Confirming white matter fMRI activation in the corpus callosum: co-localization with DTI tractography.

Recently, functional magnetic resonance imaging (fMRI) activation has been detected in white matter, despite the widely-held belief that fMRI activation is restricted to gray matter. The objective of the current study was to determine whether the…

The ability to detect fMRI activation in white matter has been a matter of considerable debate. We have recently reported the first two prospective 4T fMRI studies, which used interhemispheric transfer tasks to elicit activation in the corpus…

Morphology of the corpus callosum (CC) at the mid-sagittal level has been a target of extensive studies. However, the lack of internal structures and its polymorphism make it a challenging task to quantitatively analyze shape differences among…

Morphology of the corpus callosum (CC) at the mid-sagittal level has been a target of extensive studies. However, the lack of internal structures and its polymorphism make it a challenging task to quantitatively analyze shape differences among…

Functional magnetic resonance imaging (fMRI) activation in white matter is controversial. Given that many of the studies that report fMRI activation in white matter used high field MRI systems, we investigated the field strength dependence of…

Autism spectrum disorders (ASD) is a heterogeneously neurodevelopmental disorder, that is characterized by impaired social reciprocity, communication difficulties, and restricted interest. To observe the abnormal brain connectivity in ASD, the…

Background: It is generally believed that activation in functional magnetic resonance imaging (fMRI) is restricted to gray matter. Despite this, a number of studies have reported white matter activation, particularly when the corpus callosum is…

Structural, volumetric, and microstructural abnormalities have been reported in the white matter of the brain in individuals with phenylketonuria (PKU). Very little research, however, has been conducted to investigate the development of white matter…

BACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of white matter development. We hypothesized that the early postnatal development of the corpus callosum and corticospinal tracts could be studied in unsedated…

We assessed sex differences in fractional anisotropy (FA) and mean diffusion (MD) of temporal lobe white matter (TLWMFA, TLWMMD), TLWM asymmetry, and the relationship between TLWM asymmetry and FA and MD of the corpus callosum (CCFA, CCMD) using…