David Briggs, PhD Protein Crystallography
Manchester, United Kingdom
Research field: Biological Sciences - Biophysics
Proteoglycans, Structural Biology, Interaction analysis, Crystallography, SAXS
Publications
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Journal Article (10)
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Batiste Boëda, Phillip P Knowles, David C Briggs et al. (2011) Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A., 11543-54. In The Journal of biological chemistry 286 (13).Download PDF (4.76 MB)
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David C Briggs, Claire E Naylor, James G Smedley et al. (2011) Structure of the food-poisoning Clostridium perfringens enterotoxin reveals similarity to the aerolysin-like pore-forming toxins., 138-49. In Journal of molecular biology 413 (1).
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Natalia S Baranova, Erik Nilebäck, F Michael Haller et al. (2011) The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers, 25675-25686. In The Journal of biological chemistry 286 (29).http://www.jbc.org/content/286/29/256...
papers://626fef3a-d60d-49b2-89f3-1999...
http://www.ncbi.nlm.nih.gov/pubmed/21...
Download PDF (2.87 MB)Download PDF (2.89 MB) -
David C Briggs, James G Smedley, Bruce a McClane et al. (2010) Crystallization and preliminary crystallographic analysis of the Clostridium perfringens enterotoxin., 794-7. In Acta crystallographica. Section F, Structural biology and crystallization communications 66 (Pt 7).Download PDF (292.73 KB)
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Antonio Inforzato, Clair Baldock, Thomas a Jowitt et al. (2010) The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2, 17681-17692. In The Journal of biological chemistry 285 (23).http://www.jbc.org/content/285/23/176...
papers://626fef3a-d60d-49b2-89f3-1999...
http://www.pubmedcentral.nih.gov/arti...
Download PDF (3.57 MB)Download PDF (3.57 MB) -
D Briggs, A Day (2008) A bug in CUB's clothing: similarity between clostridial CBMs and complement CUBs, 407-408. In Trends in Microbiology 16 (9).Download PDF (689.99 KB)
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G Fox, M Shafiq, D Briggs et al. (2007) Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases, 487-492. In Nature 447 (7143).Download PDF (657.78 KB)
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Batiste Boëda, David C Briggs, Theresa Higgins et al. (2007) Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding., 1071-82. In Molecular cell 28 (6).
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A M Al-Shangiti, C E Naylor, S P Nair et al. (2004) Structural relationships and cellular tropism of staphylococcal superantigen-like proteins, 4261-4270. In Infection and Immunity 72 (7).Download PDF (1013.78 KB)
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Graeme C. Clark, David C. Briggs, Tadahiro Karasawa et al. (2003) Clostridium absonum α-Toxin: New Insights into Clostridial Phospholipase C Substrate Binding and Specificity, 759-769. In Journal of Molecular Biology 333 (4).
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CV
Professional Experience
2006 - Present
Post Doc at Faculty of Life Sciences, University of Manchester
Manchester, United Kingdom
Manchester, United Kingdom
Apr 2004 - Oct 2006
Post Doc at Cancer Research UK, London Research Institute
London, United Kingdom
London, United Kingdom
Education
Sep 2001 - Apr 2004
Birkbeck College, University of London
in London, United Kingdom
PhD Protein Crystallography
PhD Protein Crystallography
Sep 2000 - Sep 2001
Birkbeck College, University of London
in London, United Kingdom
MRes Structural Biology
MRes Structural Biology
Sep 1996 - Jun 2000
University of Birmingham
in Birmingham, United Kingdom
BSc Biochemistry and Biotechnology
BSc Biochemistry and Biotechnology
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