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Kiichi Hirota, MD, PhD's Publications

Kyōto, Japan

Research field: Biological Sciences
hypoxia
hypoxia-inducible factor
麻酔もやってます
Book Section (6) | Journal Article (99)

Journal Article

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Hiroshi Harada, Masahiro Inoue, Satoshi Itasaka, Kiichi Hirota, Akiyo Morinibu, Kazumi Shinomiya, Lihua Zeng, Guangfei Ou, Yuxi Zhu, Michio Yoshimura, W Gillies McKenna, Ruth J Muschel, Masahiro Hiraoka (2012) Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels, 783. In Nature communications.
Yasunobu Kawano, Masahiko Kawaguchi, Kiichi Hirota, Shinichi Kai, Noboru Konishi, Hitoshi Furuya (2012) Effects of n-propyl gallate on neuronal survival after forebrain ischemia in rats, 249-252. In Resuscitation 83 (2).
Shinichi Kai, Tomoharu Tanaka, Hiroki Daijo, Hiroshi Harada, Shun Kishimoto, Kengo Suzuki, Satoshi Takabuchi, Keizo Takenaga, Kazuhiko Fukuda, Kiichi Hirota (2012) Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner., 203-16. In Antioxidants & redox signaling 16 (3).
Y. Zuo, T. Zhao, S. Itasaka, L. Zeng, CJ. Yoem, K. Hirota, K. Suzuki, A. Morinibu, K. Shinomiya, G. Ou, M. Yoshimura, M. Hiraoka, H. Harada (2012) Involvement of decreased hypoxia-inducible factor 1 activity and resultant G1-S cell cycle transition in radioresistance of perinecrotic tumor cells. In Oncogene.
Tetsuya Kadonosono, Takahiro Kuchimaru, Shuichi Yamada, Yumi Takahashi, Atsushi Murakami, Taeko Tani, Hitomi Watanabe, Tomoharu Tanaka, Kiichi Hirota, Masahiro Inoue, Tetsuya Tsukamoto, Takeshi Toyoda, Koji Urano, Kazuhiko Machida, Tomoo Eto, Tomoyuki Ogura, Hideki Tsutsumi, Mamoru Ito, Masahiro Hiraoka, Gen Kondoh, Shinae Kizaka-Kondoh (2011) Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging., e26640. In PloS one 6 (11).
Hirota K, Segawa H, Fukuda K. Kishimoto S (2011) Ectopic ACTH syndrome revealed as severe hypokalemia and persistent hypertension during the perioperative period: a case report., 104-107. In J Anesth. 25 (1).
Hiroki Daijo, Shinichi Kai, Tomoharu Tanaka, Takuhiko Wakamatsu, Shun Kishimoto, Kengo Suzuki, Hiroshi Harada, Satoshi Takabuchi, Takehiko Adachi, Kazuhiko Fukuda, Kiichi Hirota (2011) Fentanyl activates hypoxia-inducible factor 1 in neuronal SH-SY5Y cells and mice under non-hypoxic conditions in a μ-opioid receptor-dependent manner., 144-52. In European journal of pharmacology 667 (1-3).
Tomoharu Tanaka, Shinichi Kai, Tomohiro Koyama, Hiroki Daijo, Takehiko Adachi, Kazuhiko Fukuda, Kiichi Hirota (2011) General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain, e29378. In PLoS ONE 6 (12).
広田　喜一 (2011) 周術期医学としてのハイポキシア生物学の探究, S183-S188. In 麻酔.
広田　喜一, 大条　鉱樹, 甲斐　慎一, 鈴木　堅悟, 岸本　俊, 松山　智紀 (2011) 炎症の制御点としての低酸素誘導性因子, S69-74. In 麻酔.
H Shinohara, K Hirota, M Sato, M Kakuyama, K Fukuda (2010) Monitored anesthesia care with dexmedetomidine of a patient with severe pulmonary arterial hypertension for inguinal hernioplasty. In J Anesth.
T Tanaka, T Wakamatsu, H Daijo, S Oda, S Kai, T Adachi, S Kizaka-Kondoh, K Fukuda, K Hirota (2010) Persisting mild hypothermia suppresses hypoxia-inducible factor 1{alpha} protein synthesis and HIF-1-mediated gene expression, R661-71. In Am J Physiol Regul Integr Comp Physiol.
T Koga, M Miyao, M Sato, K Hirota, M Kakuyama, H Tanabe, K Fukuda (2010) Pituitary apoplexy during general anesthesia in beach chair position for shoulder joint arthroplasty, 476-478. In J Anesth 24 (3).
T Tanaka, S Takabuchi, K Nishi, S Oda, T Wakamatsu, H Daijo, K Fukuda, K Hirota (2010) The intravenous anesthetic propofol inhibits lipopolysaccharide-induced hypoxia-inducible factor 1 activation and suppresses the glucose metabolism in macrophages, 54-60. In J Anesth 24 (1).
Yusuke Hara, Kiichi Hirota, Kazuhiko Fukuda (2009) Successful airway management with use of a laryngeal mask airway in a patient with CHARGE syndrome., 630-2. In Journal of anesthesia 23 (4).
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S Oda, T Oda, S Takabuchi, K Nishi, T Wakamatsu, T Tanaka, T Adachi, K Fukuda, R Nohara, K Hirota (2009) The calcium channel blocker cilnidipine selectively suppresses hypoxia-inducible factor 1 activity in vascular cells, 130-136. In Eur J Pharmacol.
T Wakamatsu, T Tanaka, S Oda, K Nishi, H Harada, H Daijo, S Takabuchi, S Kai, K Fukuda, K Hirota (2009) The intravenous anesthetics barbiturates inhibit hypoxia-inducible factor 1 activation, 17-22. In Eur J Pharmacol.
尾田　聖子, 広田　喜一, 高淵　聡史, 西　憲一郎, 若松　拓彦, 田中　具治, 福田　和彦 (2009) カルシウム拮抗薬cilnidipineは低酸素誘導性因子1の活性を血管由来細胞特異的に抑制する, 53-57. In Pharmacoanesthesiology.
広田　喜一 (2009) ハイポキシア生物学と周術期医学, 1911-1919. In 臨床麻酔.
広田　喜一, 若松　拓彦, 田中　具治, 大条　鉱樹, 甲斐　慎一 (2009) ハイポキシア生物学ー酸素代謝から見る生命現象ー, S138-S146. In 麻酔.
K Nishi, T Oda, S Takabuchi, S Oda, K Fukuda, T Adachi, G L Semenza, K Shingu, K Hirota (2008) LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent manner, 983-996. In Antioxid Redox Signal 10 (5).
S Oda, T Oda, K Nishi, S Takabuchi, T Wakamatsu, T Tanaka, T Adachi, K Fukuda, G L Semenza, K Hirota (2008) Macrophage migration inhibitory factor activates hypoxia-inducible factor in a p53-dependent manner, e2215. In PLoS ONE 3 (5).
M Kimura, S Takabuchi, T Tanaka, M Murata, K Nishi, S Oda, T Oda, M Kanai, K Fukuda, S Kizaka-Kondoh, T Adachi, A Takabayashi, G L Semenza, K Hirota (2008) N-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems, 97-105. In Biochem J 411 (1).
広田　喜一 (2008) ハイポキシア生物学-酸素代謝からみる生命現象の方程式. In 医学のあゆみ 225 (13).
広田　喜一, 田中　具治 (2008) 低酸素応答と低酸素センサー, 238-243. In Life Support and Anesthesia 15 (3).
T Umegaki, O Kikuchi, K Hirota, T Adachi (2007) Comparison of continuous intraarterial blood gas analysis and transcutaneous monitoring to measure oxygen partial pressure during one-lung ventilation, 110-111. In J Anesth 21 (1).
T Adachi, K Hirota, T Hara, Y Sasaki, Y Hara (2007) Exhaled carbon monoxide levels change in relation to inspired oxygen fraction during general anesthesia, 696-699. In Anesth Analg 105 (3).
T Hiraga, S Kizaka-Kondoh, K Hirota, M Hiraoka, T Yoneda (2007) Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer, 4157-4163. In Cancer Res 67 (9).
X Li, H Kimura, K Hirota, H Sugimoto, N Kimura, N Takahashi, H Fujii, H Yoshida (2007) Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-gamma in human proximal renal tubular cells, 1041-1051. In Nephrol Dial Transplant 22 (4).
P Sommani, K Yamashita, T Miyoshi, H Tsunemine, T Kodaki, H Mori, K Hirota, T Arai, M Sasada, K Makino (2007) Inhibitory Effect of 6-Formylpterin on HIF-1alpha Protein Accumulation, 2181-2184. In Biol Pharm Bull 30 (11).
広田　喜一 (2007) 細胞の低酸素応答機構-低酸素センサーを巡る論争, 2120-2126. In 実験医学.
T Oda, K Hirota, K Nishi, S Takabuchi, S Oda, H Yamada, T Arai, K Fukuda, T Kita, T Adachi, G L Semenza, R Nohara (2006) Activation of hypoxia-inducible factor 1 during macrophage differentiation, C104-C113. In Am J Physiol Cell Physiol.
F Tsukiyama, Y Nakai, M Yoshida, T Tokuhara, K Hirota, A Sakai, H Hayashi, T Katsumata (2006) Gallate, the component of HIF-inducing catechins, inhibits HIF prolyl hydroxylase, 234-239. In Biochem Biophys Res Commun 351 (1).
K Hirota, G L Semenza (2006) Regulation of angiogenesis by hypoxia-inducible factor 1, 15-26. In Crit Rev Oncol Hematol 59 (1).
広田喜一 (2006) 低酸素センサー-細胞は低酸素をいかに関知するか-, 11-15. In Anesthesia Network 10 (1).
X Li, H Kimura, K Hirota, H Sugimoto, H Yoshida (2005) Hypoxia reduces constitutive and TNF-alpha-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells, 1026-1034. In Biochem Biophys Res Commun 335 (4).
Taizo Hisano, Tsunehisa Namba, Mitsuko Hashiguchi-Ikeda, Tatsuya Ito, Kiichi Hirota, Kazuhiko Fukuda (2005) Inhibition of E-selectin-mediated leukocyte adhesion by volatile anesthetics in a static condition., 1-6. In Journal of anesthesia 19 (1).
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S Takabuchi, K Hirota, S Oda, K Nishi, T Oda, K Shingu, T Adachi, K Fukuda (2005) Opioid receptor stimulation does not affect cellular hypoxia-induced gene responses mediated by hypoxia-inducible factor 1 in cultured cell lines, 263-265. In J Anesth.
Kiichi Hirota, Gregg L Semenza (2005) Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases., 610-6. In Biochemical and biophysical research communications 338 (1).
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X Li, H Kimura, K Hirota, K Kasuno, K Torii, T Okada, H Kurooka, Y Yokota, H Yoshida (2005) Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells., 569-583. In Kidney Int..
Kenichiro Nishi, Kiichi Hirota, Satoshi Takabuchi, Seiko Oda, Kazuhiko Fukuda, Takehiko Adachi, Koh Shingu (2005) The effects of local anesthetics on cellular hypoxia-induced gene responses mediated by hypoxia-inducible factor 1., 54-9. In Journal of anesthesia 19 (1).
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K Hirota, T Hara, S Hosoi, Y Sasaki, Y Hara, T Adachi (2005) Two cases of hyperkalemia after administration of hypertonic mannitol during craniotomy, 75-77. In J. Anesth..
季　軒, 木村　秀樹, 広田　喜一, 糟野　健司, 淀井　淳司, 吉田　治義 (2005) 腎間質線維化における低酸素と炎症性サイトカインの関与-特にPAI-1, TIMP-1動態の検討-, 97-99. In Pharma Medica.
K Hirota, R Fukuda, S Takabuchi, S Kizaka-Kondoh, T Adachi, K Fukuda, G L Semenza (2004) Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling, 41521-41528. In J. Biol. Chem..
Kenji Kasuno, Satoshi Takabuchi, Kazuhiko Fukuda, Shinae Kizaka-Kondoh, Junji Yodoi, Takehiko Adachi, Gregg L Semenza, Kiichi Hirota (2004) Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling., 2550-8. In The Journal of biological chemistry 279 (4).
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Y Guo, L Einhorn, M Kelley, K Hirota, J Yodoi, R Reinbold, H Scholer, H Ramsey, R Hromas (2004) Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin, 259-264. In Stem Cells.
S Takabuchi, K Hirota, K Nishi, S Oda, T Oda, T Shingu, A Takabayashi, T Adachi, G L Semenza, K Fukuda (2004) The inhibitory effect of sodium nitroprusside on HIF-1 activation is not dependent on nitric oxide- soluble guanylyl cyclase pathway, 417-423. In Biochem. Biophys. Res. Commun..
Satoshi Takabuchi, Kiichi Hirota, Kenichiro Nishi, Seiko Oda, Tomoyuki Oda, Koh Shingu, Arimichi Takabayashi, Takehiko Adachi, Gregg L Semenza, Kazuhiko Fukuda (2004) The intravenous anesthetic propofol inhibits hypoxia-inducible factor 1 activity in an oxygen tension-dependent manner., 434-8. In FEBS letters 577 (3).
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T Itoh, K Hirota, T Hisano, T Namba, K Fukuda (2004) The volatile anesthetics halothane and isoflurane differentially modulate proinflammatory cytokine-induced p38 mitogen-activated protein kinase activation, 203-209. In J Anesth 18 (3).
広田喜一 (2004) 低酸素応答の分子機構, 34-38. In Anesthesia 21 Century.
Brian D Kelly, Sean F Hackett, Kiichi Hirota, Yuji Oshima, Zheqing Cai, Shannon Berg-Dixon, Ashley Rowan, Zhijiang Yan, Peter a Campochiaro, Gregg L Semenza (2003) Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1., 1074-81. In Circulation research 93 (11).
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S O Ang, H Chen, K Hirota, V R Gordeuk, J Jelinek, Y Guan, E Liu, A I Sergueeva, G Y Miasnikova, D Mole, P H Maxwell, D W Stockton, G L Semenza, J T Prchal (2002) Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia, 614-621. In Nat Genet 32 (4).
K Hirota (2002) Hypoxia-inducible factor 1, a master transcription factor of cellular hypoxic gene expression, 150-159. In J Anesth 16 (2).
Ryo Fukuda, Kiichi Hirota, Fan Fan, Young Do Jung, Lee M Ellis, Gregg L Semenza (2002) Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells., 38205-11. In The Journal of biological chemistry 277 (41).
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Y Matsuo, K Hirota, H Nakamura, J Yodoi (2002) Redox regulation by thioredoxin and its related molecules, 575-580. In Drug News & Perspective.
Shervin Karimpour, Junyang Lou, Lilie L Lin, Luis M Rene, Lucio Lagunas, Xinrong Ma, Sreenivasu Karra, C Matthew Bradbury, Stephanie Markovina, Prabhat C Goswami, Douglas R Spitz, Kiichi Hirota, Dhananjaya V Kalvakolanu, Junji Yodoi, David Gius (2002) Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation., 6317-27. In Oncogene 21 (41).
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Kiichi Hirota, Hajime Nakamura, Hiroshi Masutani, Junji Yodoi (2002) Thioredoxin superfamily and thioredoxin-inducing agents., 189-99. In Annals of the New York Academy of Sciences.
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T Arai, N Endo, K Yamashita, M Sasada, H Mori, H Ishii, K Hirota, K Makino, K Fukuda (2001) 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation, 248-259. In Free Radic Biol Med 30 (3).
K Hirota, M Murata, T Itoh, J Yodoi, K Fukuda (2001) An endogenous redox molecule, thioredoxin, regulates transactivation of epidermal growth factor receptor and activation of NF-kappaB by lysophosphatidic acid, 134-138. In FEBS Lett 489 (2-3).
P C Mahon, K Hirota, G L Semenza (2001) FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity, 2675-2686. In Genes Dev 15 (20).
H Dekigai, H Nakamura, J Bai, M Tanito, H Masutani, K Hirota, H Matsui, M Murakami, J Yodoi (2001) Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes, 23-30. In Free Radic Res 35 (1).
K Hirota, G L Semenza (2001) Rac1 activity is required for the activation of hypoxia-inducible factor 1., 21166-72. In The Journal of biological chemistry 276 (24).
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K Hirota, M Murata, T Itoh, J Yodoi, K Fukuda (2001) Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation, 25953-25958. In J Biol Chem 276 (28).
T Itoh, T Namba, K Fukuda, G L Semenza, K Hirota (2001) Reversible inhibition of hypoxia-inducible factor 1 activation by exposure of hypoxic cells to the volatile anesthetic halothane., 225-9. In FEBS letters 509 (2).
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H Mori (2000) Effects of 6-formylpterin, a xanthine oxidase inhibitor and a superoxide scavenger, on production of nitric oxide in RAW 264.7 macrophages, 93-99. In Biochimica et Biophysica Acta (BBA) - General Subjects 1474 (1).
K Hirota, H Nakamura, T Arai, H Ishii, J Bai, T Itoh, K Fukuda, J Yodoi (2000) Geranylgeranylacetone enhances expression of thioredoxin and suppresses ethanol-induced cytotoxicity in cultured hepatocytes, 825-830. In Biochem Biophys Res Commun 275 (3).
T Namba, T M Ishii, M Ikeda, T Hisano, T Itoh, K Hirota, J P Adelman, K Fukuda (2000) Inhibition of the human intermediate conductance Ca(2+)-activated K(+) channel, hIK1, by volatile anesthetics, 95-101. In Eur J Pharmacol.
K Hirota, M Matsui, M Murata, Y Takashima, F S Cheng, T Itoh, K Fukuda, J Yodoi, Y Junji (2000) Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells., 177-82. In Biochemical and biophysical research communications 274 (1).
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J Takeuchi, K Hirota, T Itoh, R Shinkura, K Kitada, J Yodoi, T Namba, K Fukuda (2000) Thioredoxin inhibits tumor necrosis factor- or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinase, 83-92. In Antioxid Redox Signal 2 (1).
S J Wei, A Botero, K Hirota, C M Bradbury, S Markovina, A Laszlo, D R Spitz, P C Goswami, J Yodoi, D Gius (2000) Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation, 6688-6695. In Cancer Res.
A Nishiyama, T Ohno, S Iwata, M Matsui, K Hirota, H Masutani, H Nakamura, J Yodoi (1999) Demonstration of the interaction of thioredoxin with p40phox, a phagocyte oxidase component, using a yeast two-hybrid system, 155-159. In Immunol Lett 68 (1).
Y Takashima, K Hirota, H Nakamura, T Nakamura, K Akiyama, F.-S. Chen, M Maeda, J Yodoi (1999) Differential expression of glutaredoxin and thioredoxin during monocytic differentiation, 397-401. In Immunol Lett.
Y Makino, N Yoshikawa, K Okamoto, K Hirota, J Yodoi, I Makino, H Tanaka (1999) Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function, 3182-3188. In J Biol Chem 274 (5).
K Hirota, M Murata, Y Sachi, H Nakamura, J Takeuchi, K Mori, J Yodoi (1999) Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB., 27891-7. In The Journal of biological chemistry 274 (39).
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a Nishiyama, M Matsui, S Iwata, K Hirota, H Masutani, H Nakamura, Y Takagi, H Sono, Y Gon, J Yodoi (1999) Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression., 21645-50. In The Journal of biological chemistry 274 (31).
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M Ema, K Hirota, J Mimura, H Abe, J Yodoi, K Sogawa, L Poellinger, Y Fujii-Kuriyama (1999) Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300., 1905-14. In The EMBO journal 18 (7).
T Nakamura, T Ohno, K Hirota, A Nishiyama, H Nakamura, H Wada, J Yodoi (1999) Mouse glutaredoxin- cDNA cloning, high level expression in E. coli and its possible implication in redox regulation of the DNA binding activity in transcription factor PEBP2., 357-365. In Free Radic Res.
K Hirota, A Nishiyama, J Yodoi (1999) Reactive oxygen intermediates, thioredoxin, and Ref-1 as effector molecules incellular signal transduction, 2414-2419. In Tanpakushitsu Kakusan Koso.
S Hashimoto, K Matsumoto, Y Gon, S Furuichi, S Maruoka, I Takeshita, K Hirota, J Yodoi, T Horie (1999) Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha., 443-447. In Biochem Biophys Res Commun.
M Ueno, H Masutani, R J Arai, A Yamauchi, K Hirota, T Sakai, T Inamoto, Y Yamaoka, J Yodoi, T Nikaido (1999) Thioredoxin-dependent redox regulation of p53-mediated p21 activation., 35809-35815. In J Biol Chem.
広田　喜一 (1999) リン酸化シグナルとレドックスシグナルのクロストーク（生体応答学の新展開）, 179-183. In 医学のあゆみ.
H Tanaka, Y Makino, K Okamoto, K Hirota, J Yodoi, H Ogawa, K Umesono, I Makino (1998) Redox regulation of glucocorticoid receptor, 92. In Pathophysiology.
J Yodoi, A Nishiyama, T Oono, K Hirota, H Masutani (1998) Thioredoxin target molecules in redox signal cascade, 92. In Pathophysiology.
S Iwata, T Hori, N Sato, K Hirota, T Sasada, A Mitsui, T Hirakawa, J Yodoi (1997) Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state, 3108-3117. In J Immunol 158 (7).
K Hirota, M Matsui, S Iwata, a Nishiyama, K Mori, J Yodoi (1997) AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1., 3633-8. In Proceedings of the National Academy of Sciences of the United States of America 94 (8).
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A Nishiyama, K Furuke, K Hirota, H Masutani, J Yodoi (1997) Detection of a nuclear 60-kDa protein coimminoprecipitates with human thiordoxin., 464-468. In Keio university synposia for life science and medicine.
T Tanaka, Y Nishiyama, K Okada, K Hirota, M Matsui, J Yodoi, H Hiai, S Toyokuni (1997) Induction and nuclear translocation of thioredoxin by oxidative damage in the mouse kidney: independence of tubular necrosis and sulfhydryl depletion, 145-155. In Lab Invest 77 (2).
R Yamaguchi, Y Mazaki, K Hirota, S Hashimoto, H Sabe (1997) Mitosis specific serine phosphorylation and downregulation of one of the focal adhesion protein, paxillin, 1753-1761. In Oncogene 15 (15).
Y Akamatsu, T Ohno, K Hirota, H Kagoshima, J Yodoi, K Shigesada (1997) Redox regulation of the DNA binding activity in transcription factor PEBP2. The roles of two conserved cysteine residues, 14497-14500. In J. Biol. Chem. 272 (23).
T Ohno, K Hirota, H Nakamura, H Masutani, T Sasada, J Yodoi (1997) Thioredoxin and its involvement in the redox regulation of transcription factors, NF-kB and AP-1, 450-456. In Keio university synposia for life science and medicine.
T Maruyama, Y Kitaoka, Y Sachi, K Nakanoin, K Hirota, T Shiozawa, Y Yoshimura, S Fujii, J Yodoi (1997) Thioredoxin expression in the human endometrium during the menstrual cycle, 989-993. In Mol Hum Reprod 3 (11).
T Sasada, S Iwata, N Sato, Y Kitaoka, K Hirota, K Nakamura, a Nishiyama, Y Taniguchi, a Takabayashi, J Yodoi (1996) Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity., 2268-76. In The Journal of clinical investigation 97 (10).
Y Makino, K Okamoto, N Yoshikawa, M Aoshima, K Hirota, J Yodoi, K Umesono, I Makino, H Tanaka (1996) Thioredoxin: a redox-regulating cellular cofactor for glucocorticoid hormone action. Cross talk between endocrine control of stress response and cellular antioxidant defense system., 2469-77. In The Journal of clinical investigation 98 (11).
H Masutani, K Hirota, T Sasada, Y Ueda Taniguchi, Y Taniguchi, H Sono, J Yodoi (1996) Transactivation of an inducible anti-oxidative stress protein, human thioredoxin by HTLV-I Tax, 67-71. In Immunol Lett 54 (2-3).
Yoshifumi Sachi, Kiichi Hirota, Hiroshi Masutani, Ken-ichi Toda, Takashi Okamoto, Masahiro Takigawa, Junji Yodoi (1995) Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells, 189-193. In Immunol Lett.
M Matsui, Y Taniguchi, K Hirota, M Taketo, J Yodoi (1995) Structure of the mouse thioredoxin-encoding gene and its processed pseudogene, 165-1119. In Gene 152 (2).
広田　喜一, 豊国　伸哉, 淀井　淳司 (1995) レドックス反応の起源と進化, 537-545. In 科学(岩波書店）.
H Morikawa, K Hirota, K Kito, H Fujita, S Mishima (1994) Re-expansion pulmonary oedema following removal of intrathoracic haematoma., 518-520. In Acta Anaesthesiol Scand.
Kawaguchi M, Hirota K, Kai S, Konishi N, Furuya H. Kawano Y Effects of n-propyl gallate on neuronal survival after forebrain ischemia in rats.. In Resuscitation.
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