G-Quadruplex DNA ligands are promising novel anticancer agents with potentially fewer side effects and greater selectivity than standard anticancer drugs. However, the design of G-quadruplex ligands remains challenging since known chemical features…
Papers in Language Education
Language Education papers in Education, C
-
-
Mass disasters such as e.g., plane or train crash, shipping accidents or huge explosions in the region of Slovak Republic are not very often, but in spite of this fact sometimes they occur. Such a terrible event-a destructive detonation of…
-
-
Dehydroepiandrosterone (DHEA), produced from cholesterol in the adrenals, is the most abundant steroid in our circulation. It is present almost entirely as the sulfate ester, but the free steroid is the form that serves as a precursor of estrogens…
-
The C-24 configuration of (22E,24xi)-24-isopropenyl-22-dehydrocholesterol (1), which was recently isolated from the Colombian Caribbean sponge, Topsentia ophiraphidites, was investigated. Synthesis of the stereodefined (24R)- and…
-
The hexane extracts of seeds of Ditaxis heterantha afforded two new apocarotenoids whose structures corresponded to methyl 3-oxo-12'-apo-epsilon-caroten-12'-oate (1) (heteranthin) and methyl…
-
Five C-27 apocarotenoids were detected in acetone extracts of the flowers of Boronia megastigma (Nees) using HPLC with UV-vis photodiode array and MS detection. Comparison of methylated and unmethylated extracts aided identification when considered…
-
Sex hormones and insulin have been implicated in articular cartilage metabolism. To supplement previous findings on the regulation of matrix synthesis with 17β-estradiol and insulin and to find a possible model to study cartilage metabolism in…
-
Investigation of the ecdysteroid constituents of the herb Ajuga reptans var. reptans resulted in the isolation of three new ecdysteroids, named reptanslactone A (2), reptanslactone B (3), and sendreisterone (5), and the known 24-dehydroprecyasterone…
-
Destruction of the second cervical vertebra leads to a highly unstable situation. Reconstruction is difficult because the axis plays a central role in rotatory movements and has a unique function in redistributing axial loads. The axis transfers the…
-
Alpha1-Antitrypsin (AAT), a major endogenous inhibitor of serine proteases, plays an important role in minimizing proteolytic injury to host tissue at sites of infection and inflammation. There is now increasing evidence that AAT undergoes…
-
Reaction of W(NCMe)(η(2)-PhCCPh)(3) with C(60) affords W(η(3)-NC(Me)C(60))(η(4),η(2)-C(6)Ph(6)) (2) and W(CPh)(NCMe)(η(2)-C(60)) (η(3),η(2)-C(5)Ph(5)) (3). The hexaphenylbenzene species of 2 shows an η(4)-butadiene + η(2)-olefin bonding mode and the…
-
Two ultrastructural approaches were used in photoreceptor cells of the leech, Hirudo medicinalis, to (a) investigate the intracellular topography of the smooth endoplasmic reticulum (SER) and (b) identify among the various subregions of the SER…
-
In 1995 Maver proposed seven deadly sins for CAAD as the prelude to a critical discussion on the principles, methods and practices of the field. In an attempt to return to this discussion, in this paper these sins are linked to the seven deadly sins…
-
-
The need for high performance per watt has led to the development of multi-core systems such as the Intel Core 2 Duo processor and the Intel quad-core Kentsfield processor. Maximal exploitation of the hardware parallelism supported by such systems…
-
The cache coherence mechanisms are a key component towards achieving the goal of continuing exponential performance growth through widespread thread-level parallelism. This dissertation makes several contributions in the space of cache coherence for…
-
The 12-core AMD Opteron processor, code-named "Magny Cours," combines advances in silicon, packaging, interconnect, cache coherence protocol, and server architecture to increase the compute density of high-volume commodity 2P/4P blade servers while…
-
We present a cache oblivious algorithm for stencil computations, which arise for example in finite-difference methods. Our algorithm applies to arbitrary stencils in n -dimensional spaces. On an "ideal cache" of size Z , our algorithm saves a factor…
-
Papers in associated sub-disciplines
Sign up today - FREE
Mendeley saves you time finding and organizing research. Learn more
- All your research in one place
- Add and import papers easily
- Access it anywhere, anytime