Advances in clinical science

Abstract

The book presents the latest developments in clinical medicine, particularly involved with pulmonary care and diseases. Emphasis is placed on the role of childhood obesity, often a result of the ill effects of an unhealthy diet and nutritional deficits, in shaping propensity for inflammatory pathologies, allergies, immune deficiency, and respiratory and cardiovascular sequelae in adult life. Oxidative damage, caused by not full well understood cellular biochemistry, when unchecked by antioxidative rescue mechanisms, takes toll on a respiratory health. The book underscores the need to consider the complexity of mutual interactions of pathophysiological processes, which calls for tailoring the management strategies depending on the subgroups which patients belong to, be it obesity, children, or elderly. The chapters also tackle biological diseases with genetic underpinnings. The application of genetics to identify the molecular alterations or mutations will serve well both diagnostics and targeted optimization of treatment; the poignant exemplar being the histological subtypes of lung cancer. The book provides a source of current facts and trends in clinical research and practice. Prevalence of olfactory impairment in granulomatosis with polyangiitis / K. Zycinska [and others] -- Biochemistry of oxidative stress / Michał P. Pruchniak, Magdalena Araźna, Urszula Demkow -- Usage of over-the-counter and herbal products in common cold in Poland: findings from consumer survey / K. Karlowicz-Bodalska [and others] -- RAR[beta] promoter methylation as an epigenetic mechanism of gene silencing in non-small cell lung cancer / A. Dutkowska [and others] -- Cardiovascular risk factors in obese children and adolescents / Małgorzata Rumińska [and others] -- Nutrition and immune system in children with simple obesity / Aneta Czerwonogrodzka-Senczyna [and others] -- The influence of shockwave therapy on orthodontic tooth movement induced in the rat / Hagai Hazan-Molina, Itay Aizenbud, Hana Kaufman, Sorin Teich, Dror Aizenbud -- Thyroid hormone levels and TSH activity in patients with obstructive sleep apnea syndrome / P. Bielicki, T. Przybyłowski, M. Kumor, M. Barnaś, M. Wiercioch, R. Chazan -- Age and gender-related changes in biogenic amine metabolites in cerebrospinal fluid in children / Katarzyna Kuśmierska [and others] -- The influence of primary cytomegalovirus or Epstein-Barr virus infection on the course of idiopathic thrombocytopenic purpura / Katarzyna Smalisz-Skrzypczyk [and others]. Prevalence of Olfactory Impairment in Granulomatosis with polyangiitis, K. Życińska et al -- Biochemistry of Oxidative Stress, M.P. Pruchniak, M. Araźna, U. Demkow -- Usage of Over-the-Counter and Herbal Products in Common Cold in Poland: Findings from Consumer Survey, K. Karlowicz-Bodalska et al -- RARβ Promoter Methylation as an Epigenetic Mechanism of Gene Silencing in Non-Small Cell Lung Cancer, A. Dutkowska et al -- Cardiovascular Risk Factors in Obese Children and Adolescents, M. Rumińska et al -- Nutrition and Immune System in Children with Simple Obesity, A. Czerwonogrodzka-Senczyna et al -- The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat, H. Hazan-Molina, I. Aizenbud, H. Kaufman, S. Teich, D. Aizenbud -- Thyroid Hormone Levels and TSH Activity in Patients with Obstructive Sleep Apnea Syndrome, P. Bielicki et al -- Age and Gender-Related Changes in Biogenic Amine Metabolites in Cerebrospinal Fluid in Children, K. Kuśmierska et al -- The Influence of Primary Cytomegalovirus or Epstein-Barr Virus Infection on the Course of Idiopathic Thrombocytopenic Purpura, K. Smalisz-Skrzypczyk et al -- Index.