Abstract
Aptamers developed for applications in cancer therapy can improve the efficacy of drug treatment and enhance molecular imaging. Aptamers for these purposes are generated from SELEX (Systematic Evolution of Ligands by EXponential enrichment), more precisely cell-based SELEX, a process described in detail in this chapter. Experimental applications are also provided for aptamer-based drugs.
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Donovan, M. J., Meng, L., Chen, T., Zhang, Y., Sefah, K., & Tan, W. (2011). Aptamer–Drug Conjugation for Targeted Tumor Cell Therapy. In Methods in Molecular Biology (Vol. 764, pp. 141–152). Humana Press Inc. https://doi.org/10.1007/978-1-61779-188-8_9
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