A protein of mass 7643 Da and sequence identical to that of subunit c, the pore part, of the mitochondrial adenosine triphosphate synthase complex, was co-purified with cholesterol in crystals formed from a chloroform/methanol extract of bovine…
Papers in Physiology
Physiology papers in Medicine, A
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As extracellular electrode arrays with 100 or more active recording sites become more widely used for simultaneous recording of neural ensembles, practical data acquisition systems that can efficiently accommodate high electrode counts are needed.…
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IMR32, a neuroblastoma cell line, and CADO LC6, a small cell lung cancer (SCLC) cell line, extended neurite-like processes when cultured on fibronectin (FN)-coated surfaces or cultured in a serum-free medium. Monoclonal antibodies against the…
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The cariogenic potential of Streptococcus mutans is due to the production of organic acids derived from energy metabolism, which implies the need of mechanisms for the organism to tolerate this acidic environment. The F(1)F(o)-ATPase is generally…
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Numerous eukaryotic upstream promoter and enhancer regions contain a functional octamer sequence ATGCAAAT. We have examined the interactions between an octamer binding protein isolated from HeLa cells and the SV40 and immunoglobulin heavy-chain…
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Seven-transmembrane receptors (7TMRs) are a family of proteins of great interest as therapeutic targets because of their abundance on the cell surface, diverse effects in modulating cell behavior and success as a key class of drugs. We have…
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Hans Christian Geelmuyden (1861-1945) was amanuensis (assistant professor) at the Institute of Physiology, University of Oslo from 1889 to 1931. In 1897 he was awarded the degree "Doctor of Medicine" for his thesis "Om aceton som stofvexelprodukt"…
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This contribution to the centennial commemorative issue of the American Journal of Physiology: Gastrointestinal and Liver Physiology identifies some of the important studies of spontaneous electrical and motor activity in the gastrointestinal tract…
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One hundred years ago, in 1898, Professor Robert Tigerstedt, Karolinska institutet, Sweden, discovered renin. The subsequent elaboration in 1960 of the renin-angiotensin-aldosterone system signalled the start of modern hypertension research. The…
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Muscle electrical activity suppresses expression of the embryonic-type (alpha, beta, gamma, and delta) nicotinic acetylcholine receptor (nAChR) genes. The molecular mechanism by which electrical activity regulates these genes is not known. One…
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Amyloid beta (A beta), the major constituent of the fibrils composing senile plaques and vascular amyloid deposits in Alzheimer's disease (AD) and related disorders, is a 39-42-residue self-aggregating degradation peptide of a larger multidomain…
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The present experiments investigated the relationship between the spontaneous basal firing rate of A10 dopamine (DA) neurons and their sensitivity to the rate-suppressant effects of intravenously administered apomorphine (APO) and d-amphetamine…
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Rhythms at about 10 Hz were recorded from the primary visual cortex of the cat (anterior part of area 18), with characteristics close to those of the alpha rhythm in man: frequency band (7-14 Hz), localization and reactivity to visual stimulation.…
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Coherence analysis revealed that the 10-Hz rhythm in sympathetic nerve discharge (SND) was not correlated to that either in inferior olivary activity of decerebrate cats or in neocortical spindles of urethane-anesthetized cats. Also the discharges…
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University of Pennsylvania Smell Identification Test data from control subjects (n = 63), patients with mild cognitive impairment (n = 147), and patients with Alzheimer's disease (n = 100) were analyzed to derive an optimal subset of items related…
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Experiments were carried out with female tree-shrews (Tupaia belangeri). Following 6-hydroxydopamine injections into the ventral tegmental area, considerable variations in tyrosine-hydroxylase activity in the respective target regions of the A10…
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The transients of the tension and the angle of a first order diffraction line of isolated single intact muscle fibres of the M. lumbricalis IV of the foot resulting from rapid length changes have been measured. Furthermore simulations of the tension…
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The mesoaccumbens dopamine (DA) pathway is known to be involved in both the rewarding properties of cocaine and in behavioral sensitization to its locomotor-stimulating effects. We investigated changes in DA neurons in this pathway following…
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AIMS/HYPOTHESIS: We investigated whether a 10-s maximal sprint effort performed immediately prior to moderate-intensity exercise provides another means to counter the rapid fall in glycaemia associated with moderate-intensity exercise in individuals…
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PURPOSE: To compare the effects of a 10-week training program with two different exercises - traditional hamstring curl (HC) and Nordic hamstrings (NH), a partner exercise focusing the eccentric phase - on muscle strength among male soccer players.…
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