 (12).

Download PDF (759.22 KB)

Jochen Herms, Ilka Schneider, Ilse Dewachter, Nathalie Caluwaerts, Hans Kretzschmar, Fred Van Leuven (2003) Capacitive Calcium Entry Is Directly Attenuated by Mutant Presenilin-1, Independent of the Expression of the Amyloid Precursor Protein*, 2484 -2489. In Molecular Biology 278 (4).

Download PDF (293 KB)

Jian Wang, ShuHong Liu, YangPing Fu, YouMing Lu (2003) Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors, 1039-1047. In October 6 (10).

Download PDF (1.61 MB)

Ming-Sum Lee, Li-Huei Tsai (2003) Cdk5: One of the links between senile plaques and neuro brillary tangles?, 127-137. In In vitro.

Download PDF (66.69 KB)

Minh Dang Nguyen, Mathieu Boudreau, Jasna Kriz, David R Kaplan, Jean-Pierre Julien (2003) Cell Cycle Regulators in the Neuronal Death Pathway of Amyotrophic Lateral Sclerosis Caused by Mutant Superoxide Dismutase 1, 2131-2140. In Amyotrophic Lateral Sclerosis 23 (6).

Download PDF (816.08 KB)

Robert W Neumar, Anne Xu, Hemal Gada, RODNEY P GUTTMANN, Robert Siman (2003) Cross-talk between Calpain and Caspase Proteolytic Systems During Neuronal Apoptosis*, 14162-14167. In Molecular Biology 278 (16).

Download PDF (328.37 KB)

Bo Li, Yo Otsu, Timothy H Murphy, Lynn A Raymond (2003) Developmental Decrease in NMDA Receptor Desensitization Associated with Shift to Synapse and Interaction with Postsynaptic Density-95, 11244 -11254. 23 (35).

Download PDF (808.81 KB)

Junying Yuan, Marta Lipinski, Longwood Avenue Boston, Wyllie Kerr (2003) Diversity in the Mechanisms of Neuronal Cell Death, 401-413. In October.

Download PDF (260.88 KB)

Junying Yuan, Marta Lipinski, Longwood Avenue Boston, Wyllie Kerr (2003) Diversity in the Mechanisms of Neuronal Cell Death, 401-413. In October.

Download PDF (262.38 KB)

MARY L MICHAELIS (2003) Drugs Targeting Alzheimer’s Disease: Some Things Old and Some Things New, 897-904. In Pharmacology 304 (3).

Download PDF (340.08 KB)

N E U OBIOLOGI, EXPE IMENT LIS, Maria Brzyska, Danek Elbaum (2003) Dysregulation of calcium in Alzheimer’s disease, 171-183. In Acta Neurobiol Exp.

Download PDF (192.96 KB)

Thetford Smothers, John J Woodward (2003) E ffect of the NR3 subunit on ethanol inhibition of recombinant NMDA receptors, 117-121. In Brain Research.

Download PDF (302.94 KB)

Neuroscience Review Series (2003) Endoplasmic reticulum Ca 2+ homeostasis and neuronal death, 351-361. In Journal of Cellular and Molecular Medicine 7 (4).

Download PDF (661.29 KB)

Silvia Gines, Elena Ivanova, Ihn-Sik Seong, Carlos A Saura, Marcy E MacDonald (2003) Enhanced Akt Signaling Is an Early Pro-survival Response That Reflects, 50514 -50522. In Molecular Biology 278 (50).

Download PDF (459.56 KB)

Sascha Weggen, Jason L Eriksen, Sarah A Sagi, Claus U Pietrzik, Victor Ozols, Abdul Fauq, Edward H Koo (2003) Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid ␤ 42 Production by Direct Modulation of ␥ -Secretase Activity*, 31831-31837. In Molecular Biology 278 (34).

Download PDF (163.5 KB)

Amanda J Law, Cynthia Shannon Weickert, Maree J Webster, Mary M Herman, Joel E Kleinman, Paul J Harrison (2003) Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation, 1197-1205. In European Journal of Neuroscience.

Download PDF (348.74 KB)

Cheng Song, Yuntian Zhang, Chris G Parsons, Ya Fang Liu (2003) Expression of Polyglutamine-expanded Huntingtin Induces Tyrosine Phosphorylation of, 33364 -33369. In Molecular Biology 278 (35).

Download PDF (295.44 KB)

Marianne Leirdal, Mouldy Sioud (2003) Gene Silencing by Systemic Delivery of Synthetic siRNAs in Adult Mice, 761-766. In J Mol Biol 2836 (03).

Download PDF (756.58 KB)

ShuHong Liu, Jian Wang, DongYa Zhu, YangPing Fu, Ken Lukowiak, YouMing Lu (2003) Generation of Functional Inhibitory Neurons in the Adult Rat Hippocampus, 732-736. In Journal of Neuroscience 23 (3).

Download PDF (519.09 KB)

Hiromi Hiruma, Takashi Katakura, Sanae Takahashi, Takafumi Ichikawa, Tadashi Kawakami (2003) Glutamate and Amyloid ␤ -Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different Mechanisms, 8967- 8977. In Solutions 23 (26).

Download PDF (710.03 KB)

Yi Nong, Yue-Qiao Huang, William Ju, Lorraine V Kalia, Gholamreza Ahmadian, Yu Tian Wang, Michael W Salter (2003) Glycine binding primes NMDA receptor internalization. In Nature 422 (March).

Download PDF (522.63 KB)

Blaine Stine, Karie N Dahlgren, Grant A Krafft, Mary Jo LaDu (2003) In Vitro, 11612-11622. In Molecular Biology 278 (13).

Download PDF (1.06 MB)

IMPLICATION OF, CALPAIN-MEDIATED CLEAVAGE O F ACTIVE CASPASE- (2003) In Vivo, 43245-43253. In Molecular Biology 278 (44).

Download PDF (518.28 KB)

Neurochemistry International, Drug Safety Research, Gedeon Richter Ltd, Hungary Received (2003) Inducible expression and pharmacology of recombinant NMDA receptors, composed of rat NR1a/NR2B subunits, 19-29. In Neurochemistry International.

Download PDF (313.64 KB)

Gail K Seabold, Alain Burette, Indra A Lim, Richard J Weinberg, Johannes W Hell (2003) Interaction of the Tyrosine Kinase Pyk2 with the, 15040 -15048. In Molecular Biology 278 (17).

Download PDF (674 KB)

Zhihua Qiu, Donna L Gruol (2003) Interleukin-6, h-amyloid peptide and NMDA interactions in rat cortical neurons, 51 - 57. In J Biol Chem.

Download PDF (326.01 KB)

Intracellular Ca, Human Disease, The Hunt Begins (2003) Intracellular Ca 2؉ Signaling and Human Disease: The Hunt Begins with Huntington’s, 195-197. In Neuron.

Download PDF (122.69 KB)

Georg Ko, Vidar Jensen, Helmut J Koester, Andre L A Mihaljevic, Jo K Utvik, Ane Kvello, Ole P Ottersen, Peter H Seeburg, Rolf Sprengel (2003) Intracellular Domains of NMDA Receptor Subtypes Are Determinants for Long-Term Potentiation Induction, 10791-10799. In Journal of Neuroscience 23 (34).

Download PDF (322.62 KB)

Paula Agostinho, Catarina Resende Oliveira (2003) Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides. In European Journal of Neuroscience.

Download PDF (250.53 KB)

Kiyoshi Morimoto, Tomiichiro Oda (2003) Kainate exacerbates b-amyloid toxicity in rat hippocampus, 242-244. In Neuroscience Letters.

Download PDF (107.37 KB)

Derek M Dykxhoorn, Carl D Novina, Phillip A Sharp (2003) Killing the messenger: short rnas that silence gene expression. In Cell 4 (June).

Download PDF (585.59 KB)

Wulf Paschen (2003) Mechanisms of neuronal cell death: diverse roles of calcium in the various subcellular compartments, 305-310. In In Vivo.

Download PDF (70.65 KB)

This Provisional PDF, Microbial Cell Factories, Subhra Chakrabarti, Amiya R Nayak (2003) Microbial Cell Factories. In Microbial Cell Factories.

Download PDF (292 KB)

Physiol Biochem February (2003) Mitochondrial control of neuron death and its role in neurodegenerative disorders Joaquin Jordan 1,3 and Jochen H M Prehn 2, 1-22. In Neurodegeneration.

Download PDF (515.06 KB)

Cristina Rego, Catarina R Oliveira (2003) Mitochondrial Dysfunction and Reactive Oxygen Species in Excitotoxicity and Apoptosis: Implications for the Pathogenesis of Neurodegenerative Diseases*, 1563-1574. In Neurochemical Research 28 (10).

Download PDF (315.64 KB)

Anne Eckert, Uta Keil, Celio A Marques, Astrid Bonert, Walter E Mu, Claudia Frey, Katrin Schu (2003) Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease, 1627-1634. In J Biol Chem.

Download PDF (344.98 KB)

Mark Arundine, Michael Tymianski (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity, 325-337. In Cell Calcium.

Download PDF (153.88 KB)

Clarke R Raymond, David R Ireland, Wickliffe C Abraham (2003) N MDA receptor regulation by amyloid-b does not account for its inhibition of LTP in rat hippocampus, 263-272. In Brain Research.

Download PDF (605.09 KB)

Oxidative Stress, T H E J N K PATHWAY (2003) Neurotoxic Mechanisms Caused by the Alzheimer’s Disease-linked Swedish Amyloid Precursor Protein Mutation, 28294 -28302. In Molecular Biology 278 (30).

Download PDF (395.45 KB)

Mark P Mattson, Sic L Chan (2003) News and views, 1041-1043. In Group 5 (12).

Download PDF (201.55 KB)

David Baltimore (2003) NF-κB functions in synaptic signaling and behavior, 1072-1078. In October 6 (10).

Download PDF (812.16 KB)

Gerald A Rameau, Ling-Yu Chiu, Edward B Ziff (2003) NMDA receptor regulation of nNOS phosphorylation and induction of neuron death, 1123-1133. In Neurobiology of Aging.

Download PDF (413.54 KB)

Kirsten S Dickson, Peter C Kind, NMDA Receptors, Eye-Specific Segregation How, The LGN (2003) NMDA Receptors: Neural Map Designers and Refiners?, 920-922. In Current Biology.

Download PDF (71.27 KB)

Kirsten S Dickson, Peter C Kind, NMDA Receptors, Eye-Specific Segregation How, The LGN (2003) NMDA Receptors: Neural Map Designers and Refiners?, 920-922. In Current Biology.

Download PDF (71.95 KB)

Surojit Paul, Angus C Nairn, Ping Wang, Paul J Lombroso (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. In New York 6 (1).

Download PDF (965.36 KB)

RICHARD M KOSTRZEWAa, JUAN SEGURA-AGUILARb (2003) Novel Mechanisms and Approaches in the Study of Neurodegeneration and Neuroprotection. A Review., 375-384. In Neurotoxicity Research 5 (6).

Download PDF (435.19 KB)

Stephen G Brickley, Charu Misra, Selina Mok, Masayoshi Mishina, Stuart G Cull-Candy (2003) NR2B and NR2D Subunits Coassemble in Cerebellar Golgi Cells to Form a Distinct NMDA Receptor Subtype Restricted to Extrasynaptic Sites, 4958 - 4966. In Journal of Neuroscience 23 (12).

Download PDF (222.55 KB)

Peter Vanhoutte, Hilmar Bading (2003) Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation, 366-371. In Current Opinion in Neurobiology.

Download PDF (120.94 KB)

Yan Zhang, Yanguo Hong, Younes Bounhar, Megan Blacker, Xavier Roucou, Omar Tounekti, Emily Vereker, William J Bowers, Howard J Federoff, Cynthia G Goodyer (2003) P75 Neurotrophin Receptor Protects Primary Cultures of Human Neurons against Extracellular Amyloid ␤ Peptide Cytotoxicity, 7385-7394. 23 (19).

Download PDF (621.29 KB)

Sanjay S Kumar, John R Huguenard (2003) Pathway-Specific Differences in Subunit Composition of Synaptic NMDA Receptors on Pyramidal Neurons in Neocortex, 10074 -10083. In Journal of Neuroscience 23 (31).

Download PDF (320.25 KB)

Noriko Okuyama, Norio Takagi, Takayuki Kawai, Keiko Miyake-Takagi, Satoshi Takeo (2003) Phosphorylation of extracellular-regulating kinase in NMDA receptor antagonist-induced newly generated neurons in the adult rat dentate gyrus, 1-9. In Journal of Neurochemistry.

Download PDF (439.67 KB)

Dongming Cai, Jae Yoon Leem, Jeffrey P Greenfield, Pei Wang, Benny S Kim, Runsheng Wang, Kryslaine O Lopes, Seong-Hun Kim, Hui Zheng, Paul Greengard, Sangram S Sisodia, Gopal Thinakaran, Huaxi Xu (2003) Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of ␤ -Amyloid Precursor Protein*, 3446 -3454. In Molecular Biology 278 (5).

Download PDF (617.76 KB)

(2003) Preventing and treating Alzheimer’s disease: strategies and prospects, 565-569. In Neurotherapeutics.

Download PDF (79.35 KB)

F P MONNET, M P MORIN, J LEGER, L COMBETTES (2003) Protein Kinase C-Dependent Potentiation of Intracellular Calcium Influx by ␴ 1 Receptor Agonists in Rat Hippocampal Neurons, 705-712. In Pharmacology 307 (2).

Download PDF (284.03 KB)

Feldmann Jr, Wolfgang Kuschinsky (2003) Proteome Science, 1-7. In Critical Care Medicine.

Download PDF (501 KB)

Feldmann Jr, Wolfgang Kuschinsky (2003) Proteome Science, 1-7. In Critical Care Medicine.

Download PDF (534.58 KB)

Allan Butter, Debra Boyd-Kimball, Alessandra Castegna (2003) Proteomics in Alzheimer’s disease: insights into potential mechanisms of neurodegeneration, 1313-1327. In Journal of Neurochemistry.

Download PDF (483.23 KB)

Allan Butter, Debra Boyd-Kimball, Alessandra Castegna (2003) Proteomics in Alzheimer’s disease: insights into potential mechanisms of neurodegeneration, 1313-1327. In Journal of Neurochemistry.

Download PDF (483.23 KB)

Sten Orrenius, Boris Zhivotovsky, Pierluigi Nicotera (2003) Regulation of cell death: the calcium–apoptosis link, 552-565. In Cell 4 (July).

Download PDF (4.68 MB)

Research Article (2003) Research Article 525. In Proteins.

Download PDF (813.82 KB)

OLLIVIER MILHAVET, DEVIN S GARY, Mark P Mattson (2003) RNA Interference in Biology and Medicine, 629-648. In Pharmacol Rev 55 (4).

Download PDF (328.94 KB)

REVIEW Christoph Arenz, Ute Schepers (2003) RNA interference: from an ancient mechanism to a state of the art therapeutic application?, 345-359. In Naturwissenschaften.

Download PDF (380.21 KB)

Lijun Li, Mannie Fan, Carolyn D Icton, Nansheng Chen, Blair R Leavitt, Michael R Hayden, Tim H Murphy, Lynn A Raymond (2003) Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease, 1113-1121. In Animals.

Download PDF (166.92 KB)

Paul R Turner, Warren P Tate, Wickliffe C Abraham (2003) Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory, 1-32. In Progress in Neurobiology.

Download PDF (976.92 KB)

KELLY L SIMPKINS, RODNEY P GUTTMANN, YINA DONG, Zhaoming Chen, Set Sokol, Robert W Neumar, David R Lynch (2003) Selective Activation Induced Cleavage of the NR2B Subunit by Calpain, 11322-11331. In Journal of Neuroscience 23 (36).

Download PDF (428.09 KB)

Wataru Kakegawa, Keisuke Tsuzuki, Masae Iino, Seiji Ozawa (2003) SHORT COMMUNICATION Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells, 887-891. In European Journal of Neuroscience 17 (October 2002).

Download PDF (253.32 KB)

Eric G Moss (2003) Silencing unhealthy alleles naturally, 185-187. In Trends in biotechnology 21 (5).

Download PDF (87.06 KB)

Keiko Matsuda, Matt Fletcher, Yoshinori Kamiya, Michisuke Yuzaki (2003) Specific Assembly with the NMDA Receptor 3B Subunit Controls Surface Expression and Calcium Permeability of NMDA Receptors, 10064 -10073. In Journal of Neuroscience 23 (31).

Download PDF (432.2 KB)

Popi Syntichaki, Nektarios Tavernarakis (2003) The biochemistry of neuronal necrosis: rogue biology?, 672-684. In Group 4 (August).

Download PDF (1.13 MB)

Cristine Alves, Mark P Mattson, Karine Ancolio (2003) The C-terminal Fragment of Presenilin 2 Triggers p53-mediated Staurosporine-induced Apoptosis, a Function Independent of the Presenilinase-derived N-terminal Counterpart*, 12064 -12069. In Molecular Biology 278 (14).

Download PDF (260.99 KB)

Ralph A Nixon (2003) The calpains in aging and aging-related diseases, 407-418. In Ageing Research Reviews.

Download PDF (105.58 KB)

Therapeutic Implications (2003) The Glutamatergic System and Alzheimer’s Disease, 641-652. In CNS Drugs 17 (9).

Download PDF (243.91 KB)

Jennifer M Loftis, Aaron Janowsky (2003) The N-methyl-, 55 - 85. In Pharmacology & Therapeutics.

Download PDF (837.85 KB)

Grigory Krapivinsky, Luba Krapivinsky, Yunona Manasian, Anton Ivanov, Roman Tyzio, Christophe Pellegrino, Yehezkel Ben-Ari, David E Clapham, Igor Medina, Enders Building, Longwood Avenue Boston, INSERM Unite, Marseille France, The NMDAR-initiated ERK, K SynGAP, Ras-specific GDP, NMDAR-dependent ERK, Results Agonist (2003) The NMDA Receptor Is Coupled to the ERK Pathway by a Direct Interaction between NR2B and RasGRF1, 775-784. In Neuron.

Download PDF (576.25 KB)

Brief Communication, Leigh D Plant, John P Boyle, Ian F Smith, Chris Peers, Hugh A Pearson (2003) The Production of Amyloid ␤ Peptide Is a Critical Requirement for the Viability of Central Neurons, 5531-5535. In Journal of Neuroscience 23 (13).

Download PDF (159.19 KB)

Murali Doraiswamy (2003) The Role of the. In Current Neurology and Neuroscience Reports.

Download PDF (363.73 KB)

Giles E Hardingham, Hilmar Bading (2003) The Yin and Yang of NMDA receptor signalling, 81-89. In Trends in Neurosciences 26 (2).

Download PDF (281.74 KB)

Gregory P Gasic, Pierluigi Nicotera (2003) To die or to sleep, perhaps to dream, 221-227. In J Neurochem.

Download PDF (122.2 KB)

Jon Popke, When MK- (2003) TOXICOLOGICAL HIGHLIGHT From Anticholinesterase Toxicity to Alzheimer’s Disease: Important Interactions of Cholinergic and NMDA Receptor Systems, 185-187. In TOXICOLOGICAL SCIENCES.

Download PDF (54 KB)

Elio Scarpini, Philip Scheltens, Howard Feldman (2003) Treatment of Alzheimer’s disease: current status and new perspectives, 539-547. In The Lancet 2 (September).

Download PDF (191.07 KB)

Salvatore Oddo, Antonella Caccamo, Jason D Shepherd, Paul Murphy, Todd E Golde, Rakez Kayed, Raju Metherate, Mark P Mattson, Yama Akbari, Frank M LaFerla, Molecular Biology, Irvine Irvine, Pharmacology Mayo Clinic Jacksonville Jacksonville, Aging Baltimore (2003) Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles: Intracellular A␤ and Synaptic Dysfunction, 409-421. In Neuron.

Download PDF (681.17 KB)

Toshio Narahashi, William Marszalec, Shigeki Moriguchi, Jay Z Yeh, Xilong Zhao (2003) Unique mechanism of action of Alzheimer’s drugs on brain nicotinic acetylcholine receptors and NMDA receptors, 281 - 291. In Life Sciences.

Download PDF (203.73 KB)

DELETION ANALYSISROLESUBCELLULAR DISTRIBUTION (2002) -aspartate Receptor Splice Variant NR1– 4 C-terminal Domain, 1457-1468. In Molecular Biology 277 (2).

Download PDF (834.38 KB)

Yves P Auberson, Hans Allgeier, Serge Bischo, Kurt Lingenhoehl, Robert Moretti, Markus Schmutz (2002) 5-Phosphonomethylquinoxalinediones as Competitive NMDA Receptor Antagonists with a Preference for the Human 1A/2A, Rather than 1A/2B Receptor Composition, 1099-1102. In Bioorganic & Medicinal Chemistry Letters.

Download PDF (134.96 KB)

W Baumeister, J Walz, F Zuhl, E Seemuller, M H Glickman, D M Rubin, V A Fried, D Finley, F Confalonieri, M Duguet, J C Swaf, J Bromberg, S A Johnston, K Melcher, S Johnston, C Chang, A Ferdous, F Gonzalez, L Sun, T Kodadek, D Rubin, K Ferrell, C R M Wilkinson, W Dubiel, C Gordon, G Orphanides, H Wu, W S Lane, M Hampsey, D Reinberg, P C Dedon, J A Soults, C D Allis, M A Gorovsky, J E Hopper, D Lohr, P Venkov, J Zlatanova, Albert Johnston, Saeki, A Toh, H Yokosawa, C Schauber, N The (2002) 92, 367 (1998). 2., 550-553. In Science 296 (April).

Download PDF (276.26 KB)

Ya-li Zheng, Bing-Sheng Li, Niranjana D Amin, Wayne Albers, Harish C Pant, This Cdk (2002) A peptide derived from cyclin-dependent kinase activator (p35) speci cally inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells, 4427-4434. In Eur J Biochem.

Download PDF (343.93 KB)

Ralf D Steinmetz, Eugenio Fava, Pierluigi Nicotera, Dieter Steinhilber (2002) A simple cell line based in vitro test system for, 99 - 110. In Journal of Neuroscience Methods.

Download PDF (633.4 KB)

Dennis J Selkoe (2002) Alzheimer’s Disease Is a Synaptic Failure, 789-791. In October 298 (October).

Download PDF (166.33 KB)

Allan Butterfield (2002) Amyloid b-peptide (1– 42)-induced Oxidative Stress and Neurotoxicity: Implications for Neurodegeneration in Alzheimer’s Disease Brain. A Review*, 1307-1313. In Free Radical Research 36 (June).

Download PDF (138 KB)

Corinne Mbebi, Violaine Se, Luc Mercken, Laurent Pradier, Ulrike Mu, Jean-Philippe Loeffler (2002) Amyloid Precursor Protein Family-induced Neuronal Death Is Mediated by Impairment of the Neuroprotective Calcium/Calmodulin Protein Kinase IV-dependent Signaling Pathway*, 20979 -20990. In Molecular Biology 277 (23).

Download PDF (645.13 KB)

YOO-HUN SUHFREDERIC CHECLER (2002) Amyloid Precursor Protein, Presenilins, and ␣ -Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer’s Disease, 469-525. In Pharmacol Rev 54 (3).

Download PDF (737.25 KB)

Manh Hung Tran, Kiyofumi Yamada, Toshitaka Nabeshima (2002) Amyloid ␤ -peptide induces cholinergic dysfunction and cognitive de cits: a minireview, 1271-1283. In Hospital Pharmacy.

Download PDF (264.28 KB)

Ottavio V Vitolo, Antonino Sant, Vincenzo Costanzo, Fortunato Battaglia, Ottavio Arancio, Michael Shelanski (2002) Amyloid ␤ -peptide inhibition of the PKA͞CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling, 13217-13221. In October 99 (20).

Download PDF (263.1 KB)

Sean P Cregan, Andre Fortin, Jason G MacLaurin, Steven M Callaghan, Francesco Cecconi, Seong-Woon Yu, Ted M Dawson, Valina L Dawson, David S Park, Guido Kroemer, Ruth S Slack (2002) Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death, 507-517. In The Journal of Cell Biology 158 (3).

Download PDF (343.89 KB)

RANA A AL-HALLAQ, BRYAN R JARABEK, ZHANYAN FU, STEFANO VICINI, Barry B Wolfe, ROBERT P YASUDA (2002) Association of NR3A with the, 1119-1127. In Mol Pharmacol 62 (5).

Download PDF (295.98 KB)

Eric Devroe (2002) BMC Biotechnology, 1-5. In BMC Biotechnology.

Download PDF (233.88 KB)

Frank M LaFerla (2002) Calcium dyshomeostasis and intracellular signalling in alzheimer’s disease, 862-872. In Group 3 (November).

Download PDF (854 KB)

Carol M Troy, Guy S Salvesen, PROGRAMMED CELL DEATHAPOPTOSIS (2002) Caspases On The Brain, 145-150. In Trends Biochem Sci.

Download PDF (132 KB)

Patricia Mericko, Angela Helmirch, LuPeng Chen, Kenichi Kusamoto, Araz Toumadje, Christine Chapline, Denry Sato (2002) Cell Culture: Basic Procedures. In Most.

Download PDF (93.02 KB)

YASNORY F SASAKI, THOMAS ROTHE, LOUIS S PREMKUMAR, SAUMYA DAS, JIANKUN CUI, MARIA V TALANTOVA, HON-KIT WONG, Xiandi Gong, SHING F A I CHAN, DONGXIAN ZHANG, NOBUKI NAKANISHI, Nikolaus J Sucher, Stuart A Lipton, La Jolla, Hong Kong, Special Administrative Region, N R Interestingly (2002) Characterization and Comparison of the NR3A Subunit of the NMDA Receptor in Recombinant Systems and Primary Cortical Neurons, 2052-2063.

Download PDF (332.46 KB)

YASNORY F SASAKI, THOMAS ROTHE, LOUIS S PREMKUMAR, SAUMYA DAS, JIANKUN CUI, MARIA V TALANTOVA, HON-KIT WONG, Xiandi Gong, SHING F A I CHAN, DONGXIAN ZHANG, NOBUKI NAKANISHI, Nikolaus J Sucher, Stuart A Lipton, La Jolla, Hong Kong, Special Administrative Region, N R Interestingly (2002) Characterization and Comparison of the NR3A Subunit of the NMDA Receptor in Recombinant Systems and Primary Cortical Neurons, 2052-2063.

Download PDF (333 KB)

B L Schwab, D W Nicholson (2002) Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis, 818-831. In Cell Death And Differentiation.

Download PDF (692.52 KB)

MATERIALSMETHODS, HuH- Br, Health Science Research Resource Bank, Tissue Transformation Technologies, Endothelial Cell Growth Supplement, Culture Medium, Clonetics Co, AMINE PLUS (2002) Comparison of the Ef ciency and Safety of Non-viral Vector-Mediated Gene Transfer into a Wide Range of Human Cells. In Society 25 (July).

Download PDF (121.28 KB)

MARIA KOUZNETSOVA, BROOKE KELLEY, MAOXING SHEN, STANLEY A THAYER (2002) Desensitization of Cannabinoid-Mediated Presynaptic Inhibition of Neurotransmission Between Rat Hippocampal Neurons in Culture, 477-485. In Mol Pharmacol 61 (3).

Download PDF (274.18 KB)

Sabine Golde, Siddharthan Chandran, Guy C Brown, Alastair Compston (2002) Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression, 269-282.

Download PDF (581.52 KB)

Hidenori Taru, Yutaka Kirino, Toshiharu Suzuki (2002) Differential Roles of JIP Scaffold Proteins in the Modulation of Amyloid Precursor Protein Metabolism*, 27567-27574. In Molecular Biology 277 (30).

Download PDF (321.11 KB)

Laura Gasparini, William J Netzer, Paul Greengard, Huaxi Xu (2002) Does insulin dysfunction play a role in Alzheimer’s disease?, 288-293. In Trends in Pharmacological Sciences 23 (6).

Download PDF (276 KB)

Frank J S Lee, Sheng Xue, Lin Pei, Yushan Wang, Brian Vukusic, Nadege Che Yu Tian Wang, Hyman B Niznik, Xian-min Yu, Fang Liu, Neuroscience Centre, Mental Health Clarke Division, Toronto Toronto, Brain Research Center, Medicine Vancouver General Hospital, British Columbia Vancouver, British Columbia, P T P Src, NMDA Receptors Form, Carboxyl Tails To (2002) Dual Regulation of NMDA Receptor Functions by Direct Protein-Protein Interactions with the Dopamine D1 Receptor, 219-230. In October.

Download PDF (525.55 KB)

Stuart A Lipton, Ella Bossy-Wetzel Center, Guido Kroemer (2002) Dueling Activities of AIF in Cell Death versus Survival: DNA Binding and Redox Activity, 147-150. In October.

Download PDF (168.33 KB)

David R Lynch, RODNEY P GUTTMANN (2002) Excitotoxicity: Perspectives Based on, 717-723. In Pharmacology 300 (3).

Download PDF (113 KB)

Marina Pizzi, Flora Boroni, Andrea Bianchetti, Costantinos Moraitis, Ilenia Sarnico, Marina Benarese, Francesca Gof, Alessandra Valerio, PierFranco Spano (2002) Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line, 2342-2350. In European Journal of Neuroscience.

Download PDF (327.47 KB)

Download PDF (1015.94 KB)

G E WULF DRO, Introduction A From, Major Types, Free Radicals, Their Derivatives, Living Organisms A Reactive, Oxidative Stress Response, Redox Signaling A Maintenance, Nitric Oxide, Reactive Oxygen Species, Regulatory Mediators, Physiological Responses A Regulated, N O C ROS, Redox-Sensitive Targets, Signaling Cascades A Role, R O S E Oxidative, H Activation, I Activation, J Importance, K Differential, L Key, Stress Conditions, Pathophysiological Implications, Redox Regulation A Mediators (2002) Free Radicals in the Physiological Control of Cell Function ¨, 47-95. In Physiol Rev.

Download PDF (666.37 KB)

ZHI-XING YAOVASSILIOS PAPADOPOULOS, SPECIFIC AIMS, Principal Findings (2002) Function of, 1677-1679. In The FASEB Journal.

Download PDF (235.08 KB)

H Luo, Fu, G Losi, G Kim, K Prybylowski, B Vissel, S Vicini (2002) Functional expression of distinct NMDA channel subunits tagged with green uorescent protein in hippocampal neurons in culture, 306-318. In Neuropharmacology.

Download PDF (2.19 MB)

Seigo Tanaka, Masanori Takehashi, Naomi Matoh, Shinya Iida, Tomoki Suzuki, Shiroh Futaki, Hirofumi Hamada, Eliezer Masliah, Yukio Sugiura, Kunihiro Ueda (2002) Generation of reactive oxygen species and activation of NF-jB by non-Ab component of Alzheimer’s disease amyloid, 305-315.

Download PDF (467.83 KB)

Derrick E Fouts, Robert B Abramovitch, James R Alfano, Angela M Baldo, Robin Buell, Samuel Cartinhour, Arun K Chatterjee, Michelle L Gwinn, Sondra G Lazarowitz, Nai-Chun Lin, Gregory B Martin, Amos H Rehm, David J Schneider, Xiaoyan Tang, Alan Collmer (2002) Genomewide identification of Pseudomonas syringae pv. tomato DC3000 promoters controlled by the HrpL alternative sigma factor, 2275-2280. In Reactions 99 (4).

Download PDF (170.62 KB)

Alan Collmer, Magdalen Lindeberg, Tanja Petnicki-Ocwieja, David J Schneider, James R Alfano (2002) Genomic mining type III secretion system effectors in Pseudomonas syringae yields new picks for all TTSS prospectors, 462-469. In Trends in Microbiology 10 (10).

Download PDF (90.46 KB)

NMDA Receptors (2002) Hunting for Excitement: NMDA Receptors in Huntington’s Disease, 841-842. In Neuron.

Download PDF (33.38 KB)

Melinda M Zeron, Oskar Hansson, Nansheng Chen, Cheryl L Wellington, Blair R Leavitt, Patrik Brundin, Michael R Hayden, Lynn A Raymond, Kinsmen Laboratory, Lund Sweden, Molecular Medicine, Medical Genetics, British Columbia Vancouver, British Columbia (2002) Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington’s Disease, 849-860. In Neuron.

Download PDF (376.5 KB)

Hidenori Taru, Ko-ichi Iijima, Momoko Hase, Yutaka Kirino, Yoshimasa Yagi, Toshiharu Suzuki (2002) Interaction of Alzheimer’s ␤ -Amyloid Precursor Family Proteins with Scaffold Proteins of the JNK Signaling Cascade*, 20070 -20078. In Molecular Biology 277 (22).

Download PDF (528.95 KB)

BRYCE VISSEL, JOHANNES J KRUPP, STEPHEN F HEINEMANN, GARY L WESTBROOK (2002) Intracellular Domains of NR2 Alter Calcium-Dependent Inactivation of, 595-605. In Mol Pharmacol 61 (3).

Download PDF (574.13 KB)

Mathijs Voorhoeve, Reuven Agami (2002) Knockdown stands up, 1-2. In In vivo 7799 (02).

Download PDF (46.87 KB)

Fabrizio Gardoni, Camilla Bellone, Barbara Viviani, Marina Marinovich, Elena Meli, Domenico E Pellegrini-Giampietro, Flaminio Cattabeni, Monica Di Luca (2002) Lack of PSD-95 drives hippocampal neuronal cell death through activation of an aCaMKII transduction pathway. In European Journal of Neuroscience.

Download PDF (607.31 KB)

Ryota Hashimoto, Christopher Hough, Takanobu Nakazawa, Tadashi Yamamoto, De-Maw Chuang (2002) Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation, 589-597. In New York.

Download PDF (380.79 KB)

Alzheimer Ab (2002) Mechanism of membrane depolarization caused by the Alzheimer Ab1–42 peptide, 1197-1203. In Biochemical and Biophysical Research Communications.

Download PDF (261.6 KB)

C Fink, F Morgan, L M Loew, A Smith, A Brownawell, I G Macara, P R Clarke, C Klebe, A Wittinghofer, E Karsenti, M Ormo, A E Smith, K J Zaal, Virtual Cell, V C Cordes, S Reidenvach, W D Clarkson, H M Kent, M Stewart, K M Lounsbury, S A Richards, K L Carey, H Nishitani, E Izaurralde, U Kutay, C Vonkobbe, I W Mattaj, D Gorlich, B Senger, L F Pemberton, J S Rosenblum, G Blobel, Biomedical Imaging Technology (2002) Modulation of NMDA Receptor– Dependent Calcium In ux and Gene Expression Through EphB Receptors, 491-495. In Science 295 (January).

Download PDF (379.55 KB)

J Miguel, A Alvarez, R Cacabelos, G Quack (2002) N europrotection by memantine against neurodegeneration induced by b-amyloid(1–40), 210-221. In Brain Research.

Download PDF (1.62 MB)

Frank J E Vajda (2002) Neuroprotection and neurodegenerative disease, 4-8. In Journal of Clinical Neuroscience 9 (May 2001).

Download PDF (118.86 KB)

Rami Yaka, Claire Thornton, Alicia J Vagts, Khanhky Phamluong, Antonello Bonci, Dorit Ron, Experimental Procedures (2002) NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1, 1-6. In Neurobiology 99 (8).

Download PDF (367 KB)

Download PDF (501.42 KB)

Marja Ja (2002) Programmed cell death: many ways for cells to die decently, 480-488. In Annals of Medicine.

Download PDF (376.76 KB)

John J Woodward (2002) Prostacyclin-induced rundown of N-methyl-, 598-604. In Journal of Neurochemistry.

Download PDF (316.11 KB)

RODNEY P GUTTMANN, S E T SOKOL, DANA L BAKER, KELLY L SIMPKINS, YINA DONG, David R Lynch (2002) Proteolysis of the, 1023-1030. In Pharmacology 302 (3).

Download PDF (238.59 KB)

Philip Washbourne, Jennie E Bennett, Kimberley McAllister (2002) Rapid recruitment of NMDA receptor transport packets to nascent synapses, 751-759. In Group.

Download PDF (1.39 MB)

Ritchie Williamson, Timothy Scales, Bruce R Clark, Graham Gibb, Hugh Reynolds, Stuart Kellie, Ian N Bird, Ian M Varndell, Paul W Sheppard, Ian Everall, Brian H Anderton (2002) Rapid Tyrosine Phosphorylation of Neuronal Proteins Including Tau and Focal Adhesion Kinase in Response to Amyloid- ␤ Peptide Exposure: Involvement of Src Family Protein Kinases, 10-20. In Journal of Neuroscience 22 (1).

Download PDF (341.53 KB)

AE West, EC Griffith, ME Greenberg (2002) Regulation of transcription factors by neuronal activity. In Nature Reviews Neuroscience 3 (December).

http://www.nature.com/nrn/journal/v3/...

Download PDF (2.2 MB)

Kate Prybylowski, ZHANYAN FU, Gabriele Losi, Lynda M Hawkins, JIANHONG LUO, Kai Chang, Robert J Wenthold, STEFANO VICINI (2002) Relationship between Availability of NMDA Receptor Subunits and Their Expression at the Synapse, 8902-8910. In Journal of Neuroscience 22 (20).

Download PDF (254 KB)

K E Y Words (2002) Repeated Cocaine Administration Differentially Affects NMDA Receptor Subunit (NR1, NR2A-C) mRNAs in Rat Brain, 157-169. In Behavioral assessment 169 (October 2001).

Download PDF (1.15 MB)

K D Holmes, P Mattar, D R Marsh, V Jordan, L C Weaver, G A Dekaban (2002) The C-terminal C1 cassette of the N-methyl-, 1152-1165. In Journal of Neurochemistry.

Download PDF (771.09 KB)

Karen Ritchie, Simon Lovestone, The Lancet (2002) The dementias, 1759-1766. In The Lancet.

Download PDF (103.35 KB)

T H E MOLECULAR BASIS O F CaMKII FUNCTIONSYNAPTICBEHAVIOURAL MEMORY (2002) THE MOLECULAR BASIS OF CaMKII FUNCTION IN SYNAPTIC AND BEHAVIOURAL MEMORY. In Neuroscience 3 (March).

Download PDF (4.01 MB)

T H E PENN (2002) The penn. In Wall Street Journal.

Download PDF (747.85 KB)

Michelle Aarts, Yitao Liu, Lidong Liu, Shintaro Besshoh, Mark Arundine, James W Gurd, Yu-Tian Wang, Michael W Salter, Michael Tymianski (2002) Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor– PSD-95 Protein Interactions, 846-850. In Science 298 (October).

Download PDF (1.45 MB)

X Bi, C M Gall, J Zhou, G Lynch (2002) Uptake and pathogenic effects of amyloid beta peptide 1^42 are enhanced by integrin antagonists and blocked by nmda receptor antagonists, 827-840. In Science 112 (4).

Download PDF (902.58 KB)

Antonella Riccio, David D Ginty (2002) What a privilege to reside at the synapse: NMDA receptor signaling to CREB. In Group.

Download PDF (516.36 KB)

Chun-I Sze, Hong Bi, Christopher M Filley, Lee J Martin (2001) -aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer’s disease, 151-159. In Journal of the Neurological Sciences.

Download PDF (615.68 KB)

Stephen M Fitzjohn, Robin A Morton, Frederick Kuenzi, Thomas W Rosahl, Mark Shearman, Huw Lewis, David Smith, David S Reynolds, Ceri H Davies, Graham L Collingridge, Guy R Seabrook (2001) Age-Related Impairment of Synaptic Transmission But Normal Long-Term Potentiation in Transgenic Mice that Overexpress the Human APP695SWE Mutant Form of Amyloid Precursor Protein, 4691-4698. In Ratio 21 (13).

Download PDF (513.7 KB)

Petra Nowotny (2001) Alzheimer Disease, 1-6. In LIFE SCIENCES.

Download PDF (286 KB)

(2001) Alzheimer’s disease and Aβ toxicity: from top to bottom. In Neuroscience.

Download PDF (388.1 KB)

Dennis J Selkoe, Neuropathological Phenotype, Disease A Neuritic, Cell Biology, Amyloid Precursor Protein A Expression, A P P B Traf, A P P C Inferred, Familial Alzheimer, Disease A Familial, A D C Missense, A D E Other, Genotype-to-Phenotype Conversions, Disease A APP, Central Role, Intramembranous Proteolysis A Cell, A P P C Presenilin, The Complex, Neurotoxic Cascade, Disease A Clues, A D D Free, Preventing Alzheimer, Disease A Remaining, Proteins Genes (2001) Alzheimer’s Disease: Genes, Proteins, and Therapy, 741-766. In PERSPECTIVE 81 (2).

Download PDF (650 KB)

Derek B Scott, Thomas A Blanpied, Geoffrey T Swanson, Chi Zhang, Michael D Ehlers (2001) An NMDA Receptor ER Retention Signal Regulated by Phosphorylation and Alternative Splicing, 3063-3072. In Journal of Neuroscience 21 (9).

Download PDF (881.42 KB)

Shing Fai Chan, Nikolaus J Sucher (2001) An NMDA Receptor Signaling Complex with Protein Phosphatase 2A, 7985-7992. In Science and Technology 21 (20).

Download PDF (351 KB)

With Special Emphasis (2001) Biological Markers for Alzheimer’s Disease, 1-69. In Medicine.

Download PDF (245.87 KB)

G L Rintoul, L A Raymond, K G Baimbridge (2001) Calcium buffering and protection from excitotoxic cell death by exogenous calbindin-D28k in HEK 293 cells, 277-287. In Cell Calcium.

Download PDF (275.79 KB)

Thomas Crump, Keith S Dillman, Ann Marie Craig (2001) CAMP-Dependent Protein Kinase Mediates Activity-Regulated Synaptic Targeting of NMDA Receptors, 5079-5088. In Journal of Neuroscience 21 (14).

Download PDF (3.84 MB)

New Jersey (2001) Cell Differentiation In Vitro: Model Systems. In LIFE SCIENCES.

Download PDF (101.24 KB)

Graham Knott, Zoltan Molnar (2001) Cells of the Nervous System. In Blood Vessels.

Download PDF (625 KB)

Gennady Ermak, Todd E Morgan, Kelvin J A Davies (2001) Chronic Overexpression of the Calcineurin Inhibitory Gene, 38787-38794. In Molecular Biology 276 (42).

Download PDF (565.06 KB)

Atilla D Kova, Gvido Cebers, Aleta Cebere, Tiago Moreira, Sture Liljequist (2001) Cortical and Striatal Neuronal Cultures of the Same Embryonic Origin Show Intrinsic Differences in Glutamate Receptor Expression and Vulnerability to Excitotoxicity, 47- 62. In Experimental Neurology.

Download PDF (863 KB)

Gunnar K Gouras (2001) Current theories for the molecular and cellular pathogenesis of Alzheimer’s disease, 1-11..

Download PDF (494 KB)

Gunnar K Gouras (2001) Current theories for the molecular and cellular pathogenesis of Alzheimer’s disease, 1-11..

Download PDF (494 KB)

Lucia Pasti, Micaela Zonta, Tullio Pozzan, STEFANO VICINI, Giorgio Carmignoto (2001) Cytosolic Calcium Oscillations in Astrocytes May Regulate Exocytotic Release of Glutamate, 477-484. In Journal of Neuroscience 21 (2).

Download PDF (869.78 KB)

Cristina Rego, Jeremy J Lambert, David G Nicholls (2001) Developmental pro®le of excitatory GABA, 477-482. In Ratio 12 (3).

Download PDF (216.85 KB)

Sridhar Varadarajan, Jaroslaw Kanski, Marina Aksenova, Christopher Lauderback, Allan Butterfield (2001) Different Mechanisms of Oxidative Stress and Neurotoxicity for Alzheimer′s A (1-42) and A (25-35), 5625-5631. In Stress: The International Journal on the Biology of Stress.

Download PDF (238 KB)

Daniel R Marsh, Kevin D Holmes, Gregory A Dekaban, Lynne C Weaver (2001) Distribution of an NMDA receptor:GFP fusion protein in sensory neurons is altered by a C-terminal construct, 23-33. In Plasmid.

Download PDF (682.51 KB)

Mark P Mattson, Sic L Chan (2001) Dysregulation of Cellular Calcium Homeostasis in Alzheimer’s Disease, 205-224. In Journal of Molecular Neuroscience.

Download PDF (823.02 KB)

Shigeo Uchino, Wakako Watanabe, Takeshi Nakamura, Satoshi Shuto, Yuji Kazuta, Akira Matsuda, Sadayo Nakajima-Iijima, Yoshihisa Kudo, Shinichi Kohsaka, Masayoshi Mishina (2001) Establishment of CHO cell lines expressing four N-methyl-, 117-122..

Download PDF (297.54 KB)

Marcel Leist (2001) Four deaths and a funeral: from caspases to alternative mechanisms, 1-10. In Cell 2 (August).

Download PDF (706.2 KB)

Saint Andrieu, P C May, L D Altstiel, M H Bender, L N Boggs, T C Britton, J C Clemens, D L Czilli, D K Dieckman, J J Droste, K S Fuson, B D Gitter, P A Hyslop, E M Johnstone, Li, S P Little, T E Mabry, F D Miller, B Ni, J S Nissen, W J Porter, B D Potts, J K Reel, D Stephenson, Su, L A Shipley, C A Whitesitt, T Yin, J E AUDIA (2001) Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain, 173-181. In City.

Download PDF (627.66 KB)

N Janssens, A S J Lesage (2001) Glutamate receptor subunit expression in primary neuronal and secondary glial cultures, 1457-1474. In Proteins.

Download PDF (988.26 KB)

PROPERTY COMMON T O MOST CYCLIN-DEPENDENT KINASE INHIBITORS (2001) Indirubins Inhibit Glycogen Synthase Kinase-3 ␤ and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer’s Disease, 251-260. In Molecular Biology 276 (1).

Download PDF (930.31 KB)

What Are Ion Channels, Why Do Cells Need Them (2001) Ion Channels. In Ion Channels.

Download PDF (358 KB)

Departmento Biolog, Centro Nacional, CSIC Campus, Spain Correspondence, Elsevier Science Ltd (2001) Mechanisms of Ca 2+ -dependent transcription, 312-319. In Current Opinion in Neurobiology.

Download PDF (94.78 KB)

Cristina Rego, Manus W Ward, David G Nicholls (2001) Mitochondria Control AMPA/Kainate Receptor-Induced Cytoplasmic Calcium Deregulation in Rat Cerebellar Granule Cells, 1893-1901. 21 (6).

Download PDF (190.13 KB)

R Wagey, J Hu, S L Pelech, L A Raymond, C Krieger (2001) Modulation of NMDA-mediated excitotoxicity by protein kinase C, 715-726. In Journal of Neurochemistry.

Download PDF (770.27 KB)

Liqun Bai, Hua Xu, James F Collins, Fayez K Ghishan (2001) Molecular and Functional Analysis of a Novel Neuronal Vesicular Glutamate Transporter*, 36764 -36769. In Molecular Biology 276 (39).

Download PDF (546.33 KB)

Rita Sattler, Michael Tymianski (2001) Molecular Mechanisms of Glutamate Receptor-Mediated Excitotoxic Neuronal Cell Death, 107-129. In Molecular Neurobiology 24 (1).

Download PDF (166.38 KB)

Baljit S Khakh (2001) Molecular physiology of p2x receptors and atp signalling at synapses. In Neuroscience 2 (March).

Download PDF (2.07 MB)

Mayumi Nishi, Heather Hinds, Hai-Ping Lu, Mitsuhiro Kawata, Yasunori Hayashi (2001) Motoneuron-Speciﬁc Expression of NR3B, a Novel NMDA-Type Glutamate Receptor Subunit That Works in a Dominant-Negative Manner, 1-6. In Journal of Neuroscience.

Download PDF (381 KB)

Edinburgh EH, Los Angeles, Elsevier Science Ltd (2001) Multiprotein complex signaling and the plasticity problem, 363-368. In Current Opinion in Neurobiology.

Download PDF (136 KB)

Mutant Huntingtin Enhances Excitotoxic Cell Death (2001) Mutant Huntingtin Enhances Excitotoxic Cell Death, 41-53. In Molecular and Cellular Neuroscience.

Download PDF (353.07 KB)

Article Contents (2001) Myelin and Action Potential Propagation. In LIFE SCIENCES.

Download PDF (417 KB)

Article Contents (2001) Myelin and Action Potential Propagation. In LIFE SCIENCES.

Download PDF (417 KB)

MP Mattson, W Duan, WA Pedersen, C Culmsee (2001) Neurodegenerative disorders and ischemic brain diseases, 69-81. In Apoptosis 6 (1).

http://www.springerlink.com/index/tr7...

Download PDF (416.65 KB)

Alka Agarwal-Mawal, Hemant K Paudel (2001) Neuronal Cdc2-like Protein Kinase (Cdk5/p25) Is Associated with Protein Phosphatase 1 and Phosphorylates Inhibitor-2*, 23712-23718. In Molecular Biology 276 (26).

Download PDF (268.73 KB)

Janice K Parks, Trisha S Smith, Patricia A Trimmer, James P Bennett Jr, Davis Parker Jr (2001) Neurotoxic Ab peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro, 1050-1056. In Journal of Neurochemistry.

Download PDF (616.33 KB)

Keiko Tominaga-Yoshino, Taichi Uetsuki, Kazuaki Yoshikawa, Akihiko Ogura (2001) Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA, 121-130. In Brain Research.

Download PDF (1.77 MB)

Carlos Cepeda, Marjorie A Ariano, Christopher R Calvert, Jorge Flores-Herna, Scott H Chandler, Blair R Leavitt, Michael R Hayden, Michael S Levine (2001) NMDA Receptor Function in Mouse Models of Huntington Disease, 525-539. In Journal of Neuroscience Research 539 (July).

Download PDF (330.28 KB)

David R Lynch, RODNEY P GUTTMANN (2001) NMDA Receptor Pharmacology: Perspectives from Molecular Biology, 215-231. In Current Drug Targets.

Download PDF (185.3 KB)

C Castellano, V Cestari, A Ciamei (2001) NMDA Receptors and Learning and Memory Processes, 273-283. In Current Drug Targets.

Download PDF (165.57 KB)

Makoto Urushitani, Tomoki Nakamizo, Ryotaku Inoue, Hideyuki Sawada, Takeshi Kihara, Kazuhiro Honda, Akinori Akaike, Shun Shimohama (2001) No title., 377-387. In Journal of Neuroscience Research 387 (September 2000).

Download PDF (563.27 KB)

William L Klein, Grant A Krafft, Caleb E Finch (2001) Oligomers: the Targeting small Aβ solution to an Alzheimer’s disease conundrum?, 219-224. In Trends in Neurosciences 24 (4).

Download PDF (172.39 KB)

David Schubert, Dana Piasecki (2001) Oxidative Glutamate Toxicity Can Be a Component of the Excitotoxicity Cascade, 7455-7462. In Trends Pharmacol Sci 21 (19).

Download PDF (203 KB)

Kanae Ando, Ko-ichi Iijima, James I Elliott, Yutaka Kirino, Toshiharu Suzuki (2001) Phosphorylation-dependent Regulation of the Interaction of Amyloid Precursor Protein with Fe65 Affects the Production of ␤ -Amyloid*, 40353-40361. In Molecular Biology 276 (43).

Download PDF (363.67 KB)

Glyn Stacey (2001) Primary Cell Cultures and Immortal Cell Lines. In LIFE SCIENCES.

Download PDF (101.37 KB)

N R Lemoine (2001) Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors, 256-264. In Cell Death and Differentiation.

Download PDF (386.69 KB)

Rebecca Ho, Daniela Ortiz, Thomas B Shea (2001) Promotes calcium in ux and neurodegeneration via stimulation of L voltage-sensitive calcium channels rather than NMDA channels in cultured neurons, 479-483..

Download PDF (50 KB)

Matthew R Hynd, Heather L Scott, Peter R Dodd (2001) Receptor NR1 subunit mRNA expression in Alzheimer's disease, 175-182. In Journal of Neurochemistry.

Download PDF (504.95 KB)

Bing-Sheng Li, Miao-Kun Sun, Lei Zhang, Satoru Takahashi, Lucia Vinade, Ashok B Kulkarni, Roscoe O Brady, Harish C Pant (2001) Regulation of NMDA receptors by cyclin-dependent kinase-5. In NEUROBIOLOGY 98 (22).

Download PDF (589.8 KB)

Yan Zhang, Richard McLaughlin, Cynthia Goodyer (2001) Selective cytotoxicity of intracellular amyloid ␤ peptide 1–42 through p53 and Bax in cultured primary human neurons, 519-529. In The Journal of Cell Biology.

Download PDF (566.45 KB)

Milla Koistinaho, Michael Ort, Jose M Cimadevilla, Roman Vondrous, Barbara Cordell, Jari Koistinaho, Jan Bures, Linda S Higgins (2001) Specific spatial learning deficits become severe with age in ␤ -amyloid precursor protein transgenic mice that harbor diffuse ␤ -amyloid deposits but do not form plaques, 14675-14680. In NEUROBIOLOGY 98 (25).

Download PDF (239.29 KB)

Anne Stephenson (2001) Subunit Characterization of NMDA Receptors, 233-239. In Current Drug Targets.

Download PDF (150.25 KB)

Mary B Kennedy, Pat Manzerra (2001) Telling tails, 12323-12324. In Pharmacol Rev 98 (22).

Download PDF (170.83 KB)

Philippe Cupers, Isabelle Orlans, Katleen Craessaerts, Wim Annaert, Bart De Strooper (2001) The amyloid precursor protein (APP)-cytoplasmic fragment generated by g-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture, 1168-1178. In Journal of Neurochemistry.

Download PDF (465.82 KB)

A C Rego, D G Nicholls (2001) The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells, 995-1003. In Cell Death and Differentiation.

Download PDF (767.84 KB)

Review Article, Ricardo B Maccioni, Juan P Mu, Luis Barbeito (2001) The Molecular Bases of Alzheimer’s Disease and Other Neurodegenerative Disorders, 367-381. In Archives of Medical Research.

Download PDF (369 KB)

Jaime Renart, Margarita DI (2001) The NR1 subunit of the N-methyl-, 539-547. In Society.

Download PDF (281.86 KB)

Ricardo B Maccioni, Carola Otth, Ilona I Concha, Juan P Mun, Cdk MAPs (2001) The protein kinase Cdk5, 1518-1527. In Eur J Biochem.

Download PDF (438.36 KB)

Richard Dargusch, Dana Piasecki, Shirlee Tan, Yuanbin Liu, David Schubert (2001) The role of Bax in glutamate-induced nerve cell death, 295-301. In Journal of Neurochemistry.

Download PDF (424.25 KB)

FEBS Meeting (2001) The role of protein phosphorylation in human health and disease, 5001-5010. In Eur J Biochem.

Download PDF (662.33 KB)

Christopher Janus, David Westaway (2001) Transgenic mouse models of Alzheimer’s disease, 873 - 886. In Physiology & Behavior.

Download PDF (180.38 KB)

Roger Ward (2001) Vertebrate Central Nervous System `, 1-6. In LIFE SCIENCES.

Download PDF (132 KB)

John H Morrison (2001) Which synapses are affected in aging and what is the nature of their vulnerability? A commentary on “life span and synapses: will there be a primary senile dementia?”, 349 -350. In Neurobiology of Aging.

Download PDF (36.23 KB)

Norifusa J Anegawa, RODNEY P GUTTMANN, Elfrida R Grant, Rene Anand, Jon Lindstrom, David R Lynch (2000) -aspartate receptor mediated toxicity in nonneuronal cell lines: characterization using uorescent measures of cell viability and reactive oxygen species production. In Molecular Brain Research.

Download PDF (3.3 MB)

Nathalie Sans, Ronald S Petralia, Ya-Xian Wang, Jaroslav Blahos II, Johannes W Hell, Robert J Wenthold (2000) A Developmental Change in NMDA Receptor-Associated Proteins at Hippocampal Synapses, 1260-1271. 20 (3).

Download PDF (818.79 KB)

Rathna Nath, Michele Scott, Ravi Nadimpalli, Rita Gupta, Kevin K W Wang (2000) Activation of apoptosis-linked caspase(s) in NMDA-injured brains in neonatal rats, 119-126. In Neurochemistry International.

Download PDF (189.07 KB)

Silke Lankiewicz, Marc Luetjens, Nguyen Truc Bui, Aaron J Krohn, Monika Poppe, Greg M Cole, Takaomi C Saido, Jochen H M Prehn (2000) Activation of Calpain I Converts Excitotoxic Neuron Death into a Caspase-independent Cell Death*, 17064 -17071. 275 (22).

Download PDF (315.6 KB)

Piecing Together (2000) Alzheimer’s. In Scientific American.

Download PDF (553.22 KB)

Rachael L Neve, Donna L McPhie, Yuzhi Chen (2000) Alzheimer’s disease: a dysfunction of the amyloid precursor protein 1, 54-66. In World Wide Web.

Download PDF (859.8 KB)

Distinct AMPA (2000) AMPA and NMDA receptors: similarities and differences in their synaptic distribution, 337-341. In Current Opinion in Neurobiology.

Download PDF (77 KB)

Hoau-Yan Wang, Daniel H S Lee, Coralie B Davis, Richard P Shank (2000) Amyloid Peptide A ␤ 1– 42 Binds Selectively and with Picomolar Af nity to ␣ 7 Nicotinic Acetylcholine Receptors.

Download PDF (89 KB)

Kiyofumi Yamada, Toshitaka Nabeshima (2000) Animal models of Alzheimer's disease and evaluation of anti-dementia drugs. In Pharmacology & Therapeutics.

Download PDF (357.15 KB)

C Behl (2000) Apoptosis and Alzheimer’s disease, 1325-1344. In J Neural Transm.

Download PDF (158.01 KB)

SHORT REVIEW (2000) Apoptosis and the Nervous System. In Comparative.

Download PDF (296.77 KB)

Although TUNEL (2000) Apoptosis in Alzheimer’s disease—an update, 9-16. In Apoptosis 5 (1).

Download PDF (249.26 KB)

Mark P Mattson (2000) Apoptosis in neurodegenerative disorders, 120-129. In Cell 1 (October).

Download PDF (1.61 MB)

William R A Brown, Joe Mee, Ming Hong Shen (2000) Artificial chromosomes: ideal vectors?, 218-223. In Science 18 (May).

Download PDF (113.75 KB)

W Timmerman, G Laskay, B To, M Sasva, C Ko, J B Sebens, T Harkany, K Soo, B Penke, P G M Luiten, J Korf, C Nyakas, M Zara (2000) B-Amyloid neurotoxicity is mediated by a glutamate- triggered excitotoxic cascade in rat nucleus basalis, 2735-2745. In European Journal of Neuroscience.

Download PDF (917.9 KB)

Kevin K W Wang (2000) Calpain and caspase: can you tell the difference?. 2 (1990).

Download PDF (149.46 KB)

K E Y FUNCTIONAL INTERACTION BETWEEN INHIBITOR-, T H E TYPE, PROTEIN PHOSPHATASE CATALYTIC SUBUNIT (2000) Cellular Mechanisms Regulating Protein Phosphatase-1, 18670 -18675. In Molecular Biology 275 (25).

Download PDF (228.12 KB)

Amina Ra, Anne Bernard, Igor Medina, Henri Gozlan, Michel Khrestchatisky (2000) Characterization in Cultured Cerebellar Granule Cells and in the Developing Rat Brain of mRNA Variants for the NMDA Receptor 2C Subunit.

Download PDF (642.21 KB)

Bart De Strooper, Wim Annaert (2000) COMMENTARY Proteolytic processing and cell biological functions of the amyloid precursor protein, 1857-1870. In Journal of Cell Science.

Download PDF (129.23 KB)

Marc Luetjens, Nguyen Truc Bui, Bernd Sengpiel, Gudrun Mu, Monika Poppe, Aaron J Krohn, Elke Bauerbach, Josef Krieglstein, Jochen H M Prehn (2000) Delayed Mitochondrial Dysfunction in Excitotoxic Neuron Death: Cytochrome, 5715-5723. In Journal of Neuroscience 20 (15).

Download PDF (562.65 KB)

Gordon W Glazner, Mark P Mattson (2000) Differential Effects of BDNF, ADNF9, and TNF␣ on Levels of NMDA Receptor Subunits, Calcium Homeostasis, and Neuronal Vulnerability to Excitotoxicity, 442-452. In Experimental Neurology.

Download PDF (471.9 KB)

Rita Sattler, Zhigang Xiong, Wei-Yang Lu, John F MacDonald, Michael Tymianski (2000) Distinct Roles of Synaptic and Extrasynaptic NMDA Receptors in Excitotoxicity, 22-33. In Journal of Neuroscience 20 (1).

Download PDF (632.58 KB)

George Koob (2000) Drug Addiction, 543-545. In Neurobiology of Disease.

Download PDF (98.18 KB)

C J Wilson, D A Hoffman, J C Magee, C M Colbert, D Johnston, P C Schwindt, W E Crill, S Cash, R Yuste, A D Reyes, E W Rubel, W J Spain, N E Schoppa, G L Westbrook, A Majewska, K Holthoff, E P Cook, W Rall, R E Burke, G T Bruggencate, S Redman, B Walmsley, G M Shepherd, T S Reese, M W Brightman, UCLA Press, Los Angeles, F Engert, T Bonhoeffer, M Maletic, R Malinow, K Svoboda, R D Stratford, A J R Mason, A U Larkman, G Major, J J B Jack, R Durbin, C Miall, C Mitchson, D Pare, E Shink, H Gaudreau, A Destexhe, E J Lang, M Hausser, B A Clark, R J Douglas, K A C Martin, D Whitteridge, L J Borg, C Monier, Fregnac, J Copeland, J J Hop, Fujita, C Nicholson, R Llinas, G Laurent, K J Seymour, K Johnson, B W Mel, D L Ruderman, K A Archie, C Koch, New York, A Borst, M Egelhaaf, E C Sobel, D W Tank, F Helmchen, W Denk, A Kamondi, L Acsády, G Buzsaki, J Haag, S Single, M London, C Meunier, I Segev, H C Tuckwell, H Markram, M Tsodyks, A Zador, B Pearlmutter, M Siegel, E Marder, L F Abbott, M Stemmler, L J DeFelice, E Wanke, F Conti, E Schneidman, B Freedman, A Manwani, J A White, J T Rubinstein, A R Kay, F Rieke, D Warland, W Bialek, M I T Press (2000) Endrites 40., 750-754. In Science 290 (October).

Download PDF (348.33 KB)

M.K. Ahlijanian, N.X. Barrezueta, R.D. Williams, Amy Jakowski, K.P. Kowsz, Sheryl McCarthy, Timothy Coskran, Anthony Carlo, P.A. Seymour, J.E. Burkhardt, others (2000) Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5, 2910. In Proceedings of the National Academy of Sciences of the United States of America 97 (6).

http://www.pnas.org/content/97/6/2910...

Download PDF (503.53 KB)

Atsushi Takeda, Mark A Smith, Jesus Avila, Akihiko Nunomura, Sandra L Siedlak, Xiongwei Zhu, George Perry, Lawrence M Sayre (2000) In Alzheimer’s Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of ␶ Induced by 4-Hydroxy-2-Nonenal Modi cation, 1234-1241. In J Neurochem.

Download PDF (1.19 MB)

Donald P Cain, Koorosh Ighanian, Francis Boon (2000) Individual and combined manipulation of muscarinic, NMDA, and benzodiazepine receptor activity in the water maze task: implications for a rat model of Alzheimer dementia, 125 - 137. In Behavioural Brain Research.

Download PDF (226.7 KB)

Lalitha Tenneti, Stuart A Lipton (2000) Involvement of Activated Caspase-3-Like Proteases in N-Methyl-, 134-142.

Download PDF (289.78 KB)

Pergamon Pii, D G FUJIKAWA, S S SHINMEI, B Cai (2000) Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal dna cleavage: implications for programmed cell death mechanisms, 41-53. In Neuroscience 98 (1).

Download PDF (675.35 KB)

K E Y Words (2000) Key words:, 212-221. In Leukemia.

Download PDF (191.04 KB)

Guest Editors, Enrique Cadenas, Kelvin J A Davies TRIGGERINGMODULATION O F APOPTOSIS B Y OXIDATIVE STRESS (2000) Lars Ernster Commemorative Issue, 323-333. In Science 29 (00).

Download PDF (445.48 KB)

A Bradbury, D Simmons, J Slater, M Crouch (2000) Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis, 79-92. In Journal of Immunological Methods.

Download PDF (724.61 KB)

Samantha L Budd, Lalitha Tenneti, Timothy Lishnak, Stuart A Lipton (2000) Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons, 6161-6166. In NEUROBIOLOGY 97 (11).

Download PDF (248 KB)

Manus W Ward, Cristina Rego, Bruno G Frenguelli, David G Nicholls (2000) Mitochondrial Membrane Potential and Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells, 7208-7219. 20 (19).

Download PDF (215.79 KB)

DELETION ANALYSIS O F PROTEIN-PROTEIN INTERACTION DOMAINS (2000) Modulation of Amyloid Precursor Protein Metabolism by X11 ␣ /Mint-1, 39302-39306. In J Neurosci 275 (50).

Download PDF (144.66 KB)

Masahiro Kawahara, Yoichiro Kuroda (2000) Molecular mechanism of neurodegeneration induced by Alzheimer’s ␤ -amyloid protein: Channel formation and disruption of calcium homeostasis, 389 -397. In Brain Research Bulletin 53 (4).

Download PDF (834.33 KB)

REVIEW Rita Sattler, Michael Tymianski (2000) Molecular mechanisms of calcium-dependent excitotoxicity, 3-13. In J Mol Med.

Download PDF (253.67 KB)

Jun Liu, Jun WU, Carey OLIVER, Shirish SHENOLIKAR, David L Brautigan (2000) Mutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunit, 77-82..

Download PDF (168.11 KB)

Ko-ichi Iijima, Kanae Ando, Shizu Takeda, Yasushi Satoh, Tatsunori Seki, Shigeyoshi Itohara, Paul Greengard, Yutaka Kirino, Angus C Nairn, Toshiharu Suzuki (2000) Neuron-Speci c Phosphorylation of Alzheimer’s ␤ -Amyloid Precursor Protein by Cyclin-Dependent Kinase 5. In Pharmacia.

Download PDF (1.64 MB)

Ming-Sum Lee, Young T Kwon, Mingwei Li, Junmin Peng, Robert M Friedlander, Li-Huei Tsai (2000) Neurotoxicity induces cleavage of p35 to p25 by calpain. In NATURE 405 (May).

Download PDF (356.06 KB)

Jeroo D Sinor, Shen Du, Sriram Venneti, Rachel C Blitzblau, Daniel N Leszkiewicz, Paul A Rosenberg, Elias Aizenman (2000) NMDA and Glutamate Evoke Excitotoxicity at Distinct Cellular Locations in Rat Cortical Neurons, 8831-8837. In Journal of Neuroscience 20 (23).

Download PDF (323.72 KB)

Yves Christen (2000) Oxidative stress and Alzheimer disease 1,2. In Am J Clin Nutr.

Download PDF (58.23 KB)

P I I SOO, December IO (2000) Pii soo24-3205(00)00511-7, 1879-1892. In Life Sciences 66 (19).

Download PDF (1013.14 KB)

Robert H Scannevin, Richard L Huganir (2000) Postsynaptic organization and regulation of excitatory synapses. In Neuroscience 1 (November).

Download PDF (850.66 KB)

Paul E Fraser, Dun-Sheng Yang, Gang Yu, Lyne Le, Masaki Nishimura, Shigeki Arawaka, Louise C Serpell, Ekaterina Rogaeva, Peter St George-Hyslop (2000) Presenilin structure, function and role in Alzheimer disease ¨. In Neurodegenerative Diseases.

Download PDF (674.95 KB)

St George-Hyslop, Experimental Procedures (2000) Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically, 12822-12827. In In Vitro 97 (23).

Download PDF (266.87 KB)

Holger Husi, Malcolm A Ward, Jyoti S Choudhary, Walter P Blackstock, Seth G N Grant (2000) Proteomic analysis of NMDA receptor–adhesion protein signaling complexes, 661-669. In America.

Download PDF (282.76 KB)

Douglas L Anders, Tana Blevins, Corigan T Smothers, John J Woodward (2000) Reduced Ethanol Inhibition of, 15019 -15024. In Molecular Biology 275 (20).

Download PDF (176.08 KB)

Michal Hetman, Jane E Cavanaugh, David Kimelman, Zhengui Xia (2000) Role of Glycogen Synthase Kinase-3 ␤ in Neuronal Apoptosis Induced by Trophic Withdrawal, 2567-2574. In Journal of Neuroscience 20 (7).

Download PDF (366 KB)

Gerald A Rameau, Yukio Akaneya, Ling-Yu Chiu, Edward B Ziff (2000) Role of NMDA receptor functional domains in excitatory cell death, 2255-2266. In New York.

Download PDF (218.86 KB)

Experimental Genetics Group, Human Genetics, Belgium Received (2000) Single and multiple transgenic mice as models for Alzheimer's disease, 305-312. In Progress in Neurobiology.

Download PDF (117.99 KB)

Paula Moreira, Raquel Seic, Maria Sancha Santos, Catarina R Oliveira (2000) Susceptibility to ␤-Amyloid-Induced Toxicity Is Decreased in Goto-Kakizaki Diabetic Rats: Involvement of Oxidative Stress, 383-391. In Experimental Neurology.

Download PDF (133.06 KB)

Dan Luo, Mark Saltzman (2000) Synthetic DNA delivery systems. In NATURE BIOTECHNOLOGY.

Download PDF (210.59 KB)

Roger Tremblay, Balu Chakravarthy, Kimberley Hewitt, Joseph Tauskela, Paul Morley, Trevor Atkinson, Jon P Durkin (2000) Transient NMDA Receptor Inactivation Provides Long-Term Protection to Cultured Cortical Neurons from a Variety of Death Signals, 7183-7192. 20 (19).

Download PDF (624.28 KB)

Graeme Hodgson, Nadia Agopyan, Claire-Anne Gutekunst, Blair R Leavitt, Fred LePiane, Roshni Singaraja, Desmond J Smith, Nagat Bissada, Krista McCutcheon, Jamal Nasir, Laure Jamot, Xiao-Jiang Li, Mary E Stevens, Erica Rosemond, John C Roder, Anthony G Phillips, Edward M Rubin, Steven M Hersch, Michael R Hayden, Molecular Medicine, British Columbia Vancouver, British Columbia, Toronto Toronto, Molecular Immunology, Medicine Atlanta, Human Genome Center Lawrence Berkeley Laboratories Berkeley, Disease Collaborative Research Group, The HD, Other YAC (1999) A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration, 181-192. In Neuron.

Download PDF (537 KB)

SHORT REVIEW (1999) Alzheimer’s Disease and the Amyloid ␤ Protein: What Is the Role of Amyloid?.

Download PDF (122.36 KB)

SHORT REVIEW (1999) Alzheimer’s Disease and the Amyloid ␤ Protein: What Is the Role of Amyloid?.

Download PDF (122.36 KB)

Ralph N Martins, CHIN WERN CHAN, EMMA WADDINGTON, GERALD VEURINK, SIMON LAWS, KEVIN CROFT, A M Dharmarajan (1999) And Oxidative Stress in the Pathogenesis of Alzheimer’s Disease, 367-392. In Human Biology.

Download PDF (122.8 KB)

Tsuneo Takadera, Ikumi Matsuda, Takao Ohyashiki (1999) Apoptotic Cell Death and Caspase-3 Activation Induced by N-Methyl-. In Methods.

Download PDF (309.69 KB)

Won-Ki Kim, Yun-Beom Choi, Posina V Rayudu, Prajnan Das, Wael Asaad, Derrick R Arnelle, Jonathan S Stamler, Stuart A Lipton, North Carolina, Results Endogenous N O S Activity Can Decrease NMDA Responses We, Endogenously Produced NO, Exogenous NO, Donors Decrease NMDA Receptor Responses Next, Sulfi- NO (1999) Attenuation of NMDA Receptor Activity and Neurotoxicity by Nitroxyl Anion, NO, 461-469. In October.

Download PDF (139.9 KB)

Lynda M Hawkins, Paul L Chazot, Anne Stephenson (1999) Biochemical Evidence for the Co-association of Three, 27211-27218. In Molecular Biology 274 (38).

Download PDF (298.88 KB)

Xingyu Chen, David Moore-Nichols, Hoanh Nguyen, ELIAS K MICHAELIS (1999) Calcium In ux Through NMDA Receptors, Chronic Receptor Inhibition by Ethanol and 2-Amino-5-Phosphonopentanoic Acid, and Receptor Protein Expression. In Cell.

Download PDF (208.36 KB)

Sic L Chan, Mark P Mattson (1999) Caspase and Calpain Substrates: Roles in Synaptic Plasticity and Cell Death, 167-190. In Journal of Neuroscience Research 190 (May).

Download PDF (294.19 KB)

National Academy, Proteolytic Processing, Physiological Regulation, Mabel Beckman Center (1999) Cellular mechanisms of ␤ -amyloid production and secretion, 11049-11053. 96 (September).

Download PDF (79.45 KB)

TERRE A SHARMA, I A N J REYNOLDS (1999) Characterization of the Effects of Polyamines on [ 125 I]MK-801 Binding to Recombinant, 1041-1047. In Pharmacology 289 (2).

Download PDF (114.04 KB)

Mark D Johnson, Yoshito Kinoshita, Hong Xiang, Saadi Ghatan, Richard S Morrison (1999) Contribution of p53-Dependent Caspase Activation to Neuronal Cell Death Declines with Neuronal Maturation, 2996-3006. In Journal of Neuroscience 19 (8).

Download PDF (831.55 KB)

Stephane Renard, Chantal Drouet-Petre, Michel Partiseti, Salomon Z Langer, David Graham (1999) Development of an inducible NMDA receptor stable cell line with an intracellular Ca, 319-328. In European Journal of Pharmacology.

Download PDF (388.91 KB)

Dieder Moechars, Ilse Dewachter, Kristin Lorent, Delphine Reverse, Veerle Baekelandt, Asha Naidu, Ina Tesseur, Kurt Spittaels, Chris Van Den Haute, Emile Godaux, Barbara Cordell, Fred Van Leuven (1999) Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain*, 6483-6492. In Molecular Biology 274 (10).

Download PDF (809.24 KB)

Margarita Behrens, Jaime Renart (1999) Expression of N-Methyl-D-Aspartate Receptors Using Vaccinia Virus Causes Excitotoxic Death in Human Kidney Cells, 135-144..

Download PDF (136.59 KB)

Nobuaki Yamada, Makoto Sudo, Haruo Okado, Masae Iino Akiko Miwa, Seiji Ozawa, Keisuke Tsuzuki (1999) Expression of recombinant NMDA receptors in hippocampal neurons by adenoviral-mediated gene transfer, 169-180. In Molecular Brain Research.

Download PDF (919.83 KB)

Douglas L Anders, Tana Blevins, GREG SUTTON, Sheridan Swope, JUDSON CHANDLER, John J Woodward (1999) Fyn Tyrosine Kinase Reduces the Ethanol Inhibition of Recombinant NR1/NR2A but Not NR1/NR2B NMDA Receptors Expressed in HEK 293 Cells.

Download PDF (123.31 KB)

Scott J Myers, Raymond Dingledine, Karin Borges (1999) Genetic regulation of glutamate receptor ion channels, 221-241. In Annu Rev Pharmacol.

Download PDF (205.15 KB)

Src Tyrosine Kinase, Ethanol Sensitivity, Recombinant NMDA Receptors Expressed (1999) Hek 293. In Direct 23 (2).

Download PDF (855.76 KB)

Qing Guo, Lois Sebastian, Bryce L Sopher, Miles W Miller, Carol B Ware, George M Martin, Mark P Mattson (1999) Increased Vulnerability of Hippocampal Neurons from Presenilin-1 Mutant Knock-In Mice to Amyloid ␤ -Peptide Toxicity: Central Roles of Superoxide Production and Caspase Activation.

Download PDF (383.86 KB)

Nature America Inc (1999) Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice, 101-106. In Nature Medicine.

Download PDF (211.58 KB)

Ricardo B Maccioni, Alejandra Alvarez, Rodrigo Toro, Alfredo Ca (1999) Inhibition of tau phosphorylating protein kinase cdk5 prevents L-amyloid-induced neuronal death ¨, 421-426. In Enzyme.

Download PDF (346.31 KB)

Susumu Tomita, Toshinori Ozaki, Hidenori Taru, Shinobu Oguchi, Shizu Takeda, Yoshimasa Yagi, Shigeru Sakiyama, Yutaka Kirino, Toshiharu Suzuki (1999) Interaction of a Neuron-specific Protein Containing PDZ Domains with Alzheimer’s Amyloid Precursor Protein*, 2243-2254. In Molecular Biology 274 (4).

Download PDF (680.04 KB)

Maria Sancha Santos, Catarina Oliveira (1999) Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by A␤ Peptides on PC12 Cells: Protection by Antioxidants, 209-219. In Neurobiology of Disease.

Download PDF (425.41 KB)

Akiyuki Takahashi, Patricia Camacho, James D Lechleiter, Brian Herman (1999) Measurement of Intracellular Calcium, 1089-1125. In October 79 (4).

Download PDF (724.89 KB)

G Parsons, W Danysz, G Quack (1999) Memantine is a clinically well tolerated, 735 - 767. In Pharmacological Research.

Download PDF (1.09 MB)

Paolo Calabresi, Diego Centonze, Antonio Pisani, Giorgio Bernardi (1999) Metabotropic Glutamate Receptors and Cell-Type-Speci c Vulnerability in the Striatum: Implication for Ischemia and Huntington’s Disease, 97-108. In Experimental Neurology.

Download PDF (178.38 KB)

CrmA INHIBITS APOPTOSIS INDUCED BY (1999) Multiple Pathways of Apoptosis in PC12 Cells, 2107-2112. In Molecular Biology 274 (4).

Download PDF (276 KB)

Nature America Inc (1999) News & views, 270-271. In NATURE MEDICINE 5 (3).

Download PDF (110.57 KB)

J Harte, S McCarthy, K Taylor, A Kinzig, M Fischer, M L Cody, R Ricklefs, D Schluter, W E Kunin, T Blackburn, I Hanski, J Kouki, A Halkka, Chicago Press, Ehlers K Munchen, Mellon Foundation, Endowed Chair (1999) NMDA Receptor–Mediated K ؉ Ef ux and Neuronal Apoptosis, 336-339. In Science 284 (April).

Download PDF (228.69 KB)

Aspartate Receptor Antagonist MK-, Radical Scavengers Protect Cholinergic Nucleus Basalis Neurons, Amyloid Neurotoxicity (1999) No title., 109-121. In Control.

Download PDF (301.08 KB)

Jordi Caldero, Joan Ribera, Olga Tarabal, Ronald W Oppenheim, Josep E Esquerda (1999) Opposing Effects of Excitatory Amino Acids on Chick Embryo Spinal Cord Motoneurons: Excitotoxic Degeneration or Prevention of Programmed Cell Death, 10803-10812. In Journal of Neuroscience 19 (24).

Download PDF (1.25 MB)

Roger F Castilho, Manus W Ward, David G Nicholls (1999) Oxidative Stress, Mitochondrial Function, and Acute Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells. In Statistics.

Download PDF (203.42 KB)

Roger A Nicoll (1999) Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models, 3228-3233. In Neurobiology 96 (March).

Download PDF (250.03 KB)

Dean M Hartley, Dominic M Walsh, Chianping P Ye, Thekla Diehl, Sara Vasquez, Peter M Vassilev, David B Teplow (1999) Proto brillar Intermediates of Amyloid ␤ -Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons, 8876-8884. In Baseline 19 (20).

Download PDF (1.04 MB)

Alan Collmer, Jorge L Badel, Amy O Charkowski, Wen-Ling Deng, Derrick E Fouts, Adela R Ramos, Amos H Rehm, Deborah M Anderson, Olaf Schneewind, James R Alfano (1999) Pseudomonas syringae Hrp type III secretion system and effector proteins. In PNAS.

Download PDF (247.72 KB)

SHORT REVIEW (1999) Regulation of Amyloid Precursor Protein Cleavage.

Download PDF (229 KB)

Akihiko Nunomura, George Perry, Miguel A Pappolla, Ramon Wade, Keisuke Hirai, Shigeru Chiba, Mark A Smith (1999) RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease, 1959-1964. In Journal of Neuroscience 19 (6).

Download PDF (499.8 KB)

Masanori Otsuka, Tokyo Medical, Masato Kasuga, Shigeaki Baba, Sunil J Wimalawansa, Texas Medical Branch, Ube Research Laboratory (1999) Selected references 1. In Science 20 (February).

Download PDF (139.16 KB)

Catriona A McLean, Robert A Cherny, Fiona W Fraser, Stephanie J Fuller, Margaret J Smith, Konrad Beyreuther, Ashley I Bush, Colin L Masters (1999) Soluble Pool of A␤ Amyloid as a Determinant of Severity of Neurodegeneration in Alzheimer’s Disease, 860-866. In Annals of Neurology.

Download PDF (458.48 KB)

Nansheng Chen, Tao Luo, Lynn A Raymond (1999) Subtype-Dependence of NMDA Receptor Channel Open Probability, 6844-6854. In Journal of Neuroscience 19 (16).

Download PDF (316 KB)

Nansheng Chen, Tao Luo, Cheryl Wellington, Martina Metzler, Krista McCutcheon, Michael R Hayden, Lynn A Raymond (1999) Subtype-Speci c Enhancement of NMDA Receptor Currents by Mutant Huntingtin.

Download PDF (210.51 KB)

External Mg, Internal Mg, C Internal, X Molecular, A Outer, B Narrow, A AMPA, B NMDA, C NMDA, D Kainate (1999) The Glutamate Receptor Ion Channels. In Pharmacology 51 (1).

Download PDF (2.41 MB)

Raymond Dingledine, Karin Borges, BOWIE DEREK, STEPHEN F. TRAYNELIS (1999) The Glutamate Receptor Ion Channels. In Pharmacological Reviews 51 (1).

Download PDF (2.41 MB)

EPIDEMIOLOGYCOSTS O F DEMENTIA Alzheimer, European Union (1999) The glutamatergic system and neurodegeneration in dementia: preventive strategies in alzheimer's disease, 3-47. In INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY 47 (June 1998).

Download PDF (851.27 KB)

Kenneth R Tovar, GARY L WESTBROOK (1999) The Incorporation of NMDA Receptors with a Distinct Subunit Composition at Nascent Hippocampal Synapses, 4180-4188. In Journal of Neuroscience 19 (10).

Download PDF (292.68 KB)

ROLE F O R INSULIN RECEPTOR SUBSTRATE-, T H E NEUROTROPHIC ACTION OF, ASPARTATEITS INHIBITION B Y ETHANOL (1998) -aspartate Inhibits Apoptosis through Activation of Phosphatidylinositol 3-Kinase in Cerebellar Granule Neurons, 26596 -26602. In Molecular Biology 273 (41).

Download PDF (267.15 KB)

Quan Chen, John W Olney, PETER D LUKASIEWICZ, TODD ALMLI, CARMELO ROMANO (1998) -Independent Excitotoxic Neurodegeneration in Isolated Retina, an Intact Neural Net: A Role for Cl, 564 -572. In MOLECULAR PHARMACOLOGY.

Download PDF (248.99 KB)

Donald L Price, Rudolph E Tanzi, David R Borchelt, Sangram S Sisodia (1998) ALZHEIMER’S DISEASE: Genetic Studies and Transgenic Models, 461-493. In Annu Rev Genet.

Download PDF (263.82 KB)

Eiharu Morikawa, Hisashi Mori, Yuji Kiyama, Masayoshi Mishina, Takao Asano, Takaaki Kirino (1998) Attenuation of Focal Ischemic Brain Injury in Mice De cient in the ⑀ 1 (NR2A) Subunit of NMDA Receptor, 9727-9732. In Image (Rochester, N.Y.) 18 (23).

Download PDF (288.39 KB)

Ernesto Carafoli, Maurizio Molinari (1998) BREAKTHROUGHS AND VIEWS Calpain: A Protease in Search of a Function?, 193-203. In Biochemical and Biophysical Research Communications 203 (247).

Download PDF (139.91 KB)

Xiaoning Bi, Yongqi Rong, Jing Chen, Sandeep Dang, Zhuo Wang, Michel Baudry (1998) Calpain-mediated regulation of NMDA receptor structure and function, 245-253. In Brain Research.

Download PDF (1.16 MB)

Kazuho Abe, Hiroshi Saito (1998) Cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes, 295 - 305. In Neuroscience research.

http://linkinghub.elsevier.com/retrie...

Download PDF (560.98 KB)

Zhihua Qiu, Dan D Sweeney, Jeffrey G Netzeband, Donna L Gruol (1998) Chronic Interleukin-6 Alters NMDA Receptor-Mediated Membrane Responses and Enhances Neurotoxicity in Developing CNS Neurons, 10445-10456. In Journal of Neuroscience 18 (24).

Download PDF (210.22 KB)

Konrad Beyreuther (1998) Clinical review. In System 316 (February).

Download PDF (483.51 KB)

STEPHEN F HEINEMANN (1998) Direct effects of metabotropic glutamate receptor compounds on native and recombinant, 8969-8974. In Neurobiology 95 (July).

Download PDF (270 KB)

Bodo Laube, Jochen Kuhse, Heinrich Betz (1998) Evidence for a Tetrameric Structure of Recombinant NMDA Receptors, 2954-2961. In Journal of Neuroscience 18 (8).

Download PDF (142 KB)

Stephen D Hess, Lorrie P Daggett, Charles Deal, Chin-Chun Lu, Edwin C Johnson (1998) Functional Characterization of Human N-Methyl-D-Aspartate Subtype 1A/2D Receptors. In Currents.

Download PDF (1 MB)

Vladimir A Tyurin, Yulia Tyurina, Peter J Quinn, Nina F Schor Raghavan Balachandran, Billy W Day, Valerian E Kagan (1998) Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection, 270-281. In Molecular Brain Research.

Download PDF (223.96 KB)

I Introduction, A Basic, B NR, C Distribution, D Glutamate, I Physiological, A Glycine, B Desensitization, C Endogenous, D Kynurenic, V Exogenous, A Agonists, B Partial, C Antagonists, D Implications, F Allosteric, I Therapeutic, A Pharmacokinetic, B Side (1998) Glycine and N-Methyl-. In Pharmacology 50 (4).

Download PDF (971.28 KB)

Tooraj Mirshahi, Douglas L Anders, Kimberly M Ronald, John J Woodward (1998) Intracellular Calcium Enhances the Ethanol Sensitivity of NMDA Receptors Through an Interaction with the CO Domain of the NR1 Subunit. In Cloning.

Download PDF (1.36 MB)

Samantha L Budd (1998) Mechanisms of Neuronal Damage in Brain Hypoxia/Ischemia: Focus on the Role of Mitochondrial Calcium Accumulation, 203-229. In Science 80 (2).

Download PDF (407.6 KB)

ELIAS K MICHAELIS (1998) Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. In Progress in Neurobiology 54 (97).

Download PDF (1.93 MB)

Brigitte Pettmann, Christopher E Henderson, Neuronal Cell Death (1998) Neuronal Cell Death Review, 633-647. In Cell.

Download PDF (276.77 KB)

Elfrida R Grant, Norifusa J Anegawa, David R Lynch (1998) Opposing Contributions of NR1 and NR2 to Protein Kinase C Modulation of NMDA Receptors.

Download PDF (1.29 MB)

RODNEY P GUTTMANN, Gail V W Johnson (1998) Oxidative Stress Inhibits Calpain Activity, 13331-13338. In Molecular Biology 273 (21).

Download PDF (274.97 KB)

Paul Desjardins, Stephane Ledoux, INTRODUCTION Apoptosis (1998) Review Article The Role of Apoptosis in Neurodegenerative Diseases. In Metabolic Brain Disease 13 (2).

Download PDF (1.73 MB)

Lalitha Tenneti, Carol M Troy, Stuart A Lipton (1998) Role of Caspases in N-Methyl-D-Aspartate-Induced Apoptosis in Cerebrocortical Neurons.

Download PDF (2.37 MB)

Roger Tsien (1998) The green fluorescent protein, 509-544. In Annu Rev Biochem.

Download PDF (562.69 KB)

Guido Kroemer, Bruno Dallaporta (1998) The mitochondrial death/life regulator in apoptosis and necrosis, 619-642. In Annu Rev Physiol.

Download PDF (237.46 KB)

Jerry W Lin, Michael Wyszynski, Raghavan Madhavan, Robert Sealock, Jai Up Kim, Morgan Sheng (1998) Yotiao, a Novel Protein of Neuromuscular Junction and Brain That Interacts with Speci c Splice Variants of NMDA Receptor Subunit NR1, 2017-2027. In Journal of Neuroscience 18 (6).

Download PDF (1000 KB)

(1998) [Frontiers in Bioscience 3, a47-51, June 17, 1998] THE ALZHEIMER'S PLAQUES, TANGLES AND MEMORY DEFICITS MAY HAVE A COMMON ORIGIN - PART III: ANIMAL MODEL Ming Chen, 47-51. In Medicine.

Download PDF (80.51 KB)

Elfrida R Grant, Brian J Bacskai, David E Pleasure, Dolan B Pritchett, Michael J Gallagher, Shelley J Kendrick, Larry J Kricka, David R Lynch (1997) -aspartate Receptors Expressed in a Nonneuronal Cell Line Mediate Subunit-specific Increases in Free Intracellular Calcium*, 647-656. In Molecular Biology 272 (1).

Download PDF (600.37 KB)

Ana Cristina Rego, Marja S Santos, Catarina R Oliveira (1997) Adeno sine Triphosphate Degradation Products After Oxidative Stress and Metabolic Dysfunction in Cultured Retinal Cells, 1228-1235.

Download PDF (788.55 KB)

John Hardy (1997) Amyloid, the presenilins and Alzheimer’s disease, 154-159. 2236 (Table 1).

Download PDF (489.87 KB)

Disease Review, Greg M Cole, Sally A Frautschy Geriatric Research Education, Clinical Center, Sepulveda Veterans Affairs Medical Center Depts (1997) Animal Models for Alzheimer’s Disease, 2-10. In Review.

Download PDF (59.63 KB)

Davide Ferrari, PAOLA CHIOZZI, SIMONETTA FALZONI, MONICA D A L SUSINO, GINETTA COLLO, Gary Buell, FRANCESCO D I VIRGILI (1997) ATP-mediated Cytotoxicity in Microglial Cells, 1295-1301. In Neuropharmacology 36 (9).

Download PDF (772.17 KB)

Review Article (1997) Caspases : the executioners of apoptosis, 1-16. In Most.

Download PDF (691.86 KB)

MARK Sanders-Brown P MATTSON, Research Center, Kmtucky I II, Precursor Protein Cellular Expression, P-Amyloid Precursor Proteins Proteolytic Processing, Amyloid Precursor Protein Functions, Precursor Protein, Neurons A Neurotrophic, Arnyloid Precursor Protein, Nonneuronal Cells Functional Domains, Secreted Forms (1997) Cellular Actions of &4myloid Precursor Protein and Its Soluble and Fibrillogenic Derivatives. In October 77 (4).

Download PDF (15.25 MB)

JUDSON CHANDLER, GREG SUTTON, DEAN NORWOOD, COLIN SUMNERS, FULTON T CREWS (1997) Chronic Ethanol Increases, 733-740. In MOLECULAR PHARMACOLOGY.

Download PDF (379.1 KB)

Tana Blevins, Tooraj Mirshahi, JUDSON CHANDLER, John J Woodward (1997) Effects of Acute and Chronic Ethanol Exposure on Heteromeric N-Methyl-D-Aspartate Receptors Expressed in HEK 293 Cells. In Cell.

Download PDF (1.1 MB)

Keiko Tominaga, Taichi Uetsuki, Akihiko Ogura, Kazuaki Yoshikawa (1997) Glutamate responsiveness enhanced in neurones expressing amyloid precursor protein, 2067-2072. In Science.

Download PDF (1.09 MB)

Shigeo Uchino, Yoshihisa Kudo, Wakako Watanabe, Sadayo Nakajima-Iijima, Masayoshi Mishina (1997) Inducible expression of N-methyl-, 1-11. In Molecular Brain Research.

Download PDF (1.03 MB)

Brief De (1997) Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis, 1481-1486. In Journal of Experimental Medicine 185 (8).

Download PDF (195.58 KB)

Bodo Laube, Hirokazu Hirai, Mike Sturgess, Heinrich Betz, Jochen Kuhse (1997) Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit, 493-503. In Cell.

Download PDF (361.61 KB)

Andreas Wenzel, Jean Marc Fritschy, Hanns Mohier, Dietmar Benke (1997) NMDA Receptor Heterogeneity During Postnatal Development of the Rat Brain: Differential Expression of the NR2A, NR2B, and NR2C Subunit Proteins..

Download PDF (1.2 MB)

Richard F Cowburn, Birgitta Wiehager, Ewa Trief, Mo Li-Li, Erik Sundstrom (1997) No title., 1437-1442. In Neurochemical Research 22 (12).

Download PDF (677.64 KB)

David J Laurie, Ilse Bartke, Ralf Schoepfer, Kurt Naujoks, Peter H Seeburg (1997) Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies. In Proteins.

Download PDF (447.37 KB)

T H E JOURNAL O F COMPARATIVE NEUROLOGY, Carlos Portera-Cailliau, Donald L Price, L E E J MARTIN (1997) The journal of comparative neurology 378:88–104 (1997), 88-104. In Laboratory Animals 104 (June 1996).

Download PDF (1.73 MB)

JIANHONG LUO, YUEHUA WANG, ROBERT P YASUDA, ANTHONE W DUNAH, Barry B Wolfe (1997) The Majority of, 79 -86. In J Neurosci.

Download PDF (432.2 KB)

The Type III, Secretion Pathway, Plant Pathogenic Bacteria, Avr Proteins (1997) The Type III (Hrp) Secretion Pathway of Plant Pathogenic Bacteria: Traf cking Harpins, Avr Proteins, and Death, 5655-5662. In Microbiology 179 (18).

Download PDF (229.67 KB)

Qljmpja Meucci, Tullio Florio, Morena Fattore, Mario Salmona, Gennaro Schettini (1996) /325—35 Alters Calcium Homeostasis and Induces Neurotoxicity in Cerebellar Granule Cells.

Download PDF (1.13 MB)

The Plant Cell, American Society, Plant Physiologists, Alan Collmer, Plant Pathology, New York, INTRODUCTION Higher, The Hr (1996) Bacterial Pathogens in Plants: Life up against the WalI, 1683-1698. In Plant Cell 8 (October).

Download PDF (1.98 MB)

Neurobiology Vol, Elsevier Science Ltd, Great Britain, Rochester Medical Center, Elmwood Avenue Box, Woodruff Memorial Building (1996) BIOENERGETICS AND GLUTAMATE EXCITOTOXICITY JAMES G. GREENE* and J. TIMOTHY GREENAMYREt:~. In Progress in Neurobiology.

Download PDF (2.21 MB)

Zhengui Xia, Henryk Dudek, Cindy K Miranti, Michael E Greenberg (1996) Calcium In ux via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism, 5425-5436. 16 (17).

Download PDF (880.57 KB)

Shelley J Kendrick, David R Lynch, Dolan B Pritchett (1996) Characterization of Glutamate Binding Sites in Receptors Assembled from Transfected NMDA Receptor Subunits.

Download PDF (1.02 MB)

A Wenzel, M Villa, H Mohler, D Benke (1996) Developmental and Regional Expression of NMDA Receptor Subtypes Containing the NR2D Subunit in Rat Brain. In DesIgn.

Download PDF (1.14 MB)

David G Standaert, Bernhard Landwehrmeyer, Julie A Kerner, John B Penney Jr, Anne B Young (1996) Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus, 89-102. In Magnesium.

Download PDF (1.06 MB)

Medical Sciences (1996) Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells, 2180-2185. In Sciences-New York 93 (March).

Download PDF (655 KB)

Glutamate Receptor Ion Channel Properties Predict Vulnerability, Transfected Nonneuronal Cell Line (1996) Glutamate Receptor Ion Channel Properties Predict Vulnerability to Cytotoxicity in a Transfected Nonneuronal Cell Line, 102-115. In Molecular and Cellular Neuroscience 115 (0008).

Download PDF (286.96 KB)

Glutamate Receptor Ion Channel Properties Predict Vulnerability, Transfected Nonneuronal Cell Line (1996) Glutamate Receptor Ion Channel Properties Predict Vulnerability to Cytotoxicity in a Transfected Nonneuronal Cell Line, 102-115. In Molecular and Cellular Neuroscience 115 (0008).

Download PDF (286.96 KB)

Graham M Gibb, Steven Jacobsen, Jean-Marc Gallo, Brian H Anderton (1996) In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase-3.,8. In Peptides.

Download PDF (1.03 MB)

Bruce A Yankner (1996) Mechanisms of Neuronal Degeneration in Alzheimer’s Disease, 921-932. In Cell.

Download PDF (160.05 KB)

Sarah Grimwood, Elizabeth Gilbert, Ian Ragan, Peter H Hutson (1996) Modulation of 45Ca2~Influx into Cells Stably Expressing Recombinant Human NMDA Receptors by Ligands Acting at Distinct Recognition Sites, 2589-2595.

Download PDF (916.99 KB)

L Price, J Martin (1996) N-Methyl-D-Aspartate Receptor Proteins NR2A and NR2B Are Differentially Distributed in the Developing Rat Central Nervous System as Revealed by Subunit-Specific Antibodies. In Laboratory Animals.

Download PDF (1.01 MB)

When NR (1996) NMDA receptors: from genes to channels. In Science 17 (October).

Download PDF (803.68 KB)

Brain Res, FEBS Lett, Brain Lett, Acknowledgements The, Wellcome Trust, Biological Sciences Research Council (1995) (1994) 1.. In REVIEW.

Download PDF (1.05 MB)

Brain Research, Wei-Dong Le, Luis V Colom, Wen-jie Xie, Glenn Smith, Maria Alexianu, Stanley H Appel (1995) Brain research, 49-60. In Brain Research.

Download PDF (1.17 MB)

Brain Research, Wei-Dong Le, Luis V Colom, Wen-jie Xie, Glenn Smith, Maria Alexianu, Stanley H Appel (1995) Brain research, 49-60. In Brain Research.

Download PDF (1.17 MB)

Nikolaus Deitcher, Schahram Akbarian, Carlin L Chi, Cynthia L Leclerc, Marc Awobuluyi, Michele K Wu, Joseph P Yuan, Edward G Jones, Stuart A Lipton (1995) Developmental and Regional Expression Pattern of a Novel NMDA Receptor-like Subunit (NMDAR-L) in the Rodent Brain. In Culture 75 (October).

Download PDF (3.44 MB)

KENNETH HENSLEY, ROBERT A LEEDLE, JOHN M CARNEY (1995) Direct Evidence of Oxidative Injury Produced by the Alzheimer’s p-Amyloid Peptide (I-40) in Cultured Hippocampal Neurons, 193-202. In Pathology 202 (46).

Download PDF (5.79 MB)

Molecular Psychiatry, Connecticut Mental Health Center, New Haven, Molecular Neurobiology Laboratory, La Jolla, San Diego (1995) Division of Molecular Psychiatry, Departments of ‘Pharmacology and 2Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven, Connecticut 06508, 3Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, Califo. In Journal of Neuroscience 15 (October).

Download PDF (3.54 MB)

Steven M Rothman, John W Olney, IwlifS NblfrosC (1995) Excitotoxicity and the NMDA receptor - still lethal after eight years, 7-8.

Download PDF (295.78 KB)

Jie Zhong, David P Carrozza, Keith Williams, Perry B Molinoff (1995) Expression of mRNAs Encoding Subunits of the NMDA Receptor in Developing Rat Brain. In Methods.

Download PDF (1.01 MB)

Tana Blevins, Tooraj Mirshahi, John J Woodward (1995) I[IIilS, 214-218. In Neuroscience Letters.

Download PDF (507.57 KB)

Brain Research (1995) Neurodegeneration mediated by glutamate and/3-amyloid peptide: a comparison and possible interaction, 169-179. In Exposure.

Download PDF (1.06 MB)

PERMEABILIZATION O F T H E INNER MITOCHONDRIAL, B Y Ca, IONS I S STIMULATED BY, BUTYL HYDROPEROXIDE, MEDIATED B Y REACTIVE OXYGEN SPECIES GENERATED B Y MITOCHONDRIA (1995) Original Contribution, 479-486. In Science 18 (3).

Download PDF (744.79 KB)

David R Lynch, Shelley Lenz, Norifusa J Anegawa, Marc Dichter (1995) Pharmacological Characterization of Heterodimeric NMDA Receptors Composed of NR la and 2B Subunits : Differences with Receptors Formed from NR 1 a and 2A. In Differences.

Download PDF (769.38 KB)

H Mori, M Mishina, The NMDA (1995) Review: Neurotransmitter Receptors VIII Structure and Function of the NMDA Channel, 1219-1237. In Science 34 (10).

Download PDF (2.18 MB)

TNF-Induced Liver Failure, Hepatocyte Apoptosis, Nitrite Release (1995) T 1994.. 1 (28).

Download PDF (3.13 MB)

Norifusa J Anegawa, David R Lynch, Todd A Verdoorn, Dolan B Pritchett (1995) Transfection of N-Methyl-D-Aspartate Receptors in a Nonneuronal Cell Line Leads to Cell Death. In Currents.

Download PDF (1.17 MB)

McBAINM. L MAYER, Molecular Neurophysiology, Child Health Development, National Institutes (1994) Acid Receptor Structure. In PHYSIOLOGICAL REVIEWS 74 (3).

Download PDF (11.14 MB)

Paul L Chazot, Miroslav Cik, Anne Stephenson, The N-methyla-aspartate, NMDA Rl (1994) Molecular Characterization of N-Methyl-D-aspartate Receptors Expressed in Mammalian Cells Yields Evidence. In Molecular Biology.

Download PDF (3.82 MB)

Takahiro Ishii, Koki Moriyoshi, Hidemitsu Sugihara, Kazuhiro Sakurada, Hiroshi Kadotani, Mineto Yokoi, Chihiro Akazawa, Ryuichi ShigemotoS, Noboru MizunoS, Masayuki Masu, Shigetada Nakanishie, The NMDA, Voltage-dependent Mg (1993) Molecular Characterization of the Family of the N-Methyl-D-Aspartate Receptor Subunits*, 2836-2843. In Molecular Biology 268 (4).

Download PDF (2.67 MB)

Douglas H Smith, Koichi Okiyama, Mark J Thomas, Tracy K McIntosh, Connecticut Health Center (1993) No title., 5383-5392. In Evaluation 13 (December).

Download PDF (1.31 MB)

R Sprengel, H Seeburg (1993) The unique properties of glutamate receptor channels, 90-94. In FEBS Letters 325 (1).

Download PDF (545.93 KB)

Mark P Mattson, Bin Cheng, Dave Davis, Karin Bryant, Ivan Lieberburg, Sanders-Brown Research Center, Athena Neurosciences, E Rydel (1992) P-Amyloid Peptides Destabilize Calcium Homeostasis Human Cortical Neurons Vulnerable to Excitotoxicity. In Journal of Neuroscience 12 (February).

Download PDF (2.51 MB)

H Nakamura, RA Nemenoff, JH Gronich (1991) Subcellular characteristics of phospholipase A2 activity in the rat kidney. Enhanced cytosolic, mitochondrial, and microsomal phospholipase A2 enzymatic activity after, 1810-1818. In Journal of Clinical 87 (May).

http://www.ncbi.nlm.nih.gov/pmc/artic...

Download PDF (1.94 MB)

Download PDF (1.19 MB)

Involved, Its Klllam, Hugh MeLcnnan, Vancouver, Important From, L T P Increased, InterestLTP. GLC, John Davies, PharmacyLondon (1990) Emories of NMDA receptors and LTP, 1-3.

Download PDF (414.44 KB)

North Torrey Pines Road, La Jolla, South Euclid Avenue (1990) Neurobiology of disease, 655-660. In Current Opinion in Neurobiology.

Download PDF (145.69 KB)

Dennis J Selkoe Amyloid ␤ -Protein and the Genetics of Alzheimer’s Disease*. In Molecular Biology.

Download PDF (83.87 KB)

H A I LIN, RAJINDER BHATIA, RATNESHWAR LAL, R Amyloid Amyloid ␤ protein forms ion channels: implications for Alzheimer’s disease pathophysiology, 2433-2444. In The FASEB Journal.

Download PDF (905 KB)

Hye-Sun Kim, Cheol Hyoung Park, SEOK H O CHA, JUN-HO LEE, Sangwon Lee, YANGMEE KIM, JONG-CHEOL RAH, SUNG-JIN JEONG, Yoo-Hun Suh Carboxyl-terminal fragment of Alzheimer’s APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity. In The FASEB Journal.

Download PDF (695.31 KB)

Stuart A Lipton Clinically tolerated NMDA receptor antagonists and newly cloned NMDA receptor subunits that mimic them, 72-78. In Europe.

Download PDF (223 KB)

URSULA RAUEN, BERNHARD POLZAR, HARALD STEPHAN, HANS GEORG MANNHERZ, HERBERT D E GROOT Cold-induced apoptosis in cultured hepatocytes and liver endothelial cells: mediation by reactive oxygen species, 155-168. In The FASEB Journal.

Download PDF (854 KB)

Supplemental Data, Myung Jong Kim, ANTHONE W DUNAH, Yu Tian Wang, Morgan Sheng Supplemental Experimental Procedures Total Endogenous GluR, Staining Total, Intracellular Staining, T-GluR Cultured, Triton X-, Endogenous PSD, Staining For PSD, NMDA-Induced GluR, Internalization Surface GluR, Oncogene Science Differential Roles of NR2A- and NR2B-Containing NMDA Receptors in Ras-ERK Signaling and AMPA Receptor Trafficking, 1-8.

Download PDF (5.46 MB)

Recent Mechanistic, Molecular Concepts Drug-induced Apoptotic Neurodegeneration in the Developing Brain. In Brain.

Download PDF (431.33 KB)

Jason T Huse, Damani Byant, Yaxiong Yang, Donald S Pijak, Robert W Doms, David G Cook, Neurodegenerative Disease Research, Geriatric Research Education, Clinical Center, Seattle Wa Endoproteolysis of E-secretase (BACE) within its catalytic domain: A potential mechanism for regulation..

Download PDF (1.39 MB)

YINWEN JUDY ZHU, H A I LIN, RATNESHWAR LAL Fresh and non brillar amyloid ␤ protein(1– 40) induces rapid cellular degeneration in aged human broblasts: evidence for A␤P-channel-mediated cellular toxicity. In The FASEB Journal.

Download PDF (687.72 KB)

Sarah Grimwood, Beatrice Le Bourdell, John R Atack, Cheryl Barton, Wendy Cockett, Susan M Cook, Elizabeth Gilbert, Peter H Hutson, Ruth M McKernan, Jan Myers, Ian Ragan, Peter B Wingrove, Paul J Whiting Generation and Characterisation of Stable Cell Lines Expressing Recombinant Human N-Methyl-D-Aspartate Receptor Subtypes, 2239-2247. In Test.

Download PDF (1.24 MB)

C K ELISABETH HANSSON, Lars Ro Glial neuronal signaling in the central nervous system ¨, 341-348. In The FASEB Journal.

Download PDF (341 KB)

Molecular Classi, Ionotropic Receptors Glutamate Neurotransmission: Characteristics of NMDA Receptors in the Mammalian Brain. In In vivo.

Download PDF (156 KB)

STIMULATED SECRETION O F AMYLOID PRECURSOR PROTEIN FROM CORTICAL R A T BRAIN SLICES Glutamate!stimulated secretion of amyloid precursor protein from cortical rat brain slices. In Science.

Download PDF (295.04 KB)

Increased Vulnerability, Brain Mitochondria, Rats With Aging Increased Vulnerability of Brain Mitochondria in Diabetic (Goto-Kakizaki) Rats With Aging and Amyloid-␤ Exposure, 1449-1456. In Diabetes.

Download PDF (284.65 KB)

D N A Ladder Invitrogen ™ Nucleic Acid Markers, 9-10. In Business.

Download PDF (120.01 KB)

KIMMO HATANP Neuronal Dysfunction in Aging and Alzheimer’s Disease.

Download PDF (876.84 KB)

STEPHEN D SKAPER, LAURA FACCI, PAUL J L M STRIJBOS Neuronal Protein Kinase Signaling Cascades and Excitotoxic Cell Death, 11-22. In Sciences.

Download PDF (714.1 KB)

Biological Sciences, Cell Biology, Sick Children, Canada Correspondence, Elsevier Science Ltd NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity, 336-342. In Current Opinion in Neurobiology.

Download PDF (151.32 KB)

No title..

Download PDF (7.13 MB)

No title..

Download PDF (359.25 KB)

No title..

Download PDF (1.56 MB)

No title..

Download PDF (1.23 MB)

No title..

Download PDF (2.72 MB)

No title...

Download PDF (300.84 KB)

No title..

Download PDF (1.15 MB)

No title.. In Physics.

Download PDF (2.92 MB)

No title..

Download PDF (2.08 MB)

FLINT Neurochemistry Massachusetts, U S A Neurology Service, Massachusetts General Hospital Of excitotoxicity. In The FASEB Journal.

Download PDF (1.61 MB)

Programmed Cell Death Richard A. Lockshin. In Stroke.

Download PDF (3.24 MB)

NMDA Receptors Sigma, PCP, and NMDA Receptors. In Medicus.

Download PDF (1.93 MB)

Some History Electrical Properties, Membranes Basics, Voltage Clamp Ion Channels Some History Electrical Properties of Membranes Basics of Voltage Clamp Ion Channels. In Mosaic.

Download PDF (1.88 MB)

Supplementary Online Materials Materials and methods Materials:, 1-8. In J Physiol (Lond).

Download PDF (160.43 KB)

Denmark Hill Campus, Bessemer Road, London SE, Cell Physiology, Leicester LE, Gower Street, London WC, Elsevier Science Ltd Synaptic P2X receptors, 378-386. In Current Opinion in Neurobiology.

Download PDF (704.68 KB)

Technical assistance. In Elements.

Download PDF (521 KB)

Newton Court, Elsevier Science Ltd, Semliki Forest Techniques for gene transfer into neurons, 566-573. In J Neurosci.

Download PDF (110.97 KB)

Disease Research The cell biology of Alzheimer’s disease: uncovering the secrets of secretases, 585-590. In Current Opinion in Neurobiology.

Download PDF (191.65 KB)

No title..

Download PDF (1.14 MB)

António Domingues's Publications

Journal Article