Negative association between amyloid plaques and cerebral amyloid angiopathy in Alzheimer's disease.
by
J Tian,
J Shi,
K Bailey,
D M A Mann
Related research
-
J Tian, J Shi, K Bailey, C L Lendon, S M Pickering-Brown, D M A Mann in Journal of Neurology, Neurosurgery & Psychiatry (2004)OBJECTIVE: To investigate the association between white matter damage, as evidenced by myelin loss (ML), the extent of cerebral amyloid angiopathy (CAA), or arteriosclerosis (Art), and apolipoprotein E (ApoE) e4 allele in Alzheimer's disease (AD),…Save reference to library · Related research 5 readers
-
T I Mandybur in Neurology (1975)The incidence and forms of cerebral amyloid angiopathy were studied in 15 cases of Alzheimer's disease using Congo red staining and polarization. Thirteen cases showed slight to severe involvement; two contained no amyloid vascular degeneration.…Save reference to library · Related research 2 readers
-
J M Olichney, L A Hansen, D Galasko, T Saitoh, C R Hofstetter, R Katzman, in Neurology (1996)OBJECTIVE: To determine the relationship between apolipoprotein E (apoE) genotype and neuropathologic lesions in Alzheimer's disease (AD) and Lewy body variant (LBV). DESIGN: Retrospective genetic-neuropathologic study of AD and LBV cases. The main…Save reference to library · Related research 4 readers
-
Donna M Wilcock, Marcia N Gordon, Dave Morgan in Nature Protocols (2006)In the current protocol, we describe the Congo red staining method and a method for separately quantifying vascular and parenchymal amyloid deposits in brain tissue sections. Congo red staining detects amyloid deposits in brain tissue of amyloid…Save reference to library · Related research 22 readers
-
Dietmar Rudolf Thal, W Sue T Griffin, Rob A I De Vos, Estifanos Ghebremedhin in Acta Neuropathologica (2008)Cerebral amyloid angiopathy (CAA) is characterized by the deposition of the amyloid beta-protein (A beta) within cerebral vessels. The involvement of different brain areas in CAA follows a hierarchical sequence similar to that of Alzheimer-related…Save reference to library · Related research 37 readers
-
Z J Jiang, J S Richardson, P H Yu in Neuropathology and Applied Neurobiology (2008)Semicarbazide-sensitive amine oxidase (SSAO) catalyses the oxidative deamination of a variety of endogenous substrates, such as methylamine and aminoacetone, to produce highly reactive aldehydes, which are capable of inducing protein cross-linkage,…Save reference to library · Related research 2 readers
-
Z K Van Helmond, J S Miners, E Bednall, K A Chalmers, Y Zhang, G K Wilcock, et al. in Neuropathology and Applied Neurobiology (2007)Cerebral amyloid angiopathy (CAA) affects over 90% of patients with Alzheimer's disease (AD) and increases the risk of cerebral haemorrhage and infarction. Caveolae-cholesterol-enriched plasmalemmal microinvaginations-are implicated in the…Save reference to library · Related research 5 readers
-
D R Premkumar, D L Cohen, P Hedera, R P Friedland, R N Kalaria in The American journal of pathology (1996)The presence of apolipoprotein E-epsilon4 (APOE-epsilon4) allele has been implicated as a risk factor for Alzheimer's disease (AD). We examined the frequencies of APOE-epsilon4 alleles in age-matched controls and subgroups of 190 AD subjects…Save reference to library · Related research 10 readers
-
Kenichi Oshima, Hirotake Uchikado, Dennis W Dickson in International journal of clinical and experimental pathology (2008)Cerebral amyloid angiopathy (CAA) affects both leptomeningeal and parenchymal blood vessels and is common in Alzheimer's disease (AD). In some vessels, CAA is accompanied by localized neuritic dystrophy around the affected blood vessel. The aim of…
-
S Williams, K Chalmers, G K Wilcock, S Love in Neuropathology and Applied Neurobiology (2005)Over 90% of patients with Alzheimer's disease (AD) develop cerebral amyloid angiopathy (CAA). Severe dyshoric CAA, in which amyloid extends into the surrounding brain parenchyma, may be associated with adjacent clustering of tau-immunopositive…Save reference to library · Related research 4 readers
Readership Statistics
Readership statistics are being calculated.
Sign up today - FREE
Mendeley saves you time finding and organizing research. Learn more
- All your research in one place
- Add and import papers easily
- Access it anywhere, anytime
