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Papers in Nuclear Magnetic Resonance

Nuclear Magnetic Resonance papers in Chemistry, E

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Papers 1 - 20 of 697 in Nuclear Magnetic Resonance, E
  1. p53 is regulated by multiple posttranslational modifications, including Hdm2-mediated ubiquitylation that drives its proteasomal degradation. Here, we identify the p53-associated factor E4F1, a ubiquitously expressed zinc-finger protein first…
  2. Huntington disease (HD) is a fatal neurodegenerative disorder caused by an expanded CAG repeat. Its length can be used to estimate the time of clinical diagnosis, which is defined by overt motor symptoms. Non-motor symptoms begin before motor onset,…
  3. This article describes an approach to early process development in the context of the productivity model in legacy Wyeth (i.e. to deliver two New Drug Applications per year for New Molecular Entities). As a result of the model, the cycle time from…
  4. Palms are generally characterized by a large structure with a massive crown that creates difficulties in anatomical studies. The flowering behaviour of palm species may be a useful indicator of phylogenetic relationships and therefore evolutionary…
  5. The aims of this report are firstly to raise awareness among kineticists and pharmacologists as to why pharmacokinetic-pharmacodynamic (PKPD) integration is essential for target validation (TV), optimizing development of lead compounds (lead…
  6. Microstructural analysis of the early stage crystal growth of zeolite A in hydrothermal synthetic conditions revealed a revised crystal growth route from surface to core in the presence of the biopolymer chitosan. The mechanism of this extraordinary…
  7. We report a versatile and scalable synthesis of a water-dispersible modular star polymer platform with an enzyme-inspired hydrophobic interior. The cores of the stars can be functionalized at will, independently from the modification of the polymer…
  8. A changing environment and lifestyle on the background of evolutionary engraved or perinatally imprinted physiological response patterns is the foremost explanation for the current obesity epidemic. However, it is not clear what the mechanisms are…
  9. Echo-planar imaging is a fast magnetic resonance (MR) imaging technique that allows acquisition of single images in as little as 20 msec and performance of multiple-image studies in as little as 20 seconds. Echo-planar imaging achieves its speed by…
  10. Although land management over much of the history of the US. Fish and Wildlife Service's National Wildlife Refuge System (NWRS) has emphasized single-species management, recent policy has encouraged land managers to focus on broader ecosystem…
  11. The substitution of conventional fossil fuels with biomass for energy production results both in a net reduction of greenhouse gases emissions and in the replacement of non-renewable energy sources. However, at present, generating energy from…
  12. Two new schemes for heteronuclear broadband NMR long-range correlation are presented. One scheme employs the conventional low-pass J filter HMBC pulse sequence and combines spectra recorded with different excitation delays in order to achieve…
  13. Edible films and coatings are applied on many products to control moisture transfer, gas exchange or oxidation processes. One major advantage of using edible films and coatings is that several active ingredients can be incorporated into the polymer…
  14. New versions of the H2BC pulse sequence (Nyberg NT, Duus JØ, Sørensen OW. J. Am. Chem. Soc. 2005; 127: 6154) that edit into two subspectra according to the number of protons attached to 13C nuclei being odd or even are introduced. These sequences…
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