Abstract
Sequence analysis of all the exons of EIF4G1 in 96 Asian patients with Parkinson's disease (PD) did not reveal any pathogenic mutations. A novel coding variant (Pro693Ser) in exon 15 (position 2077) was detected in one PD patient but not in 539 control subjects. Analysis of a coding polymorphic variant (rs2178403) in 1330 subjects revealed similar frequency between control subjects (0.638) and PD patients (0.640). EIF4G1 is an uncommon cause of PD in our Asian cohort. © 2013 Elsevier Inc.
Author supplied keywords
Cite
CITATION STYLE
Zhao, Y., Ho, P., Prakash, K. M., Foo, J. N., Liu, J. J., Au, W. L., … Tan, E. K. (2013). Analysis of EIF4G1 in Parkinson’s disease among Asians. Neurobiology of Aging, 34(4), 1311.e5-1311.e6. https://doi.org/10.1016/j.neurobiolaging.2012.09.003
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
