Background: Excision repair cross complementing group 5 (ERCC5 or XPG) plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light. Mutations in this gene cause a rare autosomal recessive syndrome, and its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity phenotype and cancer risk. However, a series of epidemiological studies on the association between the ERCC5 Asp1104His polymorphism (rs17655, G
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Zhu, M. L., Wang, M., Cao, Z. G., He, J., Shi, T. Y., Xia, K. Q., … Wei, Q. Y. (2012). Association between the ERCC5 asp1104his polymorphism and cancer risk: A meta-analysis. PLoS ONE, 7(7). https://doi.org/10.1371/journal.pone.0036293
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