Circular analysis in systems neuroscience: the dangers of double dipping.

A neuroscientific experiment typically generates a large amount of data, of which only a small fraction is analyzed in detail and presented in a publication. However, selection among noisy measurements can render circular an otherwise appropriate…

PROPOSAL DEADLINE: Preference will be given to proposals received by September 16, 2011; proposals received by October 28, 2011 will be considered, if space is available A series of workshops will be held after the main Cosyne meeting. The goal is…

Paralysis after stroke or neurotrauma is among the leading causes of long term disability in adults. The development of braincomputer interface (BCI) systems that allow online classification of electric or metabolic brain activity and their…

OBJECTIVE The authors performed a comprehensive meta-analysis of task-based functional MRI studies of attention deficit hyperactivity disorder (ADHD). METHOD The authors searched PubMed, Ovid, EMBASE, Web of Science, ERIC, CINAHAL, and NeuroSynth…

The complexity of the brain and the protean nature of behavior remain the most elusive area of science, but also the most important. van Hemmen and Sejnowski invited 23 experts from the many areas-from evolution to qualia-of systems neuroscience to…

The development of effective pharmacotherapy for obesity will benefit from a more complete understanding of the neural pathways and the neurochemical signals whose actions result in the reduction of the size of meals. This review examines the neural…

A fundamental challenge for systems neuroscience is to quantitatively relate its three major branches of research: brain-activity measurement, behavioral measurement, and computational modeling. Using measured brain-activity patterns to evaluate…

Placing a patient in a state of general anesthesia is crucial for safely and humanely performing most surgical and many nonsurgical procedures. How anesthetic drugs create the state of general anesthesia is considered a major mystery of modern…

We present a special focus on computational and systems neuroscience, highlighting recent advances in combining empirical and theoretical approaches, including work presented at the Cosyne meeting in past years.

'Form follows function' is an architectural philosophy attributed to the great American architect Louis Sullivan, and later taken up by the Bauhaus movement. It stresses that the form of a building should reflect its function. Neuroscientists have…