The Comprehensive Clinical Research Network; implications for urological research in England

This meeting report summarizes advances and notable developments in the pharmaceutical management of urological diseases presented at various sessions during the Annual Meeting of the American Urological Association held in Anaheim, California, June…

OBJECTIVE To determine how the reliability of frequency-volume charts (FVCs) vary with their duration when used to assess patients with lower urinary tract symptoms (LUTS) and whether the duration influences patient compliance.METHODS Peer-reviewed…

BACKGROUND: Monitoring and researching clinical care calls for comprehensive clinical databases. In mental health care these need to cover all aspects of the care of each patient and to accommodate the complexity of care which may last from weeks to…

The United Kingdom is trying to bring more non-governmental funding into NHS research through partnerships with the commercial and voluntary sectors. But it is still unclear exactly how the reforms in England will work and how trusts will resolve…

In recent years, there has been substantial investment in clinical research in the National Health Service (NHS) in England. This contribution reviews these developments, their strong focus on benefit for patients and public health, and the specific…

Disciplinary fragmentation and nosological and semantic controversies have obscured the impressive advances made in the area of depressive disorders during the past decade. This article is an attempt to translate data derived from psychodynamic,…

The Asthma Clinical Research Network was created by the National Heart, Lung, and Blood Institute to improve public health by rapidly evaluating novel and existing therapeutic approaches to asthma. The multicenter clinical research network has…

Because there is reason to believe that genetic variants could account for different treatment responses in subjects with asthma, it is important to collect blood for genetic-analysis purposes when conducting clinical trials in asthma. This article…

In any clinical trial, recruitment of trial participants usually requires an intense effort to reach the target sample size. The Asthma Clinical Research Network (ACRN) was keenly aware of this issue at its inception and therefore initiated and…

PURPOSE: We present a systematic study of the anatomical relationships between intrarenal arteries and the kidney collecting system in pigs. MATERIALS AND METHODS: The intrarenal anatomy (collecting system and arteries) was studied in 91,…