A framework for studying the neurobiology of value-based decision making.

Recent work has emphasized the role that orbitofrontal cortex (OFC) has in value-based decision-making. However, it is also clear that a number of discrepancies have arisen when comparing the findings from animal models to those from humans. Here,…

The effective management of knowledge is critical for organizations that are striving to gain or maintain a competitive advantage and that are in the process of re-structuring for the new century. Decision-making is an important factor for growing…

In recent years, disturbances in cognitive function have been increasingly recognized as important symptomatic phenomena in neurodegenerative diseases, including Parkinson's Disease (PD). Value-based decision making in particular is an important…

In some decision contexts, such as a crisis or when confronted by a new or novel set of circumstances, people may be forced to make decisions with limited information or time available for analysis. In such contexts, the set of alternative solutions…

Surviving in a world with hidden rewards and dangers requires choosing the appropriate behaviours. Recent discoveries indicate that the habenula plays a prominent part in such behavioural choice through its effects on neuromodulator systems, in…

Humans live in highly complex social environments and some of our most important decisions are made in the context of social interactions. Research that probes the neural basis of decision-making in the context of social interactions combines…

Despite a recent surge of interest, the subject of pricing in general and value-based pricing in particular has received little academic investigation. Yet, pricing has a huge impact on financial results, both in absolute terms and relative to other…

Over the past two decades significant progress has been made toward understanding the neural basis of primate decision making, the biological process that combines sensory data with stored information to select and execute behavioral responses. The…

Relatively few studies in MIS research have examined systems to support value-based decision-making behavior. The increasing complexity of the decision environment necessitates more reliance on personal values by decision-makers, thus making it an…

The work described here aims to isolate the component processes of decision making that rely critically on particular subregions of the human prefrontal cortex, with a particular focus on the orbitofrontal cortex. Here, experiments isolating…