Philip Fowler, PhD
Oxford, United Kingdom
Research field: Biological Sciences - Biophysics
Computational Biophysics
Membrane Proteins
Free energy calculations
Mechanics and physics of proteins
Publications
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Journal Article (18)
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Philip W Fowler, Mark S. P. Sansom (2013) The pore of voltage-gated potassium ion channels is strained when closed, 1872. In Nature Communications.Download PDF (1.26 MB)Download PDF (4.77 MB)
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Philip W. Fowler, Marcella Orwick-Rydmark, Nicolae Solcan et al. (2013) Using DEER, Modelling and Simulations to Investigate the Dynamics of PepTSo, a Major Facilitator Superfamily Transporter of Biomedical Importance, 199a. In Biophys J 104 (2).
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Nicolae Solcan, Jane Kwok, Philip W Fowler et al. (2012) Alternating access mechanism in the POT family of oligopeptide transporters., 3411-21. In EMBO J 31 (16).http://www.nature.com/doifinder/10.10...
http://www.ncbi.nlm.nih.gov/pubmed/22...
http://www.pubmedcentral.nih.gov/arti...
Download PDF (1.55 MB)Download PDF (6.66 MB)Download PDF (165.41 KB) -
Simon Newstead, David Drew, Alexander D Cameron et al. (2011) Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2., 417-426. In EMBO J 30 (2).Download PDF (1.06 MB)Download PDF (12.1 MB)
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Jennifer J Paynter, Isabelle Andres-Enguix, Philip W Fowler et al. (2010) Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains., 40754 -40761. In J Biol Chem 285 (52).Download PDF (1.34 MB)Download PDF (1.4 MB)
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Enrique Abad, J Reingruber, P. Fowler et al. (2009) A Novel Rate Theory Approach To Transport In Ion Channels, 236-243. In AIP Conf Proc.Download PDF (753.46 KB)
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Simon Newstead, Philip W Fowler, Paul Bilton et al. (2009) Insights into how nucleotide-binding domains power ABC transport., 1213-22. In Structure 17 (9).
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Emi Psachoulia, Philip W Fowler, Peter J Bond et al. (2008) Helix-helix interactions in membrane proteins: coarse-grained simulations of glycophorin a helix dimerization., 10503-12. In Biochemistry 47 (40).Download PDF (2.67 MB)
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Philip W Fowler, Kaihsu Tai, Mark S P Sansom (2008) The selectivity of K+ ion channels: testing the hypotheses., 5062-72. In Biophys J 95 (11).Download PDF (701.06 KB)Download PDF (1.77 MB)
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Markus Rapedius, Jennifer J Paynter, Philip W Fowler et al. (2007) Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing., 327-30. In Channels 1 (5).Download PDF (247.75 KB)
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Book Section (1)
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Kaihsu Tai, Philip W Fowler, Younes Mokrab et al. (2008) Molecular modeling and simulation studies of ion channel structures, dynamics and mechanisms., 233-65. In Methods in Cell Nano Biology.
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Conference Proceedings (1)
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Philip W Fowler, P V Coveney, S Jha et al. (2004) Exact calculation of peptide-protein binding energies by steered thermodynamic integration using high performance computing grids. In Proceedings of the UK e-Science All Hands Meeting.Download PDF (133.01 KB)
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Thesis (1)
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Philip W Fowler (2006) Qualitative and Quantitative Aspects of Biomolecular Systems Revealed by Large Scale and Grid Computing Methods.Download PDF (18.48 MB)
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CV
Professional Experience
2008 - Present
2006 - Present
Postdoctoral Researcher at SBCB Unit, Department of Biochemistry, University of Oxford
Oxford, United Kingdom
Classes taught:
First year biophysics: Non-covalent interactions
First year biophysics: Folding of macromolecules
Oxford, United Kingdom
Classes taught:
First year biophysics: Non-covalent interactions
First year biophysics: Folding of macromolecules
Education
Aug 2002 - Feb 2006
Oct 1994 - Jun 1998
Clare College, Cambridge
in Cambridge, United Kingdom
MSci in Natural Sciences
MSci in Natural Sciences
Contact Information

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