Find Research Papers
Earth Sciences
bpa
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| 3 |
| 2010 |
Bisphenol-A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response -- Bromer et al., 10.1096/fj.09-140533 -- The FASEB Journal
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bisphenol-A (BPA) is a nonsteroidal estrogen that is ubiquitous in the environment. The homeobox gene Hoxa10 controls uterine organogenesis, and its expression is affected by in utero BPA exposure. We hypothesized that an epigenetic mechanism…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2010 |
The Genomic Response of Ishikawa Cells to Bisphenol A Exposure is Dose- and Time-Dependent.
Toxicology
A reliable in vitro model to determine the potential estrogenic activity of chemicals of interest is still unavailable. To further investigate the usefulness of a human-derived cell line, we determined the transcriptional changes induced by…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures
Human exposure to bisphenol A is controversially discussed. This review critically assesses methods for biomonitoring of bisphenol A exposures and reported concentrations of bisphenol A in blood and urine of non-occupationally…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2002 |
Metabolism and kinetics of bisphenol a in humans at low doses following oral administration.
Chemical research in toxicology
Volume: 15 , Issue: 10 , Page: 1281-7
Bisphenol A is a widely used industrial chemical with many potential sources of human exposure. Bisphenol A is a weak estrogen and has been implicated as an "endocrine disruptor". This term is used for a variety of chemicals encountered…
Filed in Miscellaneous (Earth Sciences)
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| 4 |
Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring
Aims The exposure to endocrine disruptor (ED) induces functional and behavioral abnormalities associated with reproduction. Humans are ubiquitously exposed to Bisphenol A (BPA), an ED, as it leaches from polycarbonate plastics into their contents.…
Filed in Miscellaneous (Earth Sciences)
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| 5 |
| 2008 |
Derivation of a bisphenol A oral reference dose (RfD) and drinking-water equivalent concentration.
Journal of toxicology and environmental health. Part B, Critical reviews
Volume: 11 , Issue: 2 , Page: 69-146
Human exposure to bisphenol A (BPA) is due to that found in the diet, and BPA and its metabolites were detected at parts per billion (or less) concentrations in human urine, milk, saliva, serum, plasma, ovarian follicular fluid, and amniotic…
Filed in Miscellaneous (Earth Sciences)
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| 4 |
| 2009 |
Biodegradation of bisphenol A, bisphenol F and bisphenol S in seawater.
International journal of environmental research and public health
Volume: 6 , Issue: 4 , Page: 1472-84
A group of compounds structurally similar to bis(4-hydroxyphenyl)propane (bisphenol A, BPA) are called bisphenols (BPs), and some of them can partially replace BPA in industrial applications. The production and consumption of BPs other than BPA,…
Filed in Miscellaneous (Earth Sciences)
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| 5 |
| 2008 |
Long-term study of urinary bisphenol A in elementary school children.
Environmental health and preventive medicine
Volume: 13 , Issue: 6 , Page: 332-7
OBJECTIVES: Due to its industrial application and frequent use as a coating material for food containers, bisphenol A (4,4'-isopropylidenediphenol, BPA) is present in abundance in our environment. Data on intake levels of BPA are limited in…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2002 |
Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols.
Environmental toxicology
Volume: 17 , Issue: 1 , Page: 80-6
Although abundant data are available on the toxicity of bisphenol-A (2,2-bis (4-hydroxydiphenyl)propane; BPA), little is known about the toxicities of the structurally similar compounds, namely bisphenols (BPs). A variety of BPs were examined for…
Filed in Miscellaneous (Earth Sciences)
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| 5 |
| 2010 |
Plastics and Health Risks.
Annual review of public health
By 2010, the worldwide annual production of plastics will surpass 300 million tons. Plastics are indispensable materials in modern society, and many products manufactured from plastics are a boon to public health (e.g., disposable syringes,…
Filed in Miscellaneous (Earth Sciences)
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| 2 |
| 2010 |
Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators.
International journal of andrology
Summary The inappropriate programming of developing organ systems by exposure to excess native or environmental steroids, particularly the contamination of our environment and our food sources with synthetic endocrine disrupting chemicals that can…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2010 |
Novel roles of prolactin and estrogens in breast cancer: resistance to chemotherapy.
Endocrine-related cancer
Resistance to chemotherapy is a major complication in the treatment of advanced breast cancer. Estrogens and prolactin (PRL) are implicated in the pathogenesis of breast cancer but their roles in chemoresistance have been overlooked. A common…
Filed in Miscellaneous (Earth Sciences)
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| 5 |
| 2009 |
Risk assessment of bisphenol A migrated from canned foods in Korea.
Journal of toxicology and environmental health. Part A
Volume: 72 , Issue: 21-22 , Page: 1327-35
Exposure and risk assessment of bisphenol A (BPA) was conducted on consumption of canned foods in Korean adults. Sixty-one canned food items with different brands purchased from retail outlets in markets were analyzed for BPA concentration by…
Filed in Miscellaneous (Earth Sciences)
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| 2 |
| 2009 |
Potencies of bisphenol A on the neuronal differentiation and hippocampal neurogenesis.
Journal of toxicology and environmental health. Part A
Volume: 72 , Issue: 21-22 , Page: 1343-51
Endocrine-disrupting chemicals (EDC) produce adverse effects on reproductive and immune function or neurological behavior, and may also induce cancer. The environmental EDC bisphenol A (BPA) is widely used in the manufacture of plastics and epoxy…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2010 |
Pharmacological Modulation of Genome and Proteome Alterations in Mice Treated with the Endocrine Disruptor Bisphenol A.
Current cancer drug targets
Among endocrine disruptors, the xenoestrogen bisphenol A (BPA) is of particular interest due to the very high production and widespread environmental contamination. We recently demonstrated that the oral administration of BPA to mice results in…
Filed in Miscellaneous (Earth Sciences)
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| 3 |
| 2000 |
Metabolic inactivation of five glycidyl ethers in lung and liver of humans, rats and mice in vitro.
Xenobiotica; the fate of foreign compounds in biological systems
Volume: 30 , Issue: 5 , Page: 485-502
1. Some glycidyl ethers (GE) have been shown to be direct mutagens in short-term in vitro tests and consequently GE are considered to be potentially mutagenic in vivo. However, GE may be metabolically inactivated in the body by two different…
Filed in Miscellaneous (Earth Sciences)
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| 4 |
| 2001 |
Defining the Impact of Weakly Estrogenic Chemicals on the Action of Steroidal Estrogens
Toxicological Sciences
Volume: 60 , Issue: 2 , Page: 296-304
We tested whether bisphenol A (BPA) or o,p'-DDT, when combined with 17beta-estradiol (E2), would contribute to the overall mixture effect using a yeast reporter gene assay, the yeast estrogen screen. Following comprehensive…
Filed in Miscellaneous (Earth Sciences)
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| 2 |
| 2008 |
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Carcinogenesis
Volume: 29 , Issue: 10 , Page: 1862-8
Reports of the ability of estrogenic agents such as 17beta-estradiol (E2), estriol (E3) and bisphenol A (BPA) to induce micronuclei (MN) in MCF-7 breast cancer cells have prompted us to investigate whether these effects are linked to activation of…
Filed in Miscellaneous (Earth Sciences)
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| 4 |
| 2007 |
Epigenetics in reproductive medicine.
Pediatric research
Volume: 61 , Issue: 5 Pt 2 , Page: 51R-57R
Imprinted genes comprise a small subset of the genome whose epigenetic reprogramming in the germ line is necessary for subsequent normal embryonic development. This reprogramming and resetting of the imprints, through an…
Filed in Miscellaneous (Earth Sciences)
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| 2 |
| 2008 |
Effects of endocrine disruptors on genes associated with 17beta-estradiol metabolism and excretion.
Steroids
Volume: 73 , Issue: 12 , Page: 1242-51
In order to provide a global analysis of the effects of endocrine disruptors on the hormone cellular bioavailability, we combined 17beta-estradiol (E2) cellular flow studies with real-time PCR and Western blot expression measurements of genes…
Filed in Miscellaneous (Earth Sciences)
