Jason Hoyt, PhD
Vice-President, R&D and Chief Scientist, Mendeley Ltd.London, United Kingdom
Research field: Biological Sciences - Genetics
Gene therapy, Information technology, Biomedical informatics
Publications
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Book Section (4)
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Jason J Hoyt, Annahita Keravala, Jennifer Duda et al. (2008) Application of phiC31 for Gene Therapy in Mouse Hematopoietic Stem Cells. In Dissertation: Application and engineering of phage integrases for gene therapy 275 (2).Download PDF (1 MB)
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Jason J Hoyt, Christopher L Chavez (2008) Directed Evolution of phiC31 Integrase Toward a Single Location at Human Chromosome Xq22.1. In Dissertation: Application and engineering of phage integrases for gene therapy 275 (2).Download PDF (785.36 KB)
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Jason J Hoyt (2008) Dissertation Introduction, 1-15. In Dissertation: Application and engineering of phage integrases for gene therapy.Download PDF (133.31 KB)
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Jason J Hoyt, J Portlock, Michele P Calos (2008) Engineering of Hybrid phiC31-Zinc Finger Integrases with Altered Site-Specificity. In Dissertation: Application and engineering of phage integrases for gene therapy 275 (2).Download PDF (1.69 MB)
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Conference Proceedings (1)
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Jason J Hoyt, Jan Reichelt, Victor Henning (2009) Building successful online research networks with the Last.fm model, 103-114. In Proceedings of the 5th Open Knowledge Conference.
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Journal Article (2)
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Kris Jack, James Hammerton, Dan Harvey et al. (2010) Mendeley's Reply to the DataTEL Challenge, 1-3. In Procedia Computer Science 1 (2).Download PDF (13.42 KB)
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Annahita Keravala, Amy C Groth, Sohail Jarrahian et al. (2006) A Diversity of Serine Phage Integrases Mediate Site-Specific Recombination in Mammalian Cells. In Molecular Genetics and Genomics 275 (2).Download PDF (971.95 KB)
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Biographical Information
Jason Hoyt is Vice-President, Research & Development and Chief Scientist at Mendeley. He holds a PhD in Genetics from Stanford University where he was awarded the Ruth L. Kirschstein NIH predoctoral fellowship from 2002-2007.
He is involved at the executive level in all business and technical strategies at Mendeley. He established and oversees the API, search, statistics, and recommendation platforms. Additionally, he and the data mining team are responsible for content acquisition, content cleaning, and deduplicating more than 100 million documents to create the world's largest crowdsourced academic database. He has been awarded several major UK and European grants to investigate new data mining techniques and establish a pilot program with the University of Cambridge to integrate Mendeley with institutional repositories.
Unlike many knowledge gatekeepers in the academic publishing industry, he seeks to make science more transparent and collaborative. To advance science, knowledge needs to be easily accesible and reusable. Each of Mendeley's services and products adhere to this personal objective.
While at Stanford and prior to Mendeley, Jason saw the need for improved collaborative research through modern Internet technologies. This resulted in founding Ologeez, a peer-review literature search, recommendation engine and group collaboration for academics and industry professionals. It has been featured on TechCrunch and recognized world-wide by academics as one of the first attempts at "Research 2.0."
Also at Stanford he worked under Michele Calos researching human gene therapy. He developed new methods for non-viral gene delivery into mouse hematopoietic cells using the phiC31 integrase. Additionally, he used directed evolution to evolve phiC31, such that integration would occur at single, defined locations in the human genome, thus reducing potential side-effects. Also amongst his direct research advisors at Stanford were Gavin Sherlock, Anne Brunet, and Andrew Fire: 2006 Nobel Laureate in Medicine or Physiology.
His first programming experience: Circa 1981 at the age of five with his family's Atari 800 packing a whopping 8KB of memory and the BASIC language.
In his free time you’ll probably catch him at a small indie rock venue, daydreaming about a rock-and-roll life.
He is involved at the executive level in all business and technical strategies at Mendeley. He established and oversees the API, search, statistics, and recommendation platforms. Additionally, he and the data mining team are responsible for content acquisition, content cleaning, and deduplicating more than 100 million documents to create the world's largest crowdsourced academic database. He has been awarded several major UK and European grants to investigate new data mining techniques and establish a pilot program with the University of Cambridge to integrate Mendeley with institutional repositories.
Unlike many knowledge gatekeepers in the academic publishing industry, he seeks to make science more transparent and collaborative. To advance science, knowledge needs to be easily accesible and reusable. Each of Mendeley's services and products adhere to this personal objective.
While at Stanford and prior to Mendeley, Jason saw the need for improved collaborative research through modern Internet technologies. This resulted in founding Ologeez, a peer-review literature search, recommendation engine and group collaboration for academics and industry professionals. It has been featured on TechCrunch and recognized world-wide by academics as one of the first attempts at "Research 2.0."
Also at Stanford he worked under Michele Calos researching human gene therapy. He developed new methods for non-viral gene delivery into mouse hematopoietic cells using the phiC31 integrase. Additionally, he used directed evolution to evolve phiC31, such that integration would occur at single, defined locations in the human genome, thus reducing potential side-effects. Also amongst his direct research advisors at Stanford were Gavin Sherlock, Anne Brunet, and Andrew Fire: 2006 Nobel Laureate in Medicine or Physiology.
His first programming experience: Circa 1981 at the age of five with his family's Atari 800 packing a whopping 8KB of memory and the BASIC language.
In his free time you’ll probably catch him at a small indie rock venue, daydreaming about a rock-and-roll life.
CV
Professional Experience
2009 - Present
Vice-President, R&D and Chief Scientist at Mendeley Ltd.
London, United Kingdom
London, United Kingdom
Jan 2009 - Apr 2009
Oct 2006 - Apr 2009
Education
Sep 2002 - Sep 2008
Aug 1995 - Apr 2002
Brigham Young University
B.S. Microbiology, Chemistry, Business
B.S. Microbiology, Chemistry, Business
Sep 1991 - Jun 1995
San Ramon Valley High School
in Danville, California, United States
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