We tested the hypothesis that single nucleotide polymorphisms (SNPs) within genes of the NF-κB pathway are associated with altered clinical outcome of septic shock patients. We genotyped 59 SNPs in the NF-κB pathway in a discovery cohort of septic…
Papers in Computer Architecture
Computer Architecture papers in Computer and Information Science, A
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A 256Mb PRAM featuring synchronous burst read operation is developed. Using a charge-pump system, write performance is characterized at 1.8V supply. Measured initial read access time and burst-read access time are 62ns and 10ns, respectively. The…
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A low-power, single-chip, one-channel, fully implantable microtransponder system for low-frequency biomedical sensor applications is described. The circuit is powered by an external RF source at 27/40 MHz. No battery is required. Wireless…
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Pollen recovered from core tops of deep-sea cores from offshore northwestern Western Australia were used to build climatic transfer functions applied to sediment samples from major rivers bordering the ocean in the same region and a deep-sea core…
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As extracellular electrode arrays with 100 or more active recording sites become more widely used for simultaneous recording of neural ensembles, practical data acquisition systems that can efficiently accommodate high electrode counts are needed.…
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A technique has been developed for fabricating three dimensional "hair brush" electrode arrays from monocrystalline silicon blocks. Arrays consist of a square pattern of 100 penetrating electrodes, with 400 microns interelectrode spacing. Each…
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A 125 GOPS 583 mW Network-on-Chip Based Parallel Processor With Bio-Inspired Visual Attention EngineA network-on-chip (NoC) based parallel processor is presented for bio-inspired real-time object recognition with visual attention algorithm. It contains an ARM10-compatible 32-bit main processor, 8 single-instruction multiple-data (SIMD) clusters…
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Nehalem-EX is the most recent product in the family of the X86 Xeon microprocessors targeting high performance, low-power products 1, 2. Several key design requirements for this product include high bandwidth, low-latency shared L3 cache access,…
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This paper describes a 160 MHz 500 mW 32 b StrongARM(R) microprocessor designed for low-power, low-cost applications. The chip implements the ARM(R) V4 instruction set and is bus compatible with earlier implementations. The pin interface runs at 3.3…
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A 167-processor 65 nm computational platform well suited for DSP, communication, and multimedia workloads contains 164 programmable processors with dynamic supply voltage and dynamic clock frequency circuits, three algorithm-specific processors, and…
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A machine assembly consisting of 17 identical molecules of 2,3,5,6-tetramethyl-1-4-benzoquinone (DRQ) executes 16 instructions at a time. A single DRQ is positioned at the center of a circular ring formed by 16 other DRQs, controlling their…
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A 16-fold semi-microelectrode with 10 x 10 sq. microns contacts at distances of 150 microns, produced by means of thin-film technology, is described. These small dimensions are required to study the laminar electrophysiological differences within…
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A17 amacrine cells of the cat retina have been penetrated with horseradish peroxidase (HRP)-filled microelectrodes and their light responses recorded. These cells depolarize in sustained fashion to steps of light. Viewed in retinal wholemounts,…
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In emerging embedded applications such as wireless sensor networks, the key metric is minimizing energy dissipation rather than processor speed. Minimum energy analysis of CMOS circuits estimates the optimal operating point of clock frequencies,…
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Implantable biomedical devices can highly benefit from submicrometer CMOS technologies both in terms of duration-time increase and size shrinking. This work shows how design techniques for submicrometer CMOS technologies lead to improvements in the…
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Papers in associated sub-disciplines
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