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Antiamebic activity of new acridinic derivatives against Naegleria and Acanthamoeba species in vitro.

by A Osuna, J I Rodriguez-Santiago, L M Ruiz-Perez, F Gamarro, S Castanys, G Giovannangeli, A M Galy, J P Galy, J C Soyfer, J Barbe show all authors
Chemotherapy (1987)

Abstract

In vitro antiamebic activity of selected acridine derivatives has been investigated against Naegleria and Acanthamoeba species. The most active compounds belong to the 9-thioacridanone and the 1,2,3,4-tetrahydro-9-thioacridanone series. In addition, some structure-activity relationships are proposed.

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