Approach to small fiber neuropathy

Abstract

Small fiber neuropathy (SFN) is due to damage of small-caliber somatic and/or autonomic nerve fibers. It often results in neuropathic pain which may dominate the clinical picture. This chapter discusses the small nerve fibers, thermosensory and nociceptive functions, and small fiber neuropathy. It also includes a brief discussion of testing of small and autonomic fiber functions, though more detailed descriptions are highlighted in Chaps. 10, 11, and 13. Neuropathic pain is discussed in Chap. 80.