We tested the hypothesis that single nucleotide polymorphisms (SNPs) within genes of the NF-κB pathway are associated with altered clinical outcome of septic shock patients. We genotyped 59 SNPs in the NF-κB pathway in a discovery cohort of septic…
Papers in Mechanical Engineering
Mechanical Engineering papers in Engineering, A
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This paper describes the development of a new sled system that can address many safety-related issues pertaining to the racing industry. The system was designed to re-create acceleration and velocity levels similar to levels evident in race car…
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This paper reports a method for fabricating a 100 nm scale heater-thermometer into a silicon microcantilever based on contact photolithography and a controlled annealing process. The heater is formed during a photolithography process that can…
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This paper presents the design, simulation, fabrication, and testing results of a 1.14GHz piezoelectrically actuated disk resonator with electrostatic frequency tuning capability. The resonator is designed to suppress anchor loss by minimizing the…
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A CMOS sensor array for monitoring neural signals of living cells with 128 /spl times/ 128 pixels in a 1 mm/sup 2/ area is described. A standard 0.5 /spl mu/m, 5 V CMOS process extended by top electrodes covered by a relatively thin bio-compatible…
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A novel 12-station hip joint simulator with an anatomic position of the prosthesis was designed and built. The motion of the simulator consists of flexion-extension and abduction-adduction. The load is of the double-peak type. The validation test…
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A novel 12-station hip joint simulator with an anatomic position of the prosthesis was designed and built. The motion of the simulator consists of flexion-extension and abduction-adduction. The load is of the double-peak type. The validation test…
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The main challenge is to reduce the weight because the lift to drag ratio is known to naturally decrease with size, due to increasing viscous and boundary layer effects and no characterization of autonomous gliding has been provided so far. These…
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The paper A 99-line topology optimization code written in Matlab by Sigmund (Struct Multidisc Optim 21(2):120127, 2001) demonstrated that SIMP-based topology optimization can be easily implemented in less than hundred lines of Matlab code. The…
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The paper reports an investigation on the transient evolution of diesel flames in terms of fuel air mixing, spray penetration and combustion rate. A one-dimensional (1D) spray model, which was previously validated for inert diesel sprays, is…
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A 1-DOF Assistive Exoskeleton with Inertia Compensation : Effects on the Agility of Leg Swing MotionMany of the current implementations of exoskeletons for the lower extremities are con- ceived to either augment the users load-carrying capabilities or reduce muscle activation during walking. Comparatively little research has been conducted on…
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We propose a novel control method for lower- limb assist that produces a virtual modification of the me- chanical impedance of the human limbs. This effect is accom- plished through the use of an exoskeleton that displays active impedance. The…
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The photos of locomotives on the cover of this book illustrate the time period of interest in significant studies of metal fati- gue. The older Stephenson Locomotive 020 of 1833, displayed at the CNAM museum in Paris, is an example from the era of…
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OBJECTIVES: Evaluate the efficacy and safety of duloxetine at doses up to 120 mg once daily in patients with fibromyalgia. METHODS: This was a phase 3, 60-week study, which included an 8-week open-label period followed by a 52-week, randomized,…
Papers in associated sub-disciplines
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