DNA sequence represents a single format onto which a broad range of biological phenomena can be projected for high-throughput data collection. Over the past three years, massively parallel DNA sequencing platforms have become widely available,…
Papers
Papers
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There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of…
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The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include…
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The two most commonly used methods to analyze data from real-time, quantitative PCR experiments are absolute quantification and relative quantification. Absolute quantification determines the input copy number, usually by relating the PCR signal to…
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Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform,…
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Ten years after the publication of the position paper The hallmarks of cancer (Hanahan and Weinberg Cell 100:5770, 2000), it has become increasingly clear that mutated cells on their way to giving rise to a tumor have also to learn how to thrive in…
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RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-sequencing technologies. Studies using this method have already altered our view of the extent and complexity of eukaryotic transcriptomes. RNA-Seq also provides a…
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In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers aware of the importance of not using the terms moderator and mediator…
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There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of…
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We describe a model-based clustering method for using multilocus genotype data to infer population structure and assign individuals to populations. We assume a model in which there are K populations (where K may be unknown), each of which is…
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Error bars commonly appear in figures in publications, but experimental biologists are often unsure how they should be used and interpreted. In this article we illustrate some basic features of error bars and explain how they can help communicate…
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There is now ample evidence of the ecological impacts of recent climate change, from polar terrestrial to tropical marine environments. The responses of both flora and fauna span an array of ecosystems and organizational hierarchies, from the…
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Insights into conducting research and the writing of scientific papers are given by Prof. Whitesides in this short essay. The manuscript and its guidelines has been circulated within the Whitesides' research group since 1989.
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The tutorial starts with an overview of the concepts of VC dimension and structural risk minimization. We then describe linear Support Vector Machines (SVMs) for separable and non-separable data, working through a non-trivial example in detail. We…
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Computing as you know it is about to change, your applications and documents are going to move from the desktop into the cloud. I'm talking about cloud computing, where applications and files are hosted on a "cloud" consisting of thousands of…
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Note: OCR errors may be found in this Reference List extracted from the full text article. ACM has opted to expose the complete List rather than only correct and linked references.
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The dynamic capabilities framework analyzes the sources and methods of wealth creation and capture by private enterprise firms operating in environments of rapid technological change. The competitive advantage of firms is seen as resting on…
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We have designed and implemented the Google File System, a scalable distributed file system for large distributed data-intensive applications. It provides fault tolerance while running on inexpensive commodity hardware, and it delivers high…
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Provided certain obstacles are overcome, we believe Cloud Computing has the potential to transform a large part of the IT industry, making software even more attractive as a service and shaping the way IT hardware is designed and purchased.…
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We are developing a dual panel breast-dedicated PET system using LSO scintillators coupled to position sensitive avalanche photodiodes (PSAPD). The charge output is amplified and read using NOVA RENA-3 ASICs. This paper shows that the coincidence…
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Because continuous rating scales can provide the same aggregate information yet provide greater discrimination at an individual level of measurement, continuous semantic differential rating scales have an advantage in studies where individual…
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In this part, the life-cycle and development of Dactylogyrus vastator attacking carp in northern Bavaria are described. Under normal conditions in summer, individuals live up to 14 days at 17 deg C. Food includes the blood of the host. The place of…
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Dactylogyrus vastator attacking carp in rearing ponds in northern Bavaria was investigated. Methods used are described. This first part of the paper covers distribution, basic details of infection (size of fish infected, localization of the…
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In this part, the life-cycle and development of Dactylogyrus vastator attacking carp in northern Bavaria are described. Under normal conditions in summer, individuals live up to 14 days at 17 deg C. Food includes the blood of the host. The place of…
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Dactylogyrus vastator attacking carp in rearing ponds in northern Bavaria was investigated. Methods used are described. This first part of the paper covers distribution, basic details of infection (size of fish infected, localization of the…
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Dactylogyrus vastator attacking carp in rearing ponds in northern Bavaria was investigated. Methods used are described. This first part of the paper covers distribution, basic details of infection (size of fish infected, localization of the…
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In this part, the life-cycle and development of Dactylogyrus vastator attacking carp in northern Bavaria are described. Under normal conditions in summer, individuals live up to 14 days at 17 deg C. Food includes the blood of the host. The place of…
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This study was carried out to investigate the effect of EFDC hydrodynamic result on the WASP7.3 water quality modeling result in accordance with the change of number of grid for the dam reservoir to be constructed. The simulated flow and BOD, T-N…
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Body-worn equipment is a device used for diagnostics and health monitoring in Wireless Body Area Networks (WBANs). Ultra Wideband (UWB) technology is one of the possible technologies for WBAN on-body communication utilized in the IEEE 802.15.6,…
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O crescente descaminho de produtos, principalmente no âmbito dos bens de consumo, gerou nos últimos anos grande prejuízo para a economia de inúmeras empresas brasileiras. Esse comércio ilegal é extremamente comum no meio marítimo, mas, infelizmente,…
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Historical approaches to sexuality, in and outside of biblical studies, have tended to stress either continuities or ruptures. Yet, such approaches set a series of limits for tracing and assessing dynamics of gender, sexuality, and embodiment, where…
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The differing views that various parties and states hold regarding the efficacy of their Islamisation approach and its impact nationally remain unresolved until today. This paper is an attempt to assess the well-being of countries in an objective…
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The differing views that various parties and states hold regarding the efficacy of their Islamisation approach and its impact nationally remain unresolved until today. This paper is an attempt to assess the well-being of countries in an objective…
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The effect of varying the water content of a range of water-in-diesel fuel emulsions on the combustion process in a confined continuously burning spray, while keeping other parameters constant, is described. Experimental measurements of the…
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本研究では髪の色が人物印象に与える効果と顔の平凡性-個性との関係について検討した80名の被験者に画像処理によって髪の色を変化させた日本人男女の顔画像を呈示し16の印象評定項目について7段階尺度を用い印象評定を行なった得られたデータをもとに因子分析を行なった結果一般的望ましさ快活性の2因子が抽出された各顔刺激の平均評定値を用いて分散分析を行なった結果一般的望ましさ快活性の因子それぞれにおいて髪の色の効果が認められたまた髪の色と顔の平凡性-個性の交互作用が認められたこれは髪の色は顔の印象形成に影響…
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その実証的な研究史にふれながら, 対人融和のダイナミズムを探る. まず, 先天的な視覚障害者で観察された表出行動について述べる. 次に, This review represents to identify and discuss emotional meanigs through the nonverbal communication on interpersonal relations. The origin of communicative movements as to…
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本研究では髪の色が人物印象に与える効果と顔の平凡性-個性との関係について検討した80名の被験者に画像処理によって髪の色を変化させた日本人男女の顔画像を呈示し16の印象評定項目について7段階尺度を用い印象評定を行なった得られたデータをもとに因子分析を行なった結果一般的望ましさ快活性の2因子が抽出された各顔刺激の平均評定値を用いて分散分析を行なった結果一般的望ましさ快活性の因子それぞれにおいて髪の色の効果が認められたまた髪の色と顔の平凡性-個性の交互作用が認められたこれは髪の色は顔の印象形成に影響…
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その実証的な研究史にふれながら, 対人融和のダイナミズムを探る. まず, 先天的な視覚障害者で観察された表出行動について述べる. 次に, This review represents to identify and discuss emotional meanigs through the nonverbal communication on interpersonal relations. The origin of communicative movements as to…
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We analyse molecular and phenotypic evolution in a group of taxonomically problematic Indomalayan pitvipers, the Trimeresurus sumatranus group. Mitochondrial DNA sequencing provides a well-resolved phylogeny, with each species representing a…
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To overcome the ambiguity of the concept of sustainable agriculture in surveys of personal definitions of this phenomenon, a semi-structured approach allowing respondents to provide their own definitions was employed. Agricultural faculty at a…
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