Aromatic dioxygenases have been found to catalyse single and tandem oxidation reactions of conjugated polyenes. Rational selection and design of dioxygenases, allied to substrate shape, size and substitution pattern, has been used to control regiochemistry and stereochemistry during the oxygenation process. The resulting enantiopure bioproducts have been increasingly utilised as precursors for new and alternative routes in chiral synthesis.
CITATION STYLE
Boyd, D. R., Sharma, N. D., & Allen, C. C. R. (2001, December 1). Aromatic dioxygenases: Molecular biocatalysis and applications. Current Opinion in Biotechnology. https://doi.org/10.1016/S0958-1669(01)00264-6
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