We tested the hypothesis that single nucleotide polymorphisms (SNPs) within genes of the NF-κB pathway are associated with altered clinical outcome of septic shock patients. We genotyped 59 SNPs in the NF-κB pathway in a discovery cohort of septic…
Papers in Chemistry
Miscellaneous papers in Chemistry, A
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The first image sensor with submicron pixel pitch is reported. Test structures comprising 16 x 16 pixel full-frame-transfer (FFT) CCDs with 0.5 μm pixels are fabricated in a single-poly 110 nm CMOS process. Characterization results demonstrate…
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Epidemiological studies suggest that smoking reduces the risk for Parkinson's disease. It has been hypothesized that inhibition of monoamineoxidase contributes to this action. The present study examined the contribution of the beta-carbolines…
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A 0.79-mm2 29-mW real-time face detection core is fabricated in a 0.13-mum CMOS technology. It consists of 75-kgate logic, 58-kbit SRAM, and an ARM AMBA bus interface. Comprehensive optimization in both algorithm and hardware design improves…
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A 0.9V third-order 1.5bit delta-sigma ADC with simple dynamic element matching (DEM) is presented. A fully-differential low-voltage double-sampling structure avoids use of clock boosting or bootstrapping. It operates from 0.65V to 1.5V supply with…
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A 10,000 member peptide nucleic acid (PNA) encoded peptide library was prepared, treated with the Abelson tyrosine kinase (Abl), and decoded using a DNA microarray and a fluorescently labeled secondary antiphosphotyrosine antibody. A dual-color…
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We present a sea-ice record from northern Greenland covering the past 10,000 years. Multiyear sea ice reached a minimum between ~8500 and 6000 years ago, when the limit of year-round sea ice at the coast of Greenland was located ~1000 kilometers to…
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A short sediment core (162 cm), covering the period AD 920-1999, was sampled from the south basin of Lake Winnipeg for a suite Of multi-proxy analyses leading towards a detailed characterisation of the recent millennial lake environment and…
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Retinal gamma-aminobutyric acid type C (GABAC) receptors are believed to be composed of rho subunits. Although rho 1 and rho 2 are over 80% similar, the whole-cell currents generated by rho 1 receptors in Xenopus oocytes are significantly greater…
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A stable 100-kD complex from mitochondria of Leishmania tarentolae containing two RNA-binding proteins, Ltp26 and Ltp28, was identified by cross-linking to unpaired 4-thiouridine nucleotides in a partially duplex RNA substrate. The genes were cloned…
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Investigation on a traveling-wave thermoacoustic electricity generator is presented. In the experiment, more than 100 W electrical power was achieved under 2.5 MPa mean pressure, 64 Hz working frequency and 0.2 MPa pressure amplitude.
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This study has worked on the evaluation of the temporal and spatial evolution of heavy metal contamination in sediment taken from a shallow eutrophic lake, Lake Chaohu, China, over the last 100 years, and thereby used (137)Cs and (210)Pb dating, a…
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RNase P from the mitochondria of Saccharomyces cerevisiae was purified to near homogeneity > 1800-fold with a yield of 1.6% from mitochondrial extracts. The most abundant protein in the purified fractions is, at 105 kDa, considerably larger than the…
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Human T-cell leukemia virus type 1 and type 2 (HTLV-1/2) are related retroviruses that infect T-lymphocytes. Whereas HTLV-1 infection can cause leukemia, HTLV-2 has not been demonstrated to be the agent of a hematological malignant disease.…
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Fluorescence resonance energy transfer (FRET) from the amino acid tryptophan (Trp) as donor and a 2,3-diazabicyclo2.2.2oct-2-ene-labeled asparagine (Dbo) as acceptor in peptides of the general structure Trp-(Pro)(n)-Dbo-NH2 (n = 1-6) was…
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Fluorescence resonance energy transfer (FRET) from the amino acid tryptophan (Trp) as donor and a 2,3-diazabicyclo2.2.2oct-2-ene-labeled asparagine (Dbo) as acceptor in peptides of the general structure Trp-(Pro)n-Dbo-NH2 (n = 1-6) was investigated…
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Fluorescence resonance energy transfer (FRET) from the amino acid tryptophan (Trp) as donor and a 2,3-diazabicyclo2.2.2oct-2-ene-labeled asparagine (Dbo) as acceptor in peptides of the general structure Trp-(Pro)n-Dbo-NH2 (n = 1-6) was investigated…
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A merged equalizer/CDR circuit employs a parallel-path equalizer and triple-loop adaptation to achieve a binary data rate of 10 Gb/s. Realized in 0.13mum CMOS technology, the circuit adapts to FR4 trace lengths up to 24 inches with BER<10-13 while…
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Previous studies have reported that the maternal behavior of rhesus monkey females who themselves were reared without mothers ("motherless mothers") is generally inadequate and often abusive. The present study examined teh maternal competency of 50…
Papers in associated sub-disciplines
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